Search Results - "Denooz, Raphaël"

Validation of an UHPLC/DAD method for the determination of cannabinoids in seized materials: Analysis of 213 samples sold in Belgian CBD shops by Deville, Marine, Dubois, Nathalie, Denooz, Raphaël, Charlier, Corinne

“…•A method was successfully validated for the determination of major cannabinoids in plant material.•It was then applied to 213 samples seized in CBD…”
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Temporal Stability Evaluation of Drugs in Plasma on Primary Sampling Tube by Mistretta, Virginie, Denooz, Raphaël, Charlier, Corinne

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Simultaneous determination of five β-lactam antibiotics (cefepim, ceftazidim, cefuroxim, meropenem and piperacillin) in human plasma by high-performance liquid chromatography with ultraviolet detection by Denooz, Raphaël, Charlier, Corinne

“…Monitoring of plasma antibiotic drugs is useful for better clinical management in infected patients, particularly in intensive care units. A simple and…”
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Modelled target attainment after meropenem infusion in patients with severe nosocomial pneumonia: the PROMESSE study by Frippiat, Frédéric, Musuamba, Flora Tshinanu, Seidel, Laurence, Albert, Adelin, Denooz, Raphaël, Charlier, Corinne, Van Bambeke, Françoise, Wallemacq, Pierre, Descy, Julie, Lambermont, Bernard, Layios, Nathalie, Damas, Pierre, Moutschen, Michel

“…The objective of this study was to propose an optimal treatment regimen of meropenem in critically ill patients with severe nosocomial pneumonia. Among 55…”
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SIMULTANEOUS QUANTIFICATION OF FIVE β-LACTAM ANTIBIOTICS IN HUMAN PLASMA BY HPLC-DAD: CLINICAL APPLICATION FOR CEFTAZIDIME TREATMENT IN INTENSIVE CARE UNITS by Denooz, R., Frippiat, F., Charlier, C.

“…A high-performance liquid chromatography method for the simultaneous determination of five β-lactam antibiotics (cefepime, ceftazidime, cefuroxime, meropenem…”
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Pharmacokinetic Variability and Target Attainment of Fluconazole in Critically Ill Patients by Van Daele, Ruth, Wauters, Joost, Lagrou, Katrien, Denooz, Raphaël, Hayette, Marie-Pierre, Gijsen, Matthias, Brüggemann, Roger J., Debaveye, Yves, Spriet, Isabel

“…Background: Fluconazole is one of the oldest antifungal drugs. Previous studies have raised concerns considering variability in exposure and inadequate target…”
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Fatal intoxications by acenocoumarol, phenprocoumon and warfarin: Method validation in blood using the total error approach by Denooz, Raphaël, Douamba, Zoénabo, Charlier, Corinne

“…A simple high-performance liquid chromatography (HPLC) method with ultraviolet (UV) detection has been developed and validated for simultaneous identification…”
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Proficiency Testing for Meropenem and Piperacillin Therapeutic Drug Monitoring: Preliminary Results From the Belgian Society on Infectiology and Clinical Microbiology Pharmacokinetic-Pharmacodynamic Working Group by Carlier, Mieke, Athanasopoulos, Alexandre, Borrey, Daniëlle, Colin, Pieter, Cotton, Frédéric, Denooz, Raphael, Neels, Hugo, Spriet, Isabel, Ghys, Timothy, Verstraete, Alain G, Stove, Veronique

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Modelled Target Attainment after Temocillin Treatment in Severe Pneumonia: Systemic and Epithelial Lining Fluid Pharmacokinetics of Continuous versus Intermittent Infusions by Layios, N, Visée, C, Mistretta, V, Denooz, R, Maes, N, Descy, J, Frippiat, F, Marchand, S, Grégoire, N

“…The objective of this article is to describe the population pharmacokinetics (PK) of temocillin administered via continuous infusion (CI) versus intermittent…”
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Continuous infusion of cefepime and neurotoxicity: a retrospective cohort study by Vercheval, C., Sadzot, B., Maes, N., Denooz, R., Damas, P., Frippiat, F.

