Search Results - "Derakhshani, Afshin"

Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death by Asadzadeh, Zahra, Safarzadeh, Elham, Safaei, Sahar, Baradaran, Ali, Mohammadi, Ali, Hajiasgharzadeh, Khalil, Derakhshani, Afshin, Argentiero, Antonella, Silvestris, Nicola, Baradaran, Behzad

“…Cell death resistance is a key feature of tumor cells. One of the main anticancer therapies is increasing the susceptibility of cells to death. Cancer cells…”
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Combination of Ipilimumab and Nivolumab in Cancers: From Clinical Practice to Ongoing Clinical Trials by Kooshkaki, Omid, Derakhshani, Afshin, Hosseinkhani, Negar, Torabi, Mitra, Safaei, Sahar, Brunetti, Oronzo, Racanelli, Vito, Silvestris, Nicola, Baradaran, Behzad

“…Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) are inhibitory checkpoints that are commonly seen on activated…”
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Overcoming trastuzumab resistance in HER2‐positive breast cancer using combination therapy by Derakhshani, Afshin, Rezaei, Zohreh, Safarpour, Hossein, Sabri, Morteza, Mir, Atefeh, Sanati, Mohammad Amin, Vahidian, Fatemeh, Gholamiyan Moghadam, Ali, Aghadoukht, Ali, Hajiasgharzadeh, Khalil, Baradaran, Behzad

“…Human epidermal growth factor receptor 2 (HER2)‐positive breast cancer (BC) comprises around 20–30% of all BC subtypes and is correlated with poor prognosis…”
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Neutrophils, Crucial, or Harmful Immune Cells Involved in Coronavirus Infection: A Bioinformatics Study by Hemmat, Nima, Derakhshani, Afshin, Bannazadeh Baghi, Hossein, Silvestris, Nicola, Baradaran, Behzad, De Summa, Simona

“…The latest member of the Coronaviridae family, called SARS-CoV-2, causes the Coronavirus Disease 2019 (COVID-19). The disease has caused a pandemic and is…”
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The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV by Hemmat, Nima, Asadzadeh, Zahra, Ahangar, Noora Karim, Alemohammad, Hajar, Najafzadeh, Basira, Derakhshani, Afshin, Baghbanzadeh, Amir, Baghi, Hossein Bannazadeh, Javadrashid, Darya, Najafi, Souzan, Ar Gouilh, Meriadeg, Baradaran, Behzad

“…The number of descriptions of emerging viruses has grown at an unprecedented rate since the beginning of the 21 st century. Severe acute respiratory syndrome…”
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Immune Checkpoints and CAR-T Cells: The Pioneers in Future Cancer Therapies? by Hosseinkhani, Negar, Derakhshani, Afshin, Kooshkaki, Omid, Abdoli Shadbad, Mahdi, Hajiasgharzadeh, Khalil, Baghbanzadeh, Amir, Safarpour, Hossein, Mokhtarzadeh, Ahad, Brunetti, Oronzo, Yue, Simon C, Silvestris, Nicola, Baradaran, Behzad

“…Although the ever-increasing number of cancer patients pose substantial challenges worldwide, finding a treatment with the highest response rate and the lowest…”
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MiR-144: A New Possible Therapeutic Target and Diagnostic/Prognostic Tool in Cancers by Kooshkaki, Omid, Rezaei, Zohre, Rahmati, Meysam, Vahedi, Parviz, Derakhshani, Afshin, Brunetti, Oronzo, Baghbanzadeh, Amir, Mansoori, Behzad, Silvestris, Nicola, Baradaran, Behzad

“…MicroRNAs (miRNAs) are small and non-coding RNAs that display aberrant expression in the tissue and plasma of cancer patients when tested in comparison to…”
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The Positive and Negative Immunoregulatory Role of B7 Family: Promising Novel Targets in Gastric Cancer Treatment by Bolandi, Nadia, Derakhshani, Afshin, Hemmat, Nima, Baghbanzadeh, Amir, Asadzadeh, Zahra, Afrashteh Nour, Mina, Brunetti, Oronzo, Bernardini, Renato, Silvestris, Nicola, Baradaran, Behzad

“…Gastric cancer (GC), with a heterogeneous nature, is the third leading cause of death worldwide. Over the past few decades, stable reductions in the incidence…”
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Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review by Ghaseminejad-Raeini, Amirhossein, Ghaderi, Ali, Sharafi, Amirmohammad, Nematollahi-Sani, Behrad, Moossavi, Maryam, Derakhshani, Afshin, Sarab, Gholamreza Anani

“…For many years, vitamin D has been acknowledged for its role in maintaining calcium and phosphate balance. However, in recent years, research has assessed its…”
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Deep learning applications in single-cell genomics and transcriptomics data analysis by Erfanian, Nafiseh, Heydari, A. Ali, Feriz, Adib Miraki, Iañez, Pablo, Derakhshani, Afshin, Ghasemigol, Mohammad, Farahpour, Mohsen, Razavi, Seyyed Mohammad, Nasseri, Saeed, Safarpour, Hossein, Sahebkar, Amirhossein

“…Traditional bulk sequencing methods are limited to measuring the average signal in a group of cells, potentially masking heterogeneity, and rare populations…”
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COVID-19 Infection in Cancer Patients: How Can Oncologists Deal With These Patients? by Brunetti, Oronzo, Derakhshani, Afshin, Baradaran, Behzad, Galvano, Antonio, Russo, Antonio, Silvestris, Nicola

