Search Results - "Deriu, A."

Toward a holographic brain paradigm: a lipid-centric model of brain functioning by Cavaglià, Marco, Deriu, Marco A, Tuszynski, Jack A

“…Due to the stimulation of neuronal membrane dipoles by action potentials, under suitable conditions coherent dipole oscillations can be formed. We argue that…”
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Reconstitution of microtubule into GTP-responsive nanocapsules by Uchida, Noriyuki, Kohata, Ai, Okuro, Kou, Cardellini, Annalisa, Lionello, Chiara, Zizzi, Eric A., Deriu, Marco A., Pavan, Giovanni M., Tomishige, Michio, Hikima, Takaaki, Aida, Takuzo

“…Nanocapsules that collapse in response to guanosine triphosphate (GTP) have the potential as drug carriers for efficiently curing diseases caused by cancer and…”
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VirtuousPocketome: a computational tool for screening protein–ligand complexes to identify similar binding sites by Pallante, Lorenzo, Cannariato, Marco, Androutsos, Lampros, Zizzi, Eric A., Bompotas, Agorakis, Hada, Xhesika, Grasso, Gianvito, Kalogeras, Athanasios, Mavroudi, Seferina, Di Benedetto, Giacomo, Theofilatos, Konstantinos, Deriu, Marco A.

“…Protein residues within binding pockets play a critical role in determining the range of ligands that can interact with a protein, influencing its structure…”
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Deformation pattern in vibrating microtubule: Structural mechanics study based on an atomistic approach by Havelka, Daniel, Deriu, Marco A., Cifra, Michal, Kučera, Ondřej

“…The mechanical properties of microtubules are of great importance for understanding their biological function and for applications in artificial devices…”
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Toward a general and interpretable umami taste predictor using a multi-objective machine learning approach by Pallante, Lorenzo, Korfiati, Aigli, Androutsos, Lampros, Stojceski, Filip, Bompotas, Agorakis, Giannikos, Ioannis, Raftopoulos, Christos, Malavolta, Marta, Grasso, Gianvito, Mavroudi, Seferina, Kalogeras, Athanasios, Martos, Vanessa, Amoroso, Daria, Piga, Dario, Theofilatos, Konstantinos, Deriu, Marco A.

“…The umami taste is one of the five basic taste modalities normally linked to the protein content in food. The implementation of fast and cost-effective tools…”
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Prediction of Protein-Protein Interactions Between Alsin DH/PH and Rac1 and Resulting Protein Dynamics by Cannariato, Marco, Miceli, Marcello, Cavaglià, Marco, Deriu, Marco A

“…Alsin is a protein of 1,657 amino acids known for its crucial role in vesicular trafficking in neurons thanks to its ability to interact with two guanosine…”
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Conformational Dynamics and Stability of U-Shaped and S-Shaped Amyloid β Assemblies by Grasso, Gianvito, Rebella, Martina, Muscat, Stefano, Morbiducci, Umberto, Tuszynski, Jack, Danani, Andrea, Deriu, Marco A

“…Alzheimer's disease is the most fatal neurodegenerative disorder characterized by the aggregation and deposition of Amyloid β (Aβ) oligomers in the brain of…”
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A Versatile Bioreactor for Dynamic Suspension Cell Culture. Application to the Culture of Cancer Cell Spheroids by Massai, Diana, Isu, Giuseppe, Madeddu, Denise, Cerino, Giulia, Falco, Angela, Frati, Caterina, Gallo, Diego, Deriu, Marco A, Falvo D'Urso Labate, Giuseppe, Quaini, Federico, Audenino, Alberto, Morbiducci, Umberto

“…A versatile bioreactor suitable for dynamic suspension cell culture under tunable shear stress conditions has been developed and preliminarily tested culturing…”
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Correction: Electro-Acoustic Behavior of the Mitotic Spindle: A Semi-Classical Coarse-Grained Model by Havelka, Daniel, Kučera, Ondřej, Deriu, Marco A, Cifra, Michal

“…[This corrects the article DOI: 10.1371/journal.pone.0086501.]…”
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Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore by Trofimenko, Evgeniya, Grasso, Gianvito, Heulot, Mathieu, Chevalier, Nadja, Deriu, Marco A, Dubuis, Gilles, Arribat, Yoan, Serulla, Marc, Michel, Sebastien, Vantomme, Gil, Ory, Florine, Dam, Linh Chi, Puyal, Julien, Amati, Francesca, Lüthi, Anita, Danani, Andrea, Widmann, Christian

