Search Results - "Dermol, Janja"

Nonlinear Dispersive Model of Electroporation for Irregular Nucleated Cells by Chiapperino, Michele Alessandro, Bia, Pietro, Caratelli, Diego, Gielis, Johan, Mescia, Luciano, Dermol‐Černe, Janja, Miklavčič, Damijan

“…In this work, the electroporation phenomenon induced by pulsed electric field on different nucleated biological cells is studied. A nonlinear, non‐local,…”
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Cancellation effect is present in high-frequency reversible and irreversible electroporation by Polajžer, Tamara, Dermol–Černe, Janja, Reberšek, Matej, O'Connor, Rodney, Miklavčič, Damijan

“…•Cancellation effect depends on the inter-phase delay and pulse duration.•Cancellation effect is electroporation-buffer dependent.•Cancellation effect can be…”
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Quantification of cell membrane permeability induced by monopolar and high-frequency bipolar bursts of electrical pulses by Sweeney, Daniel C., Reberšek, Matej, Dermol, Janja, Rems, Lea, Miklavčič, Damijan, Davalos, Rafael V.

“…High-frequency bipolar electric pulses have been shown to mitigate undesirable muscle contraction during irreversible electroporation (IRE) therapy. Here, we…”
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Short microsecond pulses achieve homogeneous electroporation of elongated biological cells irrespective of their orientation in electric field by Dermol-Černe, Janja, Batista Napotnik, Tina, Reberšek, Matej, Miklavčič, Damijan

“…In gene electrotransfer and cardiac ablation with irreversible electroporation, treated muscle cells are typically of elongated shape and their orientation may…”
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High-Intensity Pulsed Electromagnetic Field-Mediated Gene Electrotransfection In Vitro by Kranjc, Matej, Dermol-Černe, Janja, Potočnik, Tjaša, Novickij, Vitalij, Miklavčič, Damijan

“…A high-intensity pulsed electromagnetic field (HI-PEMF) is a non-invasive and non-contact delivery method and may, as such, have an advantage over gene…”
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Cell Electrosensitization Exists Only in Certain Electroporation Buffers by Dermol, Janja, Pakhomova, Olga N, Pakhomov, Andrei G, Miklavčič, Damijan

“…Electroporation-induced cell sensitization was described as the occurrence of a delayed hypersensitivity to electric pulses caused by pretreating cells with…”
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The equivalence of different types of electric pulses for electrochemotherapy with cisplatin − an in vitro study by Scuderi, Maria, Dermol-Cerne, Janja, Scancar, Janez, Markovic, Stefan, Rems, Lea, Miklavcic, Damijan

“…Electrochemotherapy (ECT) is a treatment involving the administration of chemotherapeutics drugs followed by the application of 8 square monopolar pulses of…”
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Membrane permeabilization of mammalian cells using bursts of high magnetic field pulses by Novickij, Vitalij, Dermol, Janja, Grainys, Audrius, Kranjc, Matej, Miklavčič, Damijan

“…Cell membrane permeabilization by pulsed electromagnetic fields (PEMF) is a novel contactless method which results in effects similar to conventional…”
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Characterization of Experimentally Observed Complex Interplay between Pulse Duration, Electrical Field Strength, and Cell Orientation on Electroporation Outcome Using a Time-Dependent Nonlinear Numerical Model by Scuderi, Maria, Dermol-Černe, Janja, Batista Napotnik, Tina, Chaigne, Sebastien, Bernus, Olivier, Benoist, David, Sigg, Daniel C, Rems, Lea, Miklavčič, Damijan

“…Electroporation is a biophysical phenomenon involving an increase in cell membrane permeability to molecules after a high-pulsed electric field is applied to…”
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Design, Development, and Testing of a Device for Gene Electrotransfer to Skin Cells In Vivo by Cvetkoska, Aleksandra, Dermol-Černe, Janja, Miklavčič, Damijan, Kranjc Brezar, Simona, Markelc, Boštjan, Serša, Gregor, Reberšek, Matej

