Search Results - "Derks, Martijn F. L."

Coping with living in the soil: the genome of the parthenogenetic springtail Folsomia candida by Faddeeva-Vakhrusheva, Anna, Kraaijeveld, Ken, Derks, Martijn F L, Anvar, Seyed Yahya, Agamennone, Valeria, Suring, Wouter, Kampfraath, Andries A, Ellers, Jacintha, Le Ngoc, Giang, van Gestel, Cornelis A M, Mariën, Janine, Smit, Sandra, van Straalen, Nico M, Roelofs, Dick

“…Folsomia candida is a model in soil biology, belonging to the family of Isotomidae, subclass Collembola. It reproduces parthenogenetically in the presence of…”
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Large scale sequence-based screen for recessive variants allows for identification and monitoring of rare deleterious variants in pigs by Boshove, Anne, Derks, Martijn F L, Sevillano, Claudia A, Lopes, Marcos S, van Son, Maren, Knol, Egbert F, Dibbits, Bert, Harlizius, Barbara

“…Most deleterious variants are recessive and segregate at relatively low frequency. Therefore, high sample sizes are required to identify these variants. In…”
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Loss of function mutations in essential genes cause embryonic lethality in pigs by Derks, Martijn F L, Gjuvsland, Arne B, Bosse, Mirte, Lopes, Marcos S, van Son, Maren, Harlizius, Barbara, Tan, Beatrice F, Hamland, Hanne, Grindflek, Eli, Groenen, Martien A M, Megens, Hendrik-Jan

“…Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals, reducing fertility. Especially in small size domestic and wild…”
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Balancing selection on a recessive lethal deletion with pleiotropic effects on two neighboring genes in the porcine genome by Derks, Martijn F L, Lopes, Marcos S, Bosse, Mirte, Madsen, Ole, Dibbits, Bert, Harlizius, Barbara, Groenen, Martien A M, Megens, Hendrik-Jan

“…Livestock populations can be used to study recessive defects caused by deleterious alleles. The frequency of deleterious alleles including recessive lethal…”
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A systematic survey to identify lethal recessive variation in highly managed pig populations by Derks, Martijn F L, Megens, Hendrik-Jan, Bosse, Mirte, Lopes, Marcos S, Harlizius, Barbara, Groenen, Martien A M

“…Lethal recessive variation can cause prenatal death of homozygous offspring. Although usually present at low-frequency in populations, the impact on individual…”
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Using short read sequencing to characterise balanced reciprocal translocations in pigs by Bouwman, Aniek C, Derks, Martijn F L, Broekhuijse, Marleen L W J, Harlizius, Barbara, Veerkamp, Roel F

“…A balanced constitutional reciprocal translocation (RT) is a mutual exchange of terminal segments of two non-homologous chromosomes without any loss or gain of…”
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A survey of functional genomic variation in domesticated chickens by Derks, Martijn F L, Megens, Hendrik-Jan, Bosse, Mirte, Visscher, Jeroen, Peeters, Katrijn, Bink, Marco C A M, Vereijken, Addie, Gross, Christian, de Ridder, Dick, Reinders, Marcel J T, Groenen, Martien A M

“…Deleterious genetic variation can increase in frequency as a result of mutations, genetic drift, and genetic hitchhiking. Although individual effects are often…”
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Preimplantation Genetic Testing for Aneuploidy (PGT-A) Reveals High Levels of Chromosomal Errors in In Vivo-Derived Pig Embryos, with an Increased Incidence When Produced In Vitro by Jochems, Reina, Canedo-Ribeiro, Carla, Silvestri, Giuseppe, Derks, Martijn F L, Hamland, Hanne, Zak, Louisa J, Knol, Egbert F, Handyside, Alan H, Grindflek, Eli, Griffin, Darren K

“…Preimplantation genetic testing for aneuploidy (PGT-A) is widespread, but controversial, in humans and improves pregnancy and live birth rates in cattle. In…”
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Early and late feathering in turkey and chicken: same gene but different mutations by Derks, Martijn F L, Herrero-Medrano, Juan M, Crooijmans, Richard P M A, Vereijken, Addie, Long, Julie A, Megens, Hendrik-Jan, Groenen, Martien A M

“…Sex-linked slow (SF) and fast (FF) feathering rates at hatch have been widely used in poultry breeding for autosexing at hatch. In chicken, the sex-linked K…”
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Review: Balancing Selection for Deleterious Alleles in Livestock by Derks, Martijn F L, Steensma, Marije

