Search Results - "Derebe, Mehabaw Getahun"

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    The effects of intramolecular and intermolecular electrostatic repulsions on the stability and aggregation of NISTmAb revealed by HDX‐MS, DSC, and nanoDSF by Hamuro, Yoshitomo, Derebe, Mehabaw Getahun, Venkataramani, Sathya, Nemeth, Jennifer F.

    Published in Protein science (01-08-2021)
    “…The stability and aggregation of NIST monoclonal antibody (NISTmAb) were investigated by hydrogen/deuterium exchange mass spectrometry (HDX‐MS), differential…”
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    Journal Article
  3. 3

    Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel by Kong, Chunguang, Zeng, Weizhong, Ye, Sheng, Chen, Liping, Sauer, David Bryant, Lam, Yeeling, Derebe, Mehabaw Getahun, Jiang, Youxing

    Published in eLife (13-12-2012)
    “…The gating ring-forming RCK domain regulates channel gating in response to various cellular chemical stimuli in eukaryotic Slo channel families and the…”
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    Journal Article
  4. 4

    In Pursuit of Stability Enhancement of a Prostate Cancer Targeting Antibody Derived from a Transgenic Animal Platform by Venkataramani, Sathya, Ernst, Robin, Derebe, Mehabaw Getahun, Wright, Robert, Kopenhaver, Jessica, Jacobs, Steven A., Singh, Sanjaya, Ganesan, Rajkumar

    Published in Scientific reports (16-06-2020)
    “…Accelerated timelines necessitate the discovery of fully human antibodies as biotherapeutics using transgenic animals with a notion that such mAbs bypass…”
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    Journal Article
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    Synthesis and characterization of some metal complexes of a Schiff base derived from ninhydrin and α,L-alanine by Mehabaw Getahun Derebe, V.J.T. Raju, Negussie Retta

    “…Complexes of Mn(II), Fe(III), Co(II), Ni(II) and Zn(II) with an intermediate Schiff base derived from ninhydrin and α,L-alanine…”
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    Electrostatically Mediated Attractive Self-Interactions and Reversible Self-Association of Fc-Fusion Proteins by Forder, James K., Palakollu, Veerabhadraiah, Adhikari, Sudeep, Blanco, Marco A., Derebe, Mehabaw Getahun, Ferguson, Heidi M., Luthra, Suman A., Munsell, Erik V., Roberts, Christopher J.

    Published in Molecular pharmaceutics (04-03-2024)
    “…Attractive self-interactions and reversible self-association are implicated in many problematic solution behaviors for therapeutic proteins, such as…”
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    Journal Article
  7. 7

    Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels by Lam, Yee Ling, Zeng, Weizhong, Derebe, Mehabaw Getahun, Jiang, Youxing

    Published in The Journal of general physiology (01-09-2015)
    “…Calcium permeability and the concomitant calcium block of monovalent ion current ("Ca(2+) block") are properties of cyclic nucleotide-gated (CNG) channel…”
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    Journal Article
  8. 8

    Structural implications of weak Ca^sup 2+^ block in Drosophila cyclic nucleotide-gated channels by Lam, Yee Ling, Zeng, Weizhong, Derebe, Mehabaw Getahun, Jiang, Youxing

    Published in The Journal of general physiology (01-09-2015)
    “…Calcium permeability and the concomitant calcium block of monovalent ion current ("Ca2+ block") are properties of cyclic nucleotide-gated (CNG) channel…”
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    Journal Article
  9. 9

    Structural implications of weak Ca super( 2+) block in Drosophila cyclic nucleotide-gated channels by Lam, Yee Ling, Zeng, Weizhong, Derebe, Mehabaw Getahun, Jiang, Youxing

    Published in The Journal of general physiology (01-09-2015)
    “…Calcium permeability and the concomitant calcium block of monovalent ion current ("Ca2+ block") are properties of cyclic nucleotide-gated (CNG) channel…”
    Get full text
    Journal Article
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