“…Gene electrotransfer (GET) is considered one of the most efficient, safe, reproducible, and cost-effective methods of gene therapy, in which a gene is…”
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From Cell to Tissue Properties—Modeling Skin Electroporation With Pore and Local Transport Region Formation by Dermol-Cerne, Janja, Miklavcic, Damijan

“…Current models of tissue electroporation either describe tissue with its bulk properties or include cell level properties, but model only a few cells of simple…”
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Mechanistic view of skin electroporation - models and dosimetry for successful applications: an expert review by Dermol-Černe, Janja, Pirc, Eva, Miklavčič, Damijan

“…: Skin electroporation is a promising treatment for transdermal drug delivery, gene electrotransfer, skin rejuvenation, electrochemotherapy, and wound…”
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Connecting the in vitro and in vivo experiments in electrochemotherapy - a feasibility study modeling cisplatin transport in mouse melanoma using the dual-porosity model by Dermol-Černe, Janja, Vidmar, Janja, Ščančar, Janez, Uršič, Katja, Serša, Gregor, Miklavčič, Damijan

“…In electrochemotherapy two conditions have to be met to be successful – the electric field of sufficient amplitude and sufficient uptake of chemotherapeutics…”
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The use of high-frequency short bipolar pulses in cisplatin electrochemotherapy in vitro by Scuderi, Maria, Rebersek, Matej, Miklavcic, Damijan, Dermol-Cerne, Janja

“…Background In electrochemotherapy (ECT), chemotherapeutics are first administered, followed by short 100 μs monopolar pulses. However, these pulses cause pain…”
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A Multiscale Computational Model of Skeletal Muscle Electroporation Validated Using In Situ Porcine Experiments by Smerc, Rok, Ramirez, David A., Mahnic-Kalamiza, Samo, Dermol-Cerne, Janja, Sigg, Daniel C., Mattison, Lars M., Iaizzo, Paul A., Miklavcic, Damijan

“…Objective: The goal of our study was to determine the importance of electric field orientation in an anisotropic muscle tissue for the extent of irreversible…”
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Me2SO- and serum-free cryopreservation of human umbilical cord mesenchymal stem cells using electroporation-assisted delivery of sugars by Mutsenko, Vitalii, Barlič, Ariana, Pezić, Tamara, Dermol-Černe, Janja, Dovgan, Barbara, Sydykov, Bulat, Wolkers, Willem F., Katkov, Igor I., Glasmacher, Birgit, Miklavčič, Damijan, Gryshkov, Oleksandr

“…Cryopreservation is the universal technology used to enable long-term storage and continuous availability of cell stocks and tissues for regenerative medicine…”
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Plasma membrane depolarization and permeabilization due to electric pulses in cell lines of different excitability by Dermol-Černe, Janja, Miklavčič, Damijan, Reberšek, Matej, Mekuč, Primož, Bardet, Sylvia M., Burke, Ryan, Arnaud-Cormos, Delia, Leveque, Philippe, O'Connor, Rodney

“…In electroporation-based medical treatments, excitable tissues are treated, either intentionally (irreversible electroporation of brain cancer, gene…”
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Mathematical Models Describing Chinese Hamster Ovary Cell Death Due to Electroporation In Vitro by Dermol, Janja, Miklavčič, Damijan

“…Electroporation is a phenomenon used in the treatment of tumors by electrochemotherapy, non-thermal ablation with irreversible electroporation, and gene…”
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Predicting electroporation of cells in an inhomogeneous electric field based on mathematical modeling and experimental CHO-cell permeabilization to propidium iodide determination by Dermol, Janja, Miklavčič, Damijan

“…High voltage electric pulses cause electroporation of the cell membrane. Consequently, flow of the molecules across the membrane increases. In our study we…”
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Models of electroporation and the associated transmembrane molecular transport should be revisited by Scuderi, Maria, Dermol-Černe, Janja, Amaral da Silva, Clarissa, Muralidharan, Aswin, Boukany, Pouyan E., Rems, Lea

“…•Critical assessment of models describing electroporation and molecular transport.•None of the models can be universily applied to the full range of…”
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