Search Results - "Depaola, N"

Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells by Shikata, Yasushi, Rios, Alexander, Kawkitinarong, Kamon, DePaola, Natacha, Garcia, Joe G.N., Birukov, Konstantin G.

“…Regulation of endothelial cell (EC) permeability by bioactive molecules is associated with specific patterns of cytoskeletal and cell contact remodeling. A…”
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Electrical impedance of cultured endothelium under fluid flow by DePaola, N, Phelps, J E, Florez, L, Keese, C R, Minnear, F L, Giaever, I, Vincent, P

“…The morphological and functional status of organs, tissues, and cells can be assessed by evaluating their electrical impedance. Fluid shear stress regulates…”
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Theme I: the endothelium and smooth muscle in hypertension : Hemodynamic regulation of endothelial communication by DePaola, N., Polacek, D.C., Davies, P.F.

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Mechanical forces alter growth factor release by pleural mesothelial cells by Waters, C M, Chang, J Y, Glucksberg, M R, DePaola, N, Grotberg, J B

“…The mesothelial cells that form the visceral pleura of the lung are subjected to physical forces such as stretch due to lung expansion and fluid shear stress…”
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Shear stress alters pleural mesothelial cell permeability in culture by Waters, C M, Glucksberg, M R, Depaola, N, Chang, J, Grotberg, J B

“…The sliding motion of the lung against the chest wall creates a shear stress in the pleural space, which can be as high as 60 dyn/cm2, depending on the…”
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Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro by Rizzo, Victor, Morton, Christine, DePaola, Natacha, Schnitzer, Jan E, Davies, Peter F

“…The luminal surface of rat lung microvascular endothelial cells in situ is sensitive to changing hemodynamic parameters. Acute mechanosignaling events…”
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Neural stem cell response to endothelial-derived extracellular matrix produced by hemodynamically stimulated endothelial cells by Ellison, K S, Zwolinski, C M, Newman, M R, DePaola, N, Thompson, D M

“…This study demonstrates that adult neural stem cells (NSC) exhibit a differential response to endothelial cell (EC) derived extracellular matrix (ECM) produced…”
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Flow-conditioned HUVECs support clustered leukocyte adhesion by coexpressing ICAM-1 and E-selectin by Burns, Michael P, DePaola, Natacha

“…Endothelial sequestration of circulating monocytes is a key event in early atherosclerosis. Hemodynamics is proposed to regulate monocyte-endothelial cell…”
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Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells by Birukov, Konstantin G, Birukova, Anna A, Dudek, Steven M, Verin, Alexander D, Crow, Michael T, Zhan, Xi, DePaola, Natacha, Garcia, Joe G N

“…Hemodynamic forces in the form of shear stress (SS) and mechanical strain imposed by circulating blood are recognized factors involved in the control of…”
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Adsorption of proteins out of plasma onto glass from a separated flow by Leduc, C, Depaola, N, Konath, S, Vroman, L, Leonard, E F

“…Perturbations in the adsorption of plasma proteins caused by flow separation were studied quantitatively. An instrument was constructed that causes flow to…”
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Spatial and Temporal Regulation of Gap Junction Connexin43 in Vascular Endothelial Cells Exposed to Controlled Disturbed Flows in vitro by DePaola, Natacha, Davies, Peter F., Pritchard, William F., Florez, Lucio, Harbeck, Nadeene, Polacek, Denise C.

“…Hemodynamic regulation of the endothelial gap junction protein connexin43 (Cx43) was studied in a model of controlled disturbed flows in vitro. Cx43 mRNA,…”
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Flow regulates intercellular communication in HAEC by assembling functional Cx40 and Cx37 gap junctional channels by Ebong, Eno Essien, Kim, Sanghee, DePaola, Natacha

“…Direct cell-to-cell transfer of ions and small signaling molecules via gap junctions plays a key role in vessel wall homeostasis. Vascular endothelial gap…”
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Hemodynamics and the focal origin of atherosclerosis: a spatial approach to endothelial structure, gene expression, and function by Davies, P F, Shi, C, Depaola, N, Helmke, B P, Polacek, D C

“…Atherosclerosis originates at predictable focal and regional sites that are associated with complex flow disturbances and flow separations in large arteries…”
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Vascular endothelium responds to fluid shear stress gradients by DEPAOLA, N, GIMBRONE, M. A, DAVIES, P. F, FORBES DEWEY, C. JR

“…In vitro investigations of the responses of vascular endothelium to fluid shear stress have typically been conducted under conditions where the time-mean shear…”
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Spatial variations in endothelial barrier function in disturbed flows in vitro by Phelps, J E, DePaola, N

“…Hindered barrier function has been implicated in the initiation and progression of atherosclerosis, a disease of focal nature associated with altered…”
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Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction by Davies, P F, Barbee, K A, Volin, M V, Robotewskyj, A, Chen, J, Joseph, L, Griem, M L, Wernick, M N, Jacobs, E, Polacek, D C, dePaola, N, Barakat, A I

“…Blood flow interactions with the vascular endothelium represent a specialized example of mechanical regulation of cell function that has important…”
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Generation of cell-derived three dimensional extracellular matrix substrates from two dimensional endothelial cell cultures by Zwolinski, Christopher M, Ellison, Karen S, Depaola, Natacha, Thompson, Deanna M

“…Within the cellular microenvironment, extracellular matrix (ECM) proteins are critical nonsoluble signaling factors that modulate cell attachment, migration,…”
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A spatial approach to transcriptional profiling: mechanotransduction and the focal origin of atherosclerosis by Davies, Peter F, Polacek, Denise C, Handen, Jeffrey S, Helmke, Brian P, DePaola, Natacha

“…The initiation and progression of focal atherosclerotic lesions has long been known to be associated with regions of disturbed blood flow. Improved precision…”
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Thursday, May 20, Astor Ballroom, 10:30 AM: Theme I: The endothelium and smooth muscle in hypertension by DePaola, N., Polacek, D.C., Davies, P.F.

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4.W19.1 Hemodynamic forces and vascular cell communication by Davies, P.F., DePaola, N., Polacek, D.C.

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