Search Results - "Deota, Shaunak"

Identification of a Tissue-Restricted Isoform of SIRT1 Defines a Regulatory Domain that Encodes Specificity by Deota, Shaunak, Chattopadhyay, Tandrika, Ramachandran, Deepti, Armstrong, Eric, Camacho, Beatriz, Maniyadath, Babukrishna, Fulzele, Amit, Gonzalez-de-Peredo, Anne, Denu, John M., Kolthur-Seetharam, Ullas

“…The conserved NAD+-dependent deacylase SIRT1 plays pivotal, sometimes contrasting, roles in diverse physiological and pathophysiological conditions. In this…”
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SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK by Ho, Linh, Titus, Allen Sam, Banerjee, Kushal Kr, George, Suji, Lin, Wei, Deota, Shaunak, Saha, Asish K., Nakamura, Ken, Gut, Philipp, Verdin, Eric, Kolthur-Seetharam, Ullas

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Aligning mealtimes to live longer by Deota, Shaunak, Panda, Satchidananda

“…Calorie restriction, fasting, and circadian rhythms sync together for a long, healthy life in mice…”
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New Horizons: Circadian Control of Metabolism Offers Novel Insight Into the Cause and Treatment of Metabolic Diseases by Deota, Shaunak, Panda, Satchidananda

“…Abstract Metabolic homeostasis is achieved by endocrine factors, signaling cascades, and metabolic pathways that sense and respond to metabolic demands in…”
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Sex- and age-dependent outcomes of 9-hour time-restricted feeding of a Western high-fat high-sucrose diet in C57BL/6J mice by Chaix, Amandine, Deota, Shaunak, Bhardwaj, Raghav, Lin, Terry, Panda, Satchidananda

“…Time-restricted feeding (TRF) is a nutritional intervention wherein food intake is limited to a consistent 8- to 10-h daily window without changes in…”
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Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals by Deota, Shaunak, Lin, Terry, Chaix, Amandine, Williams, April, Le, Hiep, Calligaro, Hugo, Ramasamy, Ramesh, Huang, Ling, Panda, Satchidananda

“…Time-restricted feeding (TRF) is an emerging behavioral nutrition intervention that involves a daily cycle of feeding and fasting. In both animals and humans,…”
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Multi-organ transcriptome atlas of a mouse model of relative energy deficiency in sport by van Rosmalen, Laura, Zhu, Jiaoyue, Maier, Geraldine, Gacasan, Erica G, Lin, Terry, Zhemchuzhnikova, Elena, Rothenberg, Vince, Razu, Swithin, Deota, Shaunak, Ramasamy, Ramesh K, Sah, Robert L, McCulloch, Andrew D, Hut, Roelof A, Panda, Satchidananda

“…Insufficient energy intake to meet energy expenditure demands of physical activity can result in systemic neuroendocrine and metabolic abnormalities in…”
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Energy balance drives diurnal and nocturnal brain transcriptome rhythms by van Rosmalen, Laura, Deota, Shaunak, Maier, Geraldine, Le, Hiep D., Lin, Terry, Ramasamy, Ramesh K., Hut, Roelof A., Panda, Satchidananda

“…Plasticity in daily timing of activity has been observed in many species, yet the underlying mechanisms driving nocturnality and diurnality are unknown. By…”
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SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK by Ho, Linh, Titus, Allen Sam, Banerjee, Kushal Kr, George, Suji, Lin, Wei, Deota, Shaunak, Saha, Asish K, Nakamura, Ken, Gut, Philipp, Verdin, Eric, Kolthur-Seetharam, Ullas

“…Efficient coupling of cellular energy production to metabolic demand is crucial to maintain organismal homeostasis. Here, we report that the mitochondrial…”
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Allosteric Regulation of Cyclin-B Binding by the Charge State of Catalytic Lysine in CDK1 Is Essential for Cell-Cycle Progression by Deota, Shaunak, Rathnachalam, Sivasudhan, Namrata, Kanojia, Boob, Mayank, Fulzele, Amit, Radhika, S., Ganguli, Shubhra, Balaji, Chinthapalli, Kaypee, Stephanie, Vishwakarma, Krishna Kant, Kundu, Tapas Kumar, Bhandari, Rashna, Gonzalez de Peredo, Anne, Mishra, Mithilesh, Venkatramani, Ravindra, Kolthur-Seetharam, Ullas

“…Cyclin-dependent kinase 1 (CDK1) is essential for cell-cycle progression. While dependence of CDK activity on cyclin levels is well established, molecular…”
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Spatio-Temporal Control of Cellular and Organismal Physiology by Sirtuins by Deota, Shaunak, Shukla, Namrata, Kolthur-Seetharam, Ullas

“…The survival of an organism is intricately dependent upon its ability to sense and respond to both extracellular and intracellular cues. In the context of…”
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Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients by Lam, Michael Tun Yin, Duttke, Sascha H., Odish, Mazen F., Le, Hiep D., Hansen, Emily A., Nguyen, Celina T., Trescott, Samantha, Kim, Roy, Deota, Shaunak, Chang, Max W., Patel, Arjun, Hepokoski, Mark, Alotaibi, Mona, Rolfsen, Mark, Perofsky, Katherine, Warden, Anna S., Foley, Jennifer, Ramirez, Sydney I., Dan, Jennifer M., Abbott, Robert K., Crotty, Shane, Crotty Alexander, Laura E., Malhotra, Atul, Panda, Satchidananda, Benner, Christopher W., Coufal, Nicole G.

“…Transcription factor programs mediating the immune response to coronavirus disease 2019 (COVID-19) are not fully understood. Capturing active transcription…”
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