Search Results - "Depolo, N."

VSV-G Pseudotyped Lentiviral Vector Particles Produced in Human Cells Are Inactivated by Human Serum by DePolo, Nicholas J., Reed, Joyce D., Sheridan, Philip L., Townsend, Kay, Sauter, Sybille L., Jolly, Douglas J., Dubensky, Thomas W.

“…Lentiviral vectors transduce dividing and postmitotic cells and thus are being developed toward therapies for many diseases affecting diverse tissues. One…”
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Continuing coevolution of virus and defective interfering particles and of viral genome sequences during undiluted passages: virus mutants exhibiting nearly complete resistance to formerly dominant defective interfering particles by DEPOLO, N. J, GIACHETTI, C, HOLLAND, J. J

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Generation of Retroviral Packaging and Producer Cell Lines for Large-Scale Vector Production and Clinical Application: Improved Safety and High Titer by Sheridan, Philip L., Bodner, Mordechai, Lynn, Andrea, Phuong, Trung K., DePolo, Nicholas J., de la Vega, Daniel J., O'Dea, Joanne, Nguyen, Kathy, McCormack, James E., Driver, David A., Townsend, Kay, Ibañez, Carlos E., Sajjadi, Nancy C., Greengard, Judith S., Moore, Margaret D., Respess, James, Chang, Stephen M.W., Dubensky, Thomas W., Jolly, Douglas J., Sauter, Sybille L.

“…For many applications, human clinical therapies using retroviral vectors still require many technological improvements in key areas of vector design and…”
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The Resistance of Retroviral Vectors Produced from Human Cells to Serum Inactivation In Vivo and In Vitro Is Primate Species Dependent by DePolo, N J, Harkleroad, C E, Bodner, M, Watt, A T, Anderson, C G, Greengard, J S, Murthy, K K, Dubensky, Jr, T W, Jolly, D J

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Aphidicolin-resistant polyomavirus and subgenomic cellular DNA synthesis occur early in the differentiation of cultured myoblasts to myotubes by DEPOLO, N. J, VILLARREAL, L. P

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E1A represses wild-type and F9-selected polyomavirus DNA replication by a mechanism not requiring depression of large tumor antigen transcription by DEPOLO, N. J, VILLARREAL, L. P

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Very Rapid Generation/Amplification of Defective Interfering Particles by Vesicular Stomatitis Virus Variants Isolated from Persistent Infection by Depolo, Nicholas J, Holland, John J

“…Department of Biology, University of California at San Diego, La Jolla, California 92093, U.S.A. Multiply cloned variants of vesicular stomatitis virus (VSV)…”
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Evaluation of PCR and ELISA assays for screening clinical trial subjects for replication-competent retrovirus by Martineau, D, Klump, W M, McCormack, J E, DePolo, N J, Kamantigue, E, Petrowski, M, Hanlon, J, Jolly, D J, Mento, S J, Sajjadi, N

“…Gene delivery via murine-based recombinant retroviral vectors is currently widely used in gene therapy clinical trials. The vectors are engineered to be…”
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Anti-vector immunoglobulin induced by retroviral vectors by McCormack, J E, Martineau, D, DePolo, N, Maifert, S, Akbarian, L, Townsend, K, Lee, W, Irwin, M, Sajjadi, N, Jolly, D J, Warner, J

“…Replication-incompetent retroviruses have been employed as gene therapy vectors in experimental settings for more than a decade. More recently, these vectors…”
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The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance--a review by Domingo, E, Martínez-Salas, E, Sobrino, F, de la Torre, J C, Portela, A, Ortín, J, López-Galindez, C, Pérez-Breña, P, Villanueva, N, Nájera, R

“…We review evidence that cloned (or uncloned) populations of most RNA viruses do not consist of a single genome species of defined sequence, but rather of…”
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The intracellular half-lives of nonreplicating nucleocapsids of DI particles of wild type and mutant strains of vesicular stomatitis virus by DePolo, N J, Holland, J J

“…We have used defective interfering (DI) particles purified free of all infectious virus to determine the intracellular biological stability of nonreplicating…”
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A drift-free hyperbolic encoder by Depolo, N.

“…THIS PAPER will discuss stabilization problems in an audio-signal hyperbolic encoder developed for a pcm telephone multiplexing system*…”
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Very rapid generation/amplification of defective interfering particles by vesicular stomatitis virus variants isolated from persistent infection by Depolo, N J, Holland, J J

“…Multiply cloned variants of vesicular stomatitis virus (VSV) were found to generate/amplify defective interfering (DI) particles at a rate greatly exceeding…”
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