“…Neurotoxicity related to cefepime is increasingly reported in the literature but specific data concerning continuous infusion (CI) of the drug are still…”
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Mechanisms of Interaction of Endocrine-Disrupting Chemicals with Glutamate-Evoked Secretion of Gonadotropin-Releasing Hormone by Rasier, Grégory, Parent, Anne-Simone, Gérard, Arlette, Denooz, Raphaël, Lebrethon, Marie-Christine, Charlier, Corinne, Bourguignon, Jean-Pierre

“…In previous studies, we detected a dichlorodiphenyltrichloroethane (DDT) derivative in the serum of children with sexual precocity after migration from…”
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Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Bupropion and its Main Metabolites in Human Whole Blood by Denooz, Raphaël, Mercerolle, Magali, Lachâtre, Gérard, Charlier, Corinne

“…A selective and sensitive ultra-performance liquid chromatography (UPLC)-electrospray ionization-tandem mass spectrometry (MS) method for simultaneous…”
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Skin protection creams in medical settings: successful or evil? by Xhauflaire-Uhoda, Emmanuelle, Macarenko, Elena, Denooz, Raphaël, Charlier, Corinne, Piérard, Gérald E

“…Chronic exposure to mild irritants including cleansing and antiseptic products used for hand hygiene generates insults to the skin. To avoid unpleasant…”
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A Fatal Case of Bupropion (Zyban®) Overdose by Mercerolle, Magali, Denooz, Raphaël, Lachâtre, Gérard, Charlier, Corinne

“…A sensitive and reproducible method for the identification and the quantitative determination of bupropion (BUP) and its major metabolites, hydroxybupropion…”
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Popliteal Vein Blood Sampling and the Postmortem Redistribution of Diazepam, Methadone, and Morphine by Lemaire, Eric, Schmidt, Carl, Denooz, Raphael, Charlier, Corinne, Boxho, Philippe

“…Postmortem redistribution (PMR) refers to the site‐ and time‐related blood drug concentration variations after death. We compared central blood (cardiac and…”
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Site‐, Technique‐, and Time‐Related Aspects of the Postmortem Redistribution of Diazepam, Methadone, Morphine, and their Metabolites: Interest of Popliteal Vein Blood Sampling by Lemaire, Eric, Schmidt, Carl, Dubois, Nathalie, Denooz, Raphael, Charlier, Corinne, Boxho, Philippe

“…Sampling site, technique, and time influence postmortem drug concentrations. In 57 cases, we studied drug concentration differences as follows: subclavian…”
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Postmortem Concentration and Redistribution of Diazepam, Methadone, and Morphine with Subclavian and Femoral Vein Dissection/Clamping by Lemaire, Eric, Schmidt, Carl, Denooz, Raphael, Charlier, Corinne, Boxho, Philippe

“…Postmortem redistribution (PMR) concerns blood drug concentration variations after death, depending on many factors such as sampling site and technique. In our…”
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Identification and Structural Elucidation of Four Cannabimimetic Compounds (RCS-4, AM-2201, JWH-203 and JWH-210) in Seized Products by Denooz, Raphael, Vanheugen, Jean-Claude, Frederich, Michel, de Tullio, Pascal, Charlier, Corinne

“…Since 2008, herbal mixtures with synthetic cannabinoid compounds have been sold as incense throughout the world. Although these new drugs are labeled as not…”
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Combined pharmacokinetic and urodynamic study of the effects of oral administration of phenylpropanolamine in female Beagle dogs by Noël, Stéphanie, Cambier, Carole, Baert, Kris, Gustin, Pascal, Denooz, Raphael, Massart, Laurent, Hamaide, Annick

“…This study investigated the differences in pharmacokinetic, urodynamic and haemodynamic parameters after administration of two dosages of phenylpropanolamine…”
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Quantification in Postmortem Blood and Identification in Urine of Tramadol and Its Two Main Metabolites in Two Cases of Lethal Tramadol Intoxication by De Backer, B., Renardy, F., Denooz, R., Charlier, C.

“…Tramadol is an opioid analgesic considered to induce fewer side effects than other compounds of this class. It has been extensively prescribed for two decades…”
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