“…Cell-penetrating peptides (CPPs) allow intracellular delivery of bioactive cargo molecules. The mechanisms allowing CPPs to enter cells are ill-defined. Using…”
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Electro-acoustic behavior of the mitotic spindle: a semi-classical coarse-grained model by Havelka, Daniel, Kučera, Ondřej, Deriu, Marco A, Cifra, Michal

“…The regulation of chromosome separation during mitosis is not fully understood yet. Microtubules forming mitotic spindles are targets of treatment strategies…”
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Outflow conditions for image-based hemodynamic models of the carotid bifurcation: implications for indicators of abnormal flow by Morbiducci, Umberto, Gallo, Diego, Massai, Diana, Consolo, Filippo, Ponzini, Raffaele, Antiga, Luca, Bignardi, Cristina, Deriu, Marco A, Redaelli, Alberto

“…Computational fluid dynamics (CFD) models have become very effective tools for predicting the flow field within the carotid bifurcation, and for understanding…”
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A Model-Agnostic Algorithm for Bayes Error Determination in Binary Classification by Michelucci, Umberto, Sperti, Michela, Piga, Dario, Venturini, Francesca, Deriu, Marco A.

“…This paper presents the intrinsic limit determination algorithm (ILD Algorithm), a novel technique to determine the best possible performance, measured in…”
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Anisotropic Elastic Network Modeling of Entire Microtubules by Deriu, Marco A., Soncini, Monica, Orsi, Mario, Patel, Mishal, Essex, Jonathan W., Montevecchi, Franco M., Redaelli, Alberto

“…Microtubules are supramolecular structures that make up the cytoskeleton and strongly affect the mechanical properties of the cell. Within the cytoskeleton…”
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Formation of self-organized nanoparticles by lecithin/chitosan ionic interaction by Sonvico, F., Cagnani, A., Rossi, A., Motta, S., Di Bari, M.T., Cavatorta, F., Alonso, M.J., Deriu, A., Colombo, P.

“…In this work the production of auto-assembled nanoparticles obtained by the mixing of chitosan and lecithin is presented. The size and surface charge of the…”
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Josephin Domain Structural Conformations Explored by Metadynamics in Essential Coordinates by Deriu, Marco A, Grasso, Gianvito, Tuszynski, Jack A, Gallo, Diego, Morbiducci, Umberto, Danani, Andrea

“…The Josephin Domain (JD), i.e. the N-terminal domain of Ataxin 3 (At3) protein, is an interesting example of competition between physiological function and…”
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Using the Gibbs Function as a Measure of Human Brain Development Trends from Fetal Stage to Advanced Age by Rietman, Edward A, Taylor, Sophie, Siegelmann, Hava T, Deriu, Marco A, Cavaglia, Marco, Tuszynski, Jack A

“…We propose to use a Gibbs free energy function as a measure of the human brain development. We adopt this approach to the development of the human brain over…”
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Structure Based Modeling of Small Molecules Binding to the TLR7 by Atomistic Level Simulations by Gentile, Francesco, Deriu, Marco A, Licandro, Ginevra, Prunotto, Alessio, Danani, Andrea, Tuszynski, Jack A

“…Toll-Like Receptors (TLR) are a large family of proteins involved in the immune system response. Both the activation and the inhibition of these receptors can…”
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The synergistic effect of chlorotoxin-mApoE in boosting drug-loaded liposomes across the BBB by Formicola, Beatrice, Dal Magro, Roberta, Montefusco-Pereira, Carlos V, Lehr, Claus-Michael, Koch, Marcus, Russo, Laura, Grasso, Gianvito, Deriu, Marco A, Danani, Andrea, Bourdoulous, Sandrine, Re, Francesca

“…We designed liposomes dually functionalized with ApoE-derived peptide (mApoE) and chlorotoxin (ClTx) to improve their blood-brain barrier (BBB) crossing. Our…”
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Informed classification of sweeteners/bitterants compounds via explainable machine learning by Maroni, Gabriele, Pallante, Lorenzo, Di Benedetto, Giacomo, Deriu, Marco A., Piga, Dario, Grasso, Gianvito

“…Perception of taste is an emergent phenomenon arising from complex molecular interactions between chemical compounds and specific taste receptors. Among all…”
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