Search Results - "Derebe, Mehabaw G."

Antibacterial membrane attack by a pore-forming intestinal C-type lectin by Mukherjee, Sohini, Zheng, Hui, Derebe, Mehabaw G., Callenberg, Keith M., Partch, Carrie L., Rollins, Darcy, Propheter, Daniel C., Rizo, Josep, Grabe, Michael, Jiang, Qiu-Xing, Hooper, Lora V.

“…Secreted C-type lectins protect the intestinal epithelium from Gram-positive bacteria; this study shows that for the C-type lectin RegIIIα, bacterial killing…”
Get full text

Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites by Derebe, Mehabaw G., Sauer, David B., Zeng, Weizhong, Alam, Amer, Shi, Ning, Jiang, Youxing, Miller, Christopher

“…Selective ion conduction across ion channel pores is central to cellular physiology. To understand the underlying principles of ion selectivity in tetrameric…”
Get full text

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection by Derebe, Mehabaw G, Zlatkov, Clare M, Gattu, Sureka, Ruhn, Kelly A, Vaishnava, Shipra, Diehl, Gretchen E, MacMillan, John B, Williams, Noelle S, Hooper, Lora V

“…Retinol plays a vital role in the immune response to infection, yet proteins that mediate retinol transport during infection have not been identified. Serum…”
Get full text

Structural studies of ion permeation and Ca²⁺ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore by Derebe, Mehabaw G, Zeng, Weizhong, Li, Yang, Alam, Amer, Jiang, Youxing

“…Cyclic nucleotide-gated (CNG) channels play an essential role in the visual and olfactory sensory systems and are ubiquitous in eukaryotes. Details of their…”
Get full text

FcγRII-binding Centyrins mediate agonism and antibody-dependent cellular phagocytosis when fused to an anti-OX40 antibody by Zhang, Di, Whitaker, Brian, Derebe, Mehabaw G, Chiu, Mark L

“…Immunostimulatory antibodies against the tumor necrosis factor receptors (TNFR) are emerging as promising cancer immunotherapies. The agonism activity of such…”
Get full text

Human IgG subclass cross-species reactivity to mouse and cynomolgus monkey Fcγ receptors by Derebe, Mehabaw G., Nanjunda, Rupesh K., Gilliland, Gary L., Lacy, Eilyn R., Chiu, Mark L.

“…•Affinities of human, murine and cyno monkey FcγRs against human IgGs is presented.•Cyno FcγRs had higher affinities to human IgGs compared to corresponding…”
Get full text

Rapid Purification of Human Bispecific Antibodies via Selective Modulation of Protein A Binding by Zwolak, Adam, Leettola, Catherine N., Tam, Susan H., Goulet, Dennis R., Derebe, Mehabaw G., Pardinas, Jose R., Zheng, Songmao, Decker, Rose, Emmell, Eva, Chiu, Mark L.

“…Methods to rapidly generate high quality bispecific antibodies (BsAb) having normal half-lives are critical for therapeutic programs. Here, we identify 3…”
Get full text

Semisynthesis of NaK, a Na+ and K+ Conducting Ion Channel by Linn, Kellie M, Derebe, Mehabaw G, Jiang, Youxing, Valiyaveetil, Francis I

“…In this contribution, we describe the semisynthesis of NaK, a bacterial nonselective cation channel. In the semisynthesis, the NaK polypeptide is assembled…”
Get full text

Single Crystal X-ray Diffraction Study of a Pure Natrolite Sample by Capitelli, Francesco, Derebe, Mehabaw G.

“…The crystal structure of a pure natrolite sample, Na2(Al2Si3O10)·2H2O, coming from Asheken, Ethiopia, has been analysed by single crystal X-ray diffraction. It…”
Get full text

Structural studies of ion permeation and Ca[superscript 2+] blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore by Derebe, Mehabaw G., Zeng, Weizhong, Li, Yang, Alam, Amer, Jiang, Youxing

Get full text

Structural studies of ion permeation and Ca 2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore by Derebe, Mehabaw G., Zeng, Weizhong, Li, Yang, Alam, Amer, Jiang, Youxing

“…Cyclic nucleotide-gated (CNG) channels play an essential role in the visual and olfactory sensory systems and are ubiquitous in eukaryotes. Details of their…”
Get full text

Structural studies of ion permeation and Ca^sup 2+^ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore by Derebe, Mehabaw G, Zeng, Weizhong, Li, Yang, Alam, Amer, Jiang, Youxing

“…Cyclic nucleotide-gated (CNG) channels play an essential role in the visual and olfactory sensory systems and are ubiquitous in eukaryotes. Details of their…”
Get full text