Search Results - "Derebe, Mehabaw Getahun"
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Crystal structure of a potassium ion transporter, TrkH
Published in Nature (London) (17-03-2011)“…The TrkH/TrkG/KtrB proteins mediate K + uptake in bacteria and probably evolved from simple K + channels by multiple gene duplications or fusions. Here we…”
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The effects of intramolecular and intermolecular electrostatic repulsions on the stability and aggregation of NISTmAb revealed by HDX‐MS, DSC, and nanoDSF
Published in Protein science (01-08-2021)“…The stability and aggregation of NIST monoclonal antibody (NISTmAb) were investigated by hydrogen/deuterium exchange mass spectrometry (HDX‐MS), differential…”
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3
Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel
Published in eLife (13-12-2012)“…The gating ring-forming RCK domain regulates channel gating in response to various cellular chemical stimuli in eukaryotic Slo channel families and the…”
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In Pursuit of Stability Enhancement of a Prostate Cancer Targeting Antibody Derived from a Transgenic Animal Platform
Published in Scientific reports (16-06-2020)“…Accelerated timelines necessitate the discovery of fully human antibodies as biotherapeutics using transgenic animals with a notion that such mAbs bypass…”
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5
Synthesis and characterization of some metal complexes of a Schiff base derived from ninhydrin and α,L-alanine
Published in Bulletin of the Chemical Society of Ethiopia (01-06-2002)“…Complexes of Mn(II), Fe(III), Co(II), Ni(II) and Zn(II) with an intermediate Schiff base derived from ninhydrin and α,L-alanine…”
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6
Electrostatically Mediated Attractive Self-Interactions and Reversible Self-Association of Fc-Fusion Proteins
Published in Molecular pharmaceutics (04-03-2024)“…Attractive self-interactions and reversible self-association are implicated in many problematic solution behaviors for therapeutic proteins, such as…”
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Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels
Published in The Journal of general physiology (01-09-2015)“…Calcium permeability and the concomitant calcium block of monovalent ion current ("Ca(2+) block") are properties of cyclic nucleotide-gated (CNG) channel…”
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8
Structural implications of weak Ca^sup 2+^ block in Drosophila cyclic nucleotide-gated channels
Published in The Journal of general physiology (01-09-2015)“…Calcium permeability and the concomitant calcium block of monovalent ion current ("Ca2+ block") are properties of cyclic nucleotide-gated (CNG) channel…”
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9
Structural implications of weak Ca super( 2+) block in Drosophila cyclic nucleotide-gated channels
Published in The Journal of general physiology (01-09-2015)“…Calcium permeability and the concomitant calcium block of monovalent ion current ("Ca2+ block") are properties of cyclic nucleotide-gated (CNG) channel…”
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10
Crystal structure of a potassium ion transporter, TrkH
Published in Nature (London) (15-10-2015)Get full text
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