Search Results - "Denslow, Nancy D"

Comparison of Molecular and Histological Changes in Zebrafish Gills Exposed to Metallic Nanoparticles by Griffitt, Robert J., Hyndman, Kelly, Denslow, Nancy D., Barber, Davis S.

“…Research has demonstrated that metallic nanoparticles produce toxicity in aquatic organisms that is due largely to effects of particulates as opposed to…”
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Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology by Groh, Ksenia J., Carvalho, Raquel N., Chipman, James K., Denslow, Nancy D., Halder, Marlies, Murphy, Cheryl A., Roelofs, Dick, Rolaki, Alexandra, Schirmer, Kristin, Watanabe, Karen H.

“…•AOP development can improve understanding and predicting chronic toxicity outcomes.•Chemical- and site-specific risk assessment requires extension of the AOP…”
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Untargeted lipidomics reveals the toxicity of bisphenol A bis(3-chloro-2- hydroxypropyl) ether and bisphenols A and F in zebrafish liver cells by Marqueño, Anna, Pérez-Albaladejo, Elisabet, Denslow, Nancy D., Bowden, John A., Porte, Cinta

“…Given the opposing responses reported for bisphenol A (BPA) in terms of induction of obesogenic effects and impaired lipid metabolism, the increasing use of…”
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Quercetin, a natural product supplement, impairs mitochondrial bioenergetics and locomotor behavior in larval zebrafish (Danio rerio) by Zhang, Ji-Liang, Laurence Souders, Christopher, Denslow, Nancy D., Martyniuk, Christopher J.

“…Quercetin is a natural product that is sold as a supplement in health food stores. While there are reported benefits for this flavonoid as a dietary supplement…”
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Steroid hormones and estrogenic activity in the wastewater outfall and receiving waters of the Chascomús chained shallow lakes system (Argentina) by González, Anelisa, Kroll, Kevin J., Silva-Sanchez, Cecilia, Carriquiriborde, Pedro, Fernandino, Juan I., Denslow, Nancy D., Somoza, Gustavo M.

“…Natural and synthetic steroid hormones, excreted by humans and farmed animals, have been considered as important sources of environmental endocrine disruptors…”
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Quantification of steroid hormones in low volume plasma and tissue homogenates of fish using LC-MS/MS by Nouri, Mohammad-Zaman, Kroll, Kevin J., Webb, Molly, Denslow, Nancy D.

“…•A panel for quantification of 14 steroid hormones was developed from low volume plasma in a short time using LC-MS/MS.•We developed and validated the approach…”
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Lipidomic and proteomic analysis of exosomes from mouse cortical collecting duct cells by Dang, Viet D., Jella, Kishore Kumar, Ragheb, Ragy R. T., Denslow, Nancy D., Alli, Abdel A.

“…ABSTRACT Exosomes are endosome‐derived nanovesicles that are involved in cellular communication and signaling. Exosomes are produced by epithelial cells and…”
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Chronic exposure to glyphosate in Florida manatee by De María, Maite, Silva-Sanchez, Cecilia, Kroll, Kevin J., Walsh, Michael T., Nouri, Mohammad-Zaman, Hunter, Margaret E., Ross, Monica, Clauss, Tonya M., Denslow, Nancy D.

“…Florida manatees were found to be chronically exposed to glyphosate and AMPA present in freshwater water bodies. This exposure was greater before and during…”
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Lipid Profiles of Urinary Extracellular Vesicles Released during the Inactive and Active Phases of Aged Male Mice with Spontaneous Hypertension by Lopez, Juliana Pena, Nouri, Mohammad-Zaman, Ebrahim, Areej, Chacko, Kevin M, Schramm, Whitney C, Gholam, Mohammed F, Ozrazgat-Baslanti, Tezcan, Denslow, Nancy D, Alli, Abdel A

“…Hypertension remains a major problem, especially in the elderly, as it increases the risk for cardiovascular, coronary artery, cerebrovascular, and kidney…”
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Dapagliflozin Treatment Augments Bioactive Phosphatidylethanolamine Concentrations in Kidney Cortex Membrane Fractions of Hypertensive Diabetic db/db Mice and Alters the Density of Lipid Rafts in Mouse Proximal Tubule Cells by Gholam, Mohammed F, Liu, Lauren P, Searcy, Louis A, Denslow, Nancy D, Alli, Abdel A

“…In addition to inhibiting renal glucose reabsorption and allowing for glucose excretion, the sodium/glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin may…”
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Mussels drive polychlorinated biphenyl (PCB) biomagnification in a coastal food web by Prince, Kimberly D., Crotty, Sinead M., Cetta, Alexa, Delfino, Joseph J., Palmer, Todd M., Denslow, Nancy D., Angelini, Christine

“…Despite international regulation, polychlorinated biphenyls (PCBs) are routinely detected at levels threatening human and environmental health. While previous…”
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Investigating an increase in Florida manatee mortalities using a proteomic approach by Lazensky, Rebecca, Silva-Sanchez, Cecilia, Kroll, Kevin J., Chow, Marjorie, Chen, Sixue, Tripp, Katie, Walsh, Michael T., Denslow, Nancy D.

