Search Results - "Derdak, Z"

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    Mitochondrial recoupling: a novel therapeutic strategy for cancer? by Baffy, G, Derdak, Z, Robson, S C

    Published in British journal of cancer (09-08-2011)
    “…Recent findings link metabolic transformation of cancer cells to aberrant functions of mitochondrial uncoupling proteins (UCPs). By inducing proton leak, UCPs…”
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    Journal Article
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    Uncoupling protein‐2 deficiency promotes oxidant stress and delays liver regeneration in mice by Horimoto, Masayoshi, Fülöp, Péter, Derdák, Zoltán, Wands, Jack R., Baffy, György

    Published in Hepatology (Baltimore, Md.) (01-02-2004)
    “…The control of liver regeneration remains elusive. Because reactive oxygen species (ROS) are able to mediate cell growth arrest and activate proteins that…”
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    Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-κB activation and oxidative stress by Derdák, Zoltán, Fülöp, Péter, Sabo, Edmond, Tavares, Rose, Berthiaume, Eric P., Resnick, Murray B., Paragh, György, Wands, Jack R., Baffy, György

    Published in Carcinogenesis (New York) (01-05-2006)
    “…Oxidative stress has a complex effect on cancer development. To further study this process, we induced colon tumors with azoxymethane (AOM) in mice deficient…”
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    Journal Article
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    Detection of uncoupling protein-2 (UCP2) as a mitochondrial modulator of apoptosis by Derdak, Zoltan, Garcia, Tamako A, Baffy, Gyorgy

    “…There is an increasing evidence that uncoupling protein-2 (UCP2), a recently identified molecular sensor and suppressor of mitochondrial reactive oxygen…”
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