Search Results - "Derubertis, F. R."

Activation of protein kinase C in glomerular cells in diabetes. Mechanisms and potential links to the pathogenesis of diabetic glomerulopathy by Derubertis, F. R., Craven, P. A.

“…Activation of protein kinase C in glomerular cells in diabetes. Mechanisms and potential links to the pathogenesis of diabetic glomerulopathy. F R Derubertis…”
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Antioxidant inhibition of protein kinase C—signaled increases in transforming growth factor-beta in mesangial cells by Studer, R.K., Craven, P.A., Derubertis, F.R.

“…Protein kinase C (PKC)-signaled increases in transforming growth factor β (TGFβ) have been implicated in the stimulation of matrix protein synthesis induced by…”
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Protein kinase C is activated in glomeruli from streptozotocin diabetic rats: possible mediation by glucose by CRAVEN, P. A, DERUBERTIS, F. R

“…Glomerular inositol content and the turnover of polyphosphoinositides was reduced by 58% in 1-2 wk streptozotocin diabetic rats. Addition of inositol to the…”
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Effects of supplementation with vitamin C or E on albuminuria, glomerular TGF-β, and glomerular size in diabetes by CRAVEN, P. A, DERUBERTIS, F. R, KAGAN, V. E, MELHEM, M, STUDER, R. K

“…Oxidant stress and a reduction in antioxidant status, including reduced plasma and tissue ascorbic acid content, occur in diabetic patients and experimental…”
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Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells by Craven, P. A., Studer, R. K., Felder, J., Phillips, S., DeRubertis, F. R.

“…Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells. P A Craven , R K Studer , J Felder , S Phillips and F R…”
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Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats : evidence for protein kinase C-mediated suppression of the cholinergic response by CRAVEN, P. A, STUDER, R. K, DERUBERTIS, F. R

“…Nitric oxide (NO)-dependent cyclic guanosine monophosphate (cGMP) generation was examined in glomeruli isolated from 1-2-wk and 2-mo streptozotocin diabetic…”
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Role for protein kinase C in the mediation of increased fibronectin accumulation by mesangial cells grown in high-glucose medium by Studer, R. K., Craven, P. A., DeRubertis, F. R.

“…Role for protein kinase C in the mediation of increased fibronectin accumulation by mesangial cells grown in high-glucose medium. R K Studer , P A Craven and F…”
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Regulation of the laminin C1 promoter in cultured mesangial cells by PHILLIPS, S. L, DERUBERTIS, F. R, CRAVEN, P. A

“…Regulation of the laminin C1 promoter in cultured mesangial cells. S L Phillips , F R DeRubertis and P A Craven Department of Molecular Genetics and…”
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Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation and reactive oxygen formation by bile acids by Craven, P A, Pfanstiel, J, DeRubertis, F R

“…Deoxycholate (DOC), chenodeoxycholate, 12-O-tetradecanoyl phorbol-13-acetate (TPA), or 1-oleoyl-2-acetyl-glycerol (OAG) activated colonic epithelial protein…”
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Thromboxane in the pathogenesis of glomerular injury in diabetes by Craven, Patricia A., Melhem, Mona F., DeRubertis, Frederick R.

“…Thromboxane in the pathogenesis of glomerular injury in diabetes. The present study examined the role of thromboxane (TX) in the initiation and progression of…”
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Protein kinase C signals thromboxane induced increases in fibronectin synthesis and TGF-β bioactivity in mesangial cells by Studer, Rebecca K., Negrete, Hilmer, Craven, Patricia A., DeRubertis, Frederick R.

“…Protein kinase C signals thromboxane induced increases in fibronectin synthesis and TGF-β bioactivity in mesangial cells. Previous studies have demonstrated…”
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Effects of aspirin on 1,2-dimethylhydrazine-induced colonic carcinogenesis by Craven, P A, DeRubertis, F R

“…The influence of aspirin (ASA) on 1,2-dimethylhydrazine (1,2-DMH)-induced colonic carcinogenesis was examined in weanling Sprague-Dawley rats. The incidence of…”
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Eicosanoids in the pathogenesis of the functional and structural alterations of the kidney in diabetes by DeRubertis, F R, Craven, P A

“…Diabetes mellitus alters the cellular production of eicosanoids in a number of tissues, including the kidney, and these agents have in turn been implicated in…”
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Role of reactive oxygen in bile salt stimulation of colonic epithelial proliferation by Craven, P A, Pfanstiel, J, DeRubertis, F R

“…Our previous studies had suggested a link between bile salt stimulation of colonic epithelial proliferation and the release and oxygenation of arachidonate via…”
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Bile salt stimulation of colonic epithelial proliferation: evidence for involvement of lipoxygenase products by DERUBERTIS, F. R, CRAVEN, P. A, SAITO, R

“…Prostaglandin E2 (PGE2) and several other prostaglandins synthesized by colon suppress the proliferative activity of colonic epithelium. However, bile salts…”
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Alterations in protein kinase C in 1,2-dimethylhydrazine induced colonic carcinogenesis by CRAVEN, P. A, DERUBERTIS, F. R

“…Protein kinase C activity and the profile of protein kinase C isozymes alpha, beta, and gamma were examined in subcellular fractions of 1,2-dimethylhydrazine…”
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Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation by unsaturated fatty acids by Craven, P A, DeRubertis, F R

“…Some, but not all, studies have suggested that high-fat diets promote colon carcinogenesis, possibly by stimulating the proliferative activity of colonic…”
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Impaired nitric oxide release by glomeruli from diabetic rats by Craven, Patricia A., Studer, Rebecca K., DeRubertis, Frederick R.

“…Basal nitric oxide (NO) production and NO responses to carbamylcholine (CCh) and the Ca 2+ ionophore A23187 were measured with a NO electrode in glomeruli…”
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Activation of protein kinase C reduces thromboxane receptors in glomeruli and mesangial cells by Studer, Rebecca K., Craven, Patricia A., DeRubertis, Frederick R.

“…Activation of protein kinase C reduces thromboxane receptors in glomeruli and mesangial cells. The potential role of protein kinase C (PKC) in the modulation…”
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Overexpression of Cu2+/Zn2+ Superoxide Dismutase Protects Against Early Diabetic Glomerular Injury in Transgenic Mice by CRAVEN, Patricia A, MELHEM, Mona F, PHILLIPS, Stephen L, DERUBERTISL, Frederick R

“…Overexpression of Cu 2+ /Zn 2+ Superoxide Dismutase Protects Against Early Diabetic Glomerular Injury in Transgenic Mice Patricia A. Craven 1 , Mona F. Melhem…”
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