Search Results - "Derks, Yvonne H. W."

Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre)clinical studies by Privé, Bastiaan M., Boussihmad, Mohamed A., Timmermans, Bart, van Gemert, Willemijn A., Peters, Steffie M. B., Derks, Yvonne H. W., van Lith, Sanne A. M., Mehra, Niven, Nagarajah, James, Heskamp, Sandra, Westdorp, Harm

“…Introduction Fibroblast activation protein (FAP) is highly overexpressed in stromal tissue of various cancers. While FAP has been recognized as a potential…”
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89Zr-labeled PSMA ligands for pharmacokinetic PET imaging and dosimetry of PSMA-617 and PSMA-I&T: a preclinical evaluation and first in man by Privé, Bastiaan M., Derks, Yvonne H. W., Rosar, Florian, Franssen, Gerben M., Peters, Steffie M. B., Khreish, Fadi, Bartholomä, Mark, Maus, Stephan, Gotthardt, Martin, Laverman, Peter, Konijnenberg, Mark W., Ezziddin, Samer, Nagarajah, James, Heskamp, Sandra

“…Rationale Prolonged in vivo evaluation of PSMA tracers could improve tumor imaging and patient selection for 177 Lu-PSMA-617 and 177 Lu-PSMA-I&T. In this…”
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[89Zr]Zr-PSMA-617 PET/CT in biochemical recurrence of prostate cancer: first clinical experience from a pilot study including biodistribution and dose estimates by Rosar, Florian, Schaefer-Schuler, Andrea, Bartholomä, Mark, Maus, Stephan, Petto, Sven, Burgard, Caroline, Privé, Bastiaan M., Franssen, Gerben M., Derks, Yvonne H. W., Nagarajah, James, Khreish, Fadi, Ezziddin, Samer

“…Purpose Prostate-specific membrane antigen (PSMA)-targeted PET/CT has become increasingly important in the management of prostate cancer, especially in…”
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Theranostic PSMA ligands with optimized backbones for intraoperative multimodal imaging and photodynamic therapy of prostate cancer by Derks, Yvonne H. W., van Lith, Sanne A. M., Amatdjais-Groenen, Helene I. V., Wouters, Lieke W. M., Kip, Annemarie, Franssen, Gerben M., Laverman, Peter, Löwik, Dennis W. P. M., Heskamp, Sandra, Rijpkema, Mark

“…  Introduction The first generation ligands for prostate-specific membrane antigen (PSMA)–targeted radio- and fluorescence-guided surgery followed by adjuvant…”
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Strain-Promoted Azide–Alkyne Cycloaddition-Based PSMA-Targeting Ligands for Multimodal Intraoperative Tumor Detection of Prostate Cancer by Derks, Yvonne H. W, Rijpkema, Mark, Amatdjais-Groenen, Helene I. V, Loeff, Cato C, de Roode, Kim E, Kip, Annemarie, Laverman, Peter, Lütje, Susanne, Heskamp, Sandra, Löwik, Dennis W. P. M

“…Strain-promoted azide–alkyne cycloaddition (SPAAC) is a straightforward and multipurpose conjugation strategy. The use of SPAAC to link different functional…”
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Imaging and photodynamic therapy of prostate cancer using a theranostic PSMA-targeting ligand by Derks, Yvonne H. W., Schilham, Melline G. M., Rijpkema, Mark, Smeets, Esther M. M., Amatdjais-Groenen, Helene I. V., Kip, Annemarie, van Lith, Sanne A. M., van de Kamp, Jill, Sedelaar, J. P. Michiel, Somford, Diederik M., Simons, Michiel, Laverman, Peter, Gotthardt, Martin, Löwik, Dennis W. P. M., Heskamp, Sandra, Lütje, Susanne

