Search Results - "Dent, Jo"

A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences by Shaaban, Abeer M., Ball, Graham R., Brannan, Rebecca A., Cserni, Gabor, Benedetto, Anna Di, Dent, Jo, Fulford, Laura, Honarpisheh, Helen, Jordan, Lee, Jones, J. Louise, Kanthan, Rani, Maraqa, Loaie, Litwiniuk, Maria, Mottolese, Marcella, Pollock, Steven, Provenzano, Elena, Quinlan, Philip R., Reall, Georgina, Shousha, Sami, Stephens, Mark, Verghese, Eldo T., Walker, Rosemary A., Hanby, Andrew M., Speirs, Valerie

“…Male breast cancer remains understudied despite evidence of rising incidence. Using a co-ordinated multi-centre approach, we present the first large scale…”
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A UK prospective multicentre decision impact, decision conflict and economic evaluation of the 21-gene assay in women with node+ve, hormone receptor+ve, HER2-ve breast cancer by Holt, Simon, Verrill, Mark, Pettit, Laura, Rigg, Anna, Hickish, Tamas, Archer, Caroline, Dent, Jo, Dillon, Marianne, Nathan, Mark, Barthelmes, Ludger, Rehman, Shazza, Sharaiha, Yousef, Innis, Paige, Sai-Giridhar, Priya, Khawaja, Saira

“…Background For a tumour profiling test to be of value, it needs to demonstrate that it is changing clinical decisions, improving clinical confidence, and of…”
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Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial by Hall, Peter S, Swinson, Daniel, Cairns, David A, Waters, Justin S, Petty, Russell, Allmark, Christine, Ruddock, Sharon, Falk, Stephen, Wadsley, Jonathan, Roy, Rajarshi, Tillett, Tania, Nicoll, Jonathan, Cummins, Sebastian, Mano, Joseph, Grumett, Simon, Stokes, Zuzana, Kamposioras, Konstantinos-Velios, Chatterjee, Anirban, Garcia, Angel, Waddell, Tom, Guptal, Kamalnayan, Maisey, Nick, Khan, Mohammed, Dent, Jo, Lord, Simon, Crossley, Ann, Katona, Eszter, Marshall, Helen, Grabsch, Heike I, Velikova, Galina, Ow, Pei Loo, Handforth, Catherine, Howard, Helen, Seymour, Matthew T

“…Older and/or frail patients are underrepresented in landmark cancer trials. Tailored research is needed to address this evidence gap. The GO2 randomized…”
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Characterisation of male breast cancer: a descriptive biomarker study from a large patient series by Humphries, Matthew P., Sundara Rajan, Sreekumar, Honarpisheh, Hedieh, Cserni, Gabor, Dent, Jo, Fulford, Laura, Jordan, Lee B., Jones, J. Louise, Kanthan, Rani, Litwiniuk, Maria, Di Benedetto, Anna, Mottolese, Marcella, Provenzano, Elena, Shousha, Sami, Stephens, Mark, Kulka, Janina, Ellis, Ian O., Titloye, Akinwale N., Hanby, Andrew M., Shaaban, Abeer M., Speirs, Valerie

“…Male breast cancer (MBC) is rare. We assembled 446 MBCs on tissue microarrays and assessed clinicopathological information, together with data from 15…”
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Abstract OT3-17-03: Impact of the Oncotype DX breast cancer assay on treatment decisions in a UK population of patients with oestrogen receptor positive early breast cancer with 1-3 lymph nodes positive who are candidates for chemotherapy, but for whom the benefits are uncertain - Interim results by Thomas, Daniel, Maxwell, William, Archer, Caroline, Rigg, Anne, Hickish, Tamas, Dent, Jo, Pettit, Laura, Dillon, Marianne, Goldsmith, Christy, Verrill, Mark, Barthelmes, Ludger, Khawaja, Saira, Sharaiha, Yousef, Davies, Mark, Arikat, Fawaz, Khan, Sahail, Munir, Asma, Huws, Anita, Holt, Simon DavidHenry

“…Abstract Introduction: The addition of adjuvant chemotherapy to hormonal therapy is recommended for patients with lymph node-positive (LN+ve), estrogen…”
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Best supportive care (BSC) with or without low-dose chemotherapy (chemo) in frail elderly patients with advanced gastroesophageal cancer (aGOAC): The uncertain randomization of the GO2 phase III trial by Swinson, Daniel, Hingorani, Mohan, Stokes, Zuzana, Dent, Jo, Guptal, Kamalnayan, Chatterjee, Anirban, Kamposioras, Konstantinos, Grumett, Simon Aird, Khan, Mohammad, Marshall, Helen, Ruddock, Sharon, Allmark, Christine, Katona, Eszter, Howard, Helen C, Velikova, Galina, Lord, Simon, Hall, Peter S, Seymour, Matthew T.

“…Abstract only 4051 Background: Before 2000, trials comparing BSC +/- chemo for aGOAC showed overall survival (OS) benefit, but in predominantly fit patients…”
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Abstract P6-01-11: A UK prospective multicentre decision impact, decision conflict and economic evaluation of the use of Oncotype DX® to guide chemotherapy in 680 women with hormone receptor positive, HER2 negative breast cancer and 1 to 3 nodes involved by Holt, Simon D., Sai-Giridhar, Priyadharshini, Verrill, Mark, Pettit, Laura, Rigg, Anna, Hickish, Tamas, Archer, Caroline D., Wadhawan, Anshu, Dillon, Marianne, Dent, Jo, Nathan, Mark R., Barthelmes, Ludger, rehman, Shazza, Innis, Paige, Khawaja, Saira

“…Abstract Introduction: For a test to be of value, it needs to demonstrate that it is changing clinical decisions, improving clinical confidence and of economic…”
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A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer by Humphries, Matthew P, Sundara Rajan, Sreekumar, Droop, Alastair, Suleman, Charlotte A B, Carbone, Carmine, Nilsson, Cecilia, Honarpisheh, Hedieh, Cserni, Gabor, Dent, Jo, Fulford, Laura, Jordan, Lee B, Jones, J Louise, Kanthan, Rani, Litwiniuk, Maria, Di Benedetto, Anna, Mottolese, Marcella, Provenzano, Elena, Shousha, Sami, Stephens, Mark, Walker, Rosemary A, Kulka, Janina, Ellis, Ian O, Jeffery, Margaret, Thygesen, Helene H, Cappelletti, Vera, Daidone, Maria G, Hedenfalk, Ingrid A, Fjällskog, Marie-Louise, Melisi, Davide, Stead, Lucy F, Shaaban, Abeer M, Speirs, Valerie

“…Breast cancer affects both genders, but is understudied in men. Although still rare, male breast cancer (MBC) is being diagnosed more frequently. Treatments…”
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Three, two, or one drug chemotherapy for frail or elderly patients with advanced gastroesophageal cancer (321GO): A feasibility study by Hall, Peter S., Lord, Simon, Collinson, Michelle, Marshall, Helen, Jones, Marc, Olivier, Catherine, Howard, Helen, Seligman, Jenny, Swinson, Daniel, Roy, Rajarshi, Dent, Jo, Cheeseman, Sue, Last, Kim William, Seymour, Matthew T.

“…Abstract only 97 Background: The median age of death from gastroesophageal (GO) cancer is 77 years. Palliative chemotherapy can improve survival and quality of…”
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Supportive care after breast cancer surgery by Allinson, Veronica M, Dent, Jo

“…Routine follow-up after treatment for breast cancer aims to monitor for recurrence, manage late effects of treatment and give patients information, support and…”
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