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From Oncogenic Signaling Pathways to Single-Cell Sequencing of Immune Cells: Changing the Landscape of Cancer Immunotherapy by Derakhshani, Afshin, Rostami, Zeinab, Safarpour, Hossein, Shadbad, Mahdi Abdoli, Nourbakhsh, Niloufar Sadat, Argentiero, Antonella, Taefehshokr, Sina, Tabrizi, Neda Jalili, Kooshkaki, Omid, Astamal, Reza Vaezi, Singh, Pankaj Kumar, Taefehshokr, Nima, Alizadeh, Nazila, Silvestris, Nicola, Baradaran, Behzad

“…Over the past decade, there have been remarkable advances in understanding the signaling pathways involved in cancer development. It is well-established that…”
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The Role of V-Domain Ig Suppressor of T Cell Activation (VISTA) in Cancer Therapy: Lessons Learned and the Road Ahead by Hosseinkhani, Negar, Derakhshani, Afshin, Shadbad, Mahdi Abdoli, Argentiero, Antonella, Racanelli, Vito, Kazemi, Tohid, Mokhtarzadeh, Ahad, Brunetti, Oronzo, Silvestris, Nicola, Baradaran, Behzad

“…Immune checkpoints (ICs) have pivotal roles in regulating immune responses. The inhibitory ICs in the tumor microenvironment (TME) have been implicated in the…”
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From Melanoma Development to RNA-Modified Dendritic Cell Vaccines: Highlighting the Lessons From the Past by Shadbad, Mahdi Abdoli, Hajiasgharzadeh, Khalil, Derakhshani, Afshin, Silvestris, Nicola, Baghbanzadeh, Amir, Racanelli, Vito, Baradaran, Behzad

“…Although melanoma remains the deadliest skin cancer, the current treatment has not resulted in the desired outcomes. Unlike chemotherapy, immunotherapy has…”
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Pancreatic Cancer Signaling Pathways, Genetic Alterations, and Tumor Microenvironment: The Barriers Affecting the Method of Treatment by Javadrashid, Darya, Baghbanzadeh, Amir, Derakhshani, Afshin, Leone, Patrizia, Silvestris, Nicola, Racanelli, Vito, Solimando, Antonio Giovanni, Baradaran, Behzad

“…Genetic alterations, especially the K-Ras mutation, carry the heaviest burden in the progression of pancreatic precursor lesions into pancreatic ductal…”
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Silencing ZEB2 Induces Apoptosis and Reduces Viability in Glioblastoma Cell Lines by Safaee, Sahar, Fardi, Masoumeh, Hemmat, Nima, Khosravi, Neda, Derakhshani, Afshin, Silvestris, Nicola, Baradaran, Behzad

“…Glioma is an aggressive type of brain tumor that originated from neuroglia cells, accounts for about 80% of all malignant brain tumors. Glioma aggressiveness…”
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Targeted Therapy of B7 Family Checkpoints as an Innovative Approach to Overcome Cancer Therapy Resistance: A Review from Chemotherapy to Immunotherapy by Amir Taghavi, Bita, Alizadeh, Nazila, Saeedi, Hossein, Karim Ahangar, Noora, Derakhshani, Afshin, Hajiasgharzadeh, Khalil, Silvestris, Nicola, Baradaran, Behzad, Brunetti, Oronzo

“…It is estimated that there were 18.1 million cancer cases worldwide in 2018, with about 9 million deaths. Proper diagnosis of cancer is essential for its…”
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The cross-talk between tumor-associated macrophages and tumor endothelium: Recent advances in macrophage-based cancer immunotherapy by Baradaran, Ali, Asadzadeh, Zahra, Hemmat, Nima, Baghbanzadeh, Amir, Shadbad, Mahdi Abdoli, Khosravi, Neda, Derakhshani, Afshin, Alemohammad, Hajar, Afrashteh Nour, Mina, Safarpour, Hossein, Silvestris, Nicola, Brunetti, Oronzo, Baradaran, Behzad

“…Tumor-associated macrophages (TAMs) are among the abundant cell populations of the tumor microenvironment (TME), which have pivotal roles in tumor development,…”
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Exploiting systems biology to investigate the gene modules and drugs in ovarian cancer: A hypothesis based on the weighted gene co-expression network analysis by Nomiri, Samira, Karami, Hassan, Baradaran, Behzad, Javadrashid, Darya, Derakhshani, Afshin, Nourbakhsh, Niloufar Sadat, Shadbad, Mahdi Abdoli, Solimando, Antonio Giovanni, Tabrizi, Neda Jalili, Brunetti, Oronzo, Nasseri, Saeed, Racanelli, Vito, Safarpour, Hossein, Silvestris, Nicola

“…Ovarian cancer (OC) is one of the worrisome gynecological cancers worldwide. Given its considerable mortality rate, it is necessary to investigate its…”
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The Latest Findings of PD-1/PD-L1 Inhibitor Application in Gynecologic Cancers by Kooshkaki, Omid, Derakhshani, Afshin, Safarpour, Hossein, Najafi, Souzan, Vahedi, Parviz, Brunetti, Oronzo, Torabi, Mitra, Lotfinejad, Parisa, Paradiso, Angelo Virgilio, Racanelli, Vito, Silvestris, Nicola, Baradaran, Behzad

“…Gynecologic cancers account for approximately 11% of the newly diagnosed cancers in women in the United States and for 18% globally. The presence of…”
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