“…Purpose Incomplete resection of prostate cancer (PCa) results in increased risk of disease recurrence. Combined fluorescence-guided surgery with tumor-targeted…”
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PSMA-targeting agents for radio- and fluorescence-guided prostate cancer surgery by Derks, Yvonne H W, Löwik, Dennis W P M, Sedelaar, J P Michiel, Gotthardt, Martin, Boerman, Otto C, Rijpkema, Mark, Lütje, Susanne, Heskamp, Sandra

“…Despite recent improvements in imaging and therapy, prostate cancer (PCa) still causes substantial morbidity and mortality. In surgical treatment, incomplete…”
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89Zr-PSMA-617 PET/CT May Reveal Local Recurrence of Prostate Cancer Unidentified by 68Ga-PSMA-11 PET/CT by Rosar, Florian, Bartholomä, Mark, Maus, Stephan, Privé, Bastiaan M., Khreish, Fadi, Franssen, Gerben M., Derks, Yvonne H.W., Nagarajah, James, Ezziddin, Samer

“…For localization of biochemical recurrence of prostate cancer, 68Ga-PSMA-11 PET/CT imaging was performed in a 66-year-old man with no suspicious findings at 1…”
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Photosensitizer-based multimodal PSMA-targeting ligands for intraoperative detection of prostate cancer by Derks, Yvonne H W, Rijpkema, Mark, Amatdjais-Groenen, Helene I V, Kip, Annemarie, Franssen, Gerben M, Sedelaar, J P Michiel, Somford, Diederik M, Simons, Michiel, Laverman, Peter, Gotthardt, Martin, Löwik, Dennis W P M, Lütje, Susanne, Heskamp, Sandra

“…Incomplete resection of prostate cancer (PCa) occurs in 15%-50% of PCa patients. Disease recurrence negatively impacts oncological outcome. The use of radio-,…”
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The transcriptional repressor SNAI2 impairs neuroblastoma differentiation and inhibits response to retinoic acid therapy by Vrenken, Kirsten S., Vervoort, Britt M.T., van Ingen Schenau, Dorette S., Derks, Yvonne H.W., van Emst, Liesbeth, Grytsenko, Pavlo G., Middelbeek, Jeroen A.J., van Leeuwen, Frank N.

“…Neuroblastoma is the most common extracranial solid tumor in children and originates from poorly differentiated neural crest progenitors. High-risk…”
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Targeting Kidney Fibrosis with Polymeric Nanocarriers by Kulkarni, Vedangi, Caspers, Tim, Moeckel, Diana, Koletnik, Susanne, Rama, Elena, Sotiropoulou, Paraskevi, Dietrich, Daniel R., Pola, Robert, Kotrchová, Lenka, Etrych, Tomáš, Derks, Yvonne H. W., Boor, Peter, Kiessling, Fabian, Mottaghy, Felix M., Klinkhammer, Barbara M., Lammers, Twan

“…Chronic kidney disease (CKD) presents a significant health challenge, affecting nearly 10% of the global population. The management of CKD is hampered by the…”
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89Zr-PSMA-617 PET/CT May Reveal Local Recurrence of Prostate Cancer Unidentified by 68Ga-PSMA-11 PET/CT by Rosar, Florian, Bartholomä, Mark, Maus, Stephan, Privé, Bastiaan M., Khreish, Fadi, Franssen, Gerben M., Derks, Yvonne H.W., Nagarajah, James, Ezziddin, Samer

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89 Zr-labeled PSMA ligands for pharmacokinetic PET imaging and dosimetry of PSMA-617 and PSMA-I&T: a preclinical evaluation and first in man by Privé, Bastiaan M, Derks, Yvonne H W, Rosar, Florian, Franssen, Gerben M, Peters, Steffie M B, Khreish, Fadi, Bartholomä, Mark, Maus, Stephan, Gotthardt, Martin, Laverman, Peter, Konijnenberg, Mark W, Ezziddin, Samer, Nagarajah, James, Heskamp, Sandra

“…Prolonged in vivo evaluation of PSMA tracers could improve tumor imaging and patient selection for Lu-PSMA-617 and Lu-PSMA-I&T. In this study, we present the…”
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