“…Harmful alleles can be under balancing selection due to an interplay of artificial selection for the variant in heterozygotes and purifying selection against…”
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Gene and transposable element methylation in great tit (Parus major) brain and blood by Derks, Martijn F L, Schachtschneider, Kyle M, Madsen, Ole, Schijlen, Elio, Verhoeven, Koen J F, van Oers, Kees

“…Studies on vertebrate DNA methylomes have revealed a regulatory role of tissue specific DNA methylation in relation to gene expression. However, it is not well…”
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Editorial: Early Domestication and Artificial Selection of Animals by Xiang, Hai, Derks, Martijn F L, Yi, Guoqiang, Zhao, Xingbo

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Meta-Analysis of SNPs Determining Litter Traits in Pigs by Sell-Kubiak, Ewa, Dobrzanski, Jan, Derks, Martijn F L, Lopes, Marcos S, Szwaczkowski, Tomasz

“…Nearly 2000 SNPs associated with pig litter size traits have been reported based on genome-wide association studies (GWASs). The aims of this study were to…”
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A footprint of desiccation tolerance in the genome of Xerophyta viscosa by Costa, Maria-Cecília D., Artur, Mariana A. S., Maia, Julio, Jonkheer, Eef, Derks, Martijn F. L., Nijveen, Harm, Williams, Brett, Mundree, Sagadevan G., Jiménez-Gómez, José M., Hesselink, Thamara, Schijlen, Elio G. W. M., Ligterink, Wilco, Oliver, Melvin J., Farrant, Jill M., Hilhorst, Henk W. M.

“…Desiccation tolerance is common in seeds and various other organisms, but only a few angiosperm species possess vegetative desiccation tolerance. These…”
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The type of bottleneck matters: Insights into the deleterious variation landscape of small managed populations by Bortoluzzi, Chiara, Bosse, Mirte, Derks, Martijn F. L., Crooijmans, Richard P. M. A., Groenen, Martien A. M., Megens, Hendrik‐Jan

“…Predictions about the consequences of a small population size on genetic and deleterious variation are fundamental to population genetics. As small populations…”
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Identification of the genetic basis of sow pelvic organ prolapse by Bhatia, Vishesh, Stevens, Tomas, Derks, Martijn F L, Dunkelberger, Jenelle, Knol, Egbert F, Ross, Jason W, Dekkers, Jack C M

“…Pelvic organ prolapse (POP) is one contributor to recent increases in sow mortality that have been observed in some populations and environments, leading to…”
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Corrigendum: A novel loss-of-function variant in transmembrane protein 263 (TMEM263) of autosomal dwarfism in chicken by Wu, Zhou, Derks, Martijn F L, Dibbits, Bert, Megens, Hendrik-Jan, Groenen, Martien A M, Crooijmans, Richard P M A

“…[This corrects the article DOI: 10.3389/fgene.2018.00193.]…”
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A QTL for Number of Teats Shows Breed Specific Effects on Number of Vertebrae in Pigs: Bridging the Gap Between Molecular and Quantitative Genetics by van Son, Maren, Lopes, Marcos S, Martell, Henry J, Derks, Martijn F L, Gangsei, Lars Erik, Kongsro, Jorgen, Wass, Mark N, Grindflek, Eli H, Harlizius, Barbara

“…Modern breeding schemes for livestock species accumulate a large amount of genotype and phenotype data which can be used for genome-wide association studies…”
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Fine Mapping of a Major Backfat QTL Reveals a Causal Regulatory Variant Affecting the CCND2 Gene by Oliveira, Haniel C, Derks, Martijn F L, Lopes, Marcos S, Madsen, Ole, Harlizius, Barbara, van Son, Maren, Grindflek, Eli H, Gòdia, Marta, Gjuvsland, Arne B, Otto, Pamela Itajara, Groenen, Martien A M, Guimaraes, Simone E F

“…Backfat is an important trait in pork production, and it has been included in the breeding objectives of genetic companies for decades. Although adipose tissue…”
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Heterogeneity of a dwarf phenotype in Dutch traditional chicken breeds revealed by genomic analyses by Wu, Zhou, Bortoluzzi, Chiara, Derks, Martijn F. L., Liu, Langqing, Bosse, Mirte, Hiemstra, Sipke Joost, Groenen, Martien A. M., Crooijmans, Richard P. M. A.

“…The growth of animals is a complex trait, in chicken resulting in a diverse variety of forms, caused by a heterogeneous genetic basis. Bantam chicken, known as…”
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