“…Two large-scale Florida manatee ( Trichechus manatus latirostris ) mortality episodes were reported on separate coasts of Florida in 2013. The east coast…”
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Exploring Androgen-Regulated Pathways in Teleost Fish Using Transcriptomics and Proteomics by Martyniuk, Christopher J, Denslow, Nancy D

“…In the environment, there are aquatic pollutants that disrupt androgen signaling in fish. Laboratory and field-based experiments have utilized omics…”
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C Type Natriuretic Peptide Receptor Activation Inhibits Sodium Channel Activity in Human Aortic Endothelial Cells by Activating the Diacylglycerol-Protein Kinase C Pathway by Yu, Ling, Nouri, Mohammad-Zaman, Liu, Lauren P, Bala, Niharika, Denslow, Nancy D, LaDisa, Jr, John F, Alli, Abdel A

“…The C-type natriuretic peptide receptor (NPRC) is expressed in many cell types and binds all natriuretic peptides with high affinity. Ligand binding results in…”
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Neuroendocrine disruption of organizational and activational hormone programming in poikilothermic vertebrates by Rosenfeld, Cheryl S., Denslow, Nancy D., Orlando, Edward F., Gutierrez-Villagomez, Juan Manuel, Trudeau, Vance L

“…In vertebrates, sexual differentiation of the reproductive system and brain is tightly orchestrated by organizational and activational effects of endogenous…”
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Investigating the gene expression profiles of rehabilitated Florida manatees (Trichechus manatus latirostris) following red tide exposure by Lazensky, Rebecca, Hunter, Margaret E, Moraga Amador, David, Al-Khedery, Basima, Yu, Fahong, Walsh, Cathy, Gitzendanner, Matthew A, Tripp, Katie, Walsh, Michael T, Denslow, Nancy D

“…To investigate a Florida manatee (Trichechus manatus latirostris) mortality event following a red tide bloom in Southwest Florida, an RNA sequencing experiment…”
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Novel effective mosquito larvicide DL-methionine: Lack of toxicity to non-target aquatic organisms by Weeks, Emma N.I., Kroll, Kevin J., Johnson, Timothy S., Colquhoun, Thomas, Cuda, James P., Denslow, Nancy D., Stevens, Bruce R.

“…Mosquito larvicides are an effective tool for reducing numbers of adult females that bite and potentially spread pathogenic organisms. Methionine, an essential…”
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Human Alpha-1 Antitrypsin Attenuates ENaC and MARCKS and Lowers Blood Pressure in Hypertensive Diabetic db/db Mice by Lugo, Carlos I, Liu, Lauren P, Bala, Niharika, Morales, Angelica G, Gholam, Mohammed F, Abchee, Julia C, Elmoujahid, Nasseem, Elshikha, Ahmed Samir, Avdiaj, Rigena, Searcy, Louis A, Denslow, Nancy D, Song, Sihong, Alli, Abdel A

“…Hypertension may develop before or after the onset of diabetes and it is known to increase the risk of developing diabetic nephropathy. Alpha-1 antitrypsin…”
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Tempol Alters Urinary Extracellular Vesicle Lipid Content and Release While Reducing Blood Pressure during the Development of Salt-Sensitive Hypertension by Chacko, Kevin M, Nouri, Mohammad-Zaman, Schramm, Whitney C, Malik, Zeeshan, Liu, Lauren P, Denslow, Nancy D, Alli, Abdel A

“…Salt-sensitive hypertension resulting from an increase in blood pressure after high dietary salt intake is associated with an increase in the production of…”
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Gene expression networks underlying ovarian development in wild largemouth bass (Micropterus salmoides) by Martyniuk, Christopher J, Prucha, Melinda S, Doperalski, Nicholas J, Antczak, Philipp, Kroll, Kevin J, Falciani, Francesco, Barber, David S, Denslow, Nancy D

“…Oocyte maturation in fish involves numerous cell signaling cascades that are activated or inhibited during specific stages of oocyte development. The…”
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