Search Results - "Depaola, Natacha"

Specificity in the participation of connexin proteins in flow-induced endothelial gap junction communication by Ebong, Eno E., DePaola, Natacha

“…Endothelial cell (EC) dysfunction and atherosclerotic plaque formation coincide with human circulatory regions where blood flow is altered (disturbed). In…”
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Spatial and Temporal Regulation of Gap Junction Connexin43 in Vascular Endothelial Cells Exposed to Controlled Disturbed Flows in vitro by DePaola, Natacha, Davies, Peter F., Pritchard, William F., Florez, Lucio, Harbeck, Nadeene, Polacek, Denise C.

“…Hemodynamic regulation of the endothelial gap junction protein connexin43 (Cx43) was studied in a model of controlled disturbed flows in vitro. Cx43 mRNA,…”
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Flow regulates intercellular communication in HAEC by assembling functional Cx40 and Cx37 gap junctional channels by Ebong, Eno Essien, Kim, Sanghee, DePaola, Natacha

“…Direct cell-to-cell transfer of ions and small signaling molecules via gap junctions plays a key role in vessel wall homeostasis. Vascular endothelial gap…”
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Spatial variations in endothelial barrier function in disturbed flows in vitro by Phelps, J E, DePaola, N

“…Hindered barrier function has been implicated in the initiation and progression of atherosclerosis, a disease of focal nature associated with altered…”
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Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction by Davies, P F, Barbee, K A, Volin, M V, Robotewskyj, A, Chen, J, Joseph, L, Griem, M L, Wernick, M N, Jacobs, E, Polacek, D C, dePaola, N, Barakat, A I

“…Blood flow interactions with the vascular endothelium represent a specialized example of mechanical regulation of cell function that has important…”
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Shear Stress-Mediated Cytoskeletal Remodeling and Cortactin Translocation in Pulmonary Endothelial Cells by Birukov, Konstantin G, Birukova, Anna A, Dudek, Steven M, Verin, Alexander D, Crow, Michael T, Zhan, Xi, DePaola, Natacha, Garcia, Joe G. N

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Electrical impedance of cultured endothelium under fluid flow by DePaola, N, Phelps, J E, Florez, L, Keese, C R, Minnear, F L, Giaever, I, Vincent, P

“…The morphological and functional status of organs, tissues, and cells can be assessed by evaluating their electrical impedance. Fluid shear stress regulates…”
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Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro by Rizzo, Victor, Morton, Christine, DePaola, Natacha, Schnitzer, Jan E, Davies, Peter F

“…The luminal surface of rat lung microvascular endothelial cells in situ is sensitive to changing hemodynamic parameters. Acute mechanosignaling events…”
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Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells by Shikata, Yasushi, Rios, Alexander, Kawkitinarong, Kamon, DePaola, Natacha, Garcia, Joe G.N., Birukov, Konstantin G.

“…Regulation of endothelial cell (EC) permeability by bioactive molecules is associated with specific patterns of cytoskeletal and cell contact remodeling. A…”
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Flow-conditioned HUVECs support clustered leukocyte adhesion by coexpressing ICAM-1 and E-selectin by Burns, Michael P, DePaola, Natacha

“…Endothelial sequestration of circulating monocytes is a key event in early atherosclerosis. Hemodynamics is proposed to regulate monocyte-endothelial cell…”
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Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells by Birukov, Konstantin G, Birukova, Anna A, Dudek, Steven M, Verin, Alexander D, Crow, Michael T, Zhan, Xi, DePaola, Natacha, Garcia, Joe G N

“…Hemodynamic forces in the form of shear stress (SS) and mechanical strain imposed by circulating blood are recognized factors involved in the control of…”
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Hemodynamics and the focal origin of atherosclerosis: a spatial approach to endothelial structure, gene expression, and function by Davies, P F, Shi, C, Depaola, N, Helmke, B P, Polacek, D C

“…Atherosclerosis originates at predictable focal and regional sites that are associated with complex flow disturbances and flow separations in large arteries…”
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Generation of cell-derived three dimensional extracellular matrix substrates from two dimensional endothelial cell cultures by Zwolinski, Christopher M, Ellison, Karen S, Depaola, Natacha, Thompson, Deanna M

“…Within the cellular microenvironment, extracellular matrix (ECM) proteins are critical nonsoluble signaling factors that modulate cell attachment, migration,…”
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A spatial approach to transcriptional profiling: mechanotransduction and the focal origin of atherosclerosis by Davies, Peter F, Polacek, Denise C, Handen, Jeffrey S, Helmke, Brian P, DePaola, Natacha

“…The initiation and progression of focal atherosclerotic lesions has long been known to be associated with regions of disturbed blood flow. Improved precision…”
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Static magnetic fields in the regulation of bone cell function and cell differentiation by Leventis, Katerina

“…The prevalence of musculoskeletal disorders renders a better understanding of the cellular processes and therapies equipped to manage the condition and enhance…”
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The effects of flow on adhesion molecule expression and monocyte-endothelial interactions in vitro by Abueg, Ellaine

“…Atherosclerosis is a cardiovascular disease that can have fatal complications, such as a heart attack or stroke. A key event in early lesion development is…”
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Hemodynamics and the Focal Origin of Atherosclerosis by DAVIES, PETER F., SHI, CONGZHU, DePAOLA, NATACHA, HELMKE, BRIAN P., POLACEK, DENISE C.

“…: Atherosclerosis originates at predictable focal and regional sites that are associated with complex flow disturbances and flow separations in large arteries…”
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Shear stress gradients (SSG) regulate endothelial permeability to macromolecules in vitro by Depaola, Natacha, Phelps, Jeffrey E

“…An in vitro transport assay was developed whereby fluorescent macromolecules permeating the cell layer were caught in a subluminal gel creating a record of the…”
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Spatial approach to gene expression in endothelial mechanotransduction by Davies, Peter, Shi, Congzhu, DePaola, Natacha, Polacek, Denise

“…To obtain sufficient material from isolated cells, a technique was used that amplified antisense RNA in a near linear manner. The labeled aRNA or its cDNA was…”
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Exposure of bladder smooth muscle cells to mechanical strain and sustained hydrostatic pressure promotes upregulation of HB-EGF and collagen type III by Haberstroh, Karen, Kaefer, Martin, Depaola, Natacha, Bizios, Rena

“…The novel Hydrostrain system was designed to establish and maintain conditions that simulate the in vivo mechanical environment of the bladder. In this system,…”
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