Search Results - "Denomme, G A"

High-throughput multiplex single-nucleotide polymorphism analysis for red cell and platelet antigen genotypes by Denomme, G.A., Van Oene, M.

“…BACKGROUND: Transfusion recipients who become alloimmunized to red cell or platelet (PLT) antigens require antigen‐negative blood to limit adverse transfusion…”
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Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4 by KELTON, J. G, SMITH, J. W, WARKENTIN, T. E, HAYWARD, C. P. M, DENOMME, G. A, HORSEWOOD, P

“…Heparin-induced thrombocytopenia (HIT) is an important complication of heparin therapy. Although there is general agreement that platelet activation in vitro…”
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Maternal ABO-mismatched blood for intrauterine transfusion of severe hemolytic disease of the newborn due to anti-Rh17 by Denomme, G.A., Ryan, G., Seaward, P.G.R., Kelly, E.N., Fernandes, B.J.

“…BACKGROUND:  Clinically significant antibodies to high‐incident antigens present a challenge in hemolytic disease of the newborn. Antigen‐negative blood may be…”
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Unusual serological findings associated with ceftriaxone-induced immune hemolytic anemia in a child with disseminated low-grade glioma by Pecker, L. H., Timsar, A., Pary, P. P., Denomme, G. A., Criss, V. R., Luban, N. L. C., Hwang, E. I., Wong, E. C. C.

“…Ceftriaxone‐induced immune hemolytic anemia (CIHA) is the second most common cause of drug‐induced hemolytic anemia. Prompt recognition of this drug reaction…”
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A diagnostic test for heparin-induced thrombocytopenia: detection of platelet microparticles using flow cytometry by Lee, D H, Warkentin, T E, Denomme, G A, Hayward, C P, Kelton, J G

“…Based on our previous observation that heparin-induced thrombocytopenia (HIT) sera can generate platelet microparticles from washed platelets in a…”
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ABO sequence analysis in a family with weak expression of blood group B by Yazer, M.H., Blajchman, M.A., DiTomasso, J., Denomme, G.A.

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Maternal immunization to Gov system alloantigens on human platelets by Bordin, José O., Kelton, John G., Warner, Margaret N., Smith, James W., Denomme, Gregory A., Warkentin, Theodore E., McGrath, Katherine, Minchinton, Robyn, Hayward, Catherine P.M.

“…BACKGROUND: Immunization to platelet alloantigens can occur during pregnancy or after the transfusion of blood components. Platelet alloantibodies can cause…”
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An adenine trimer precedes a C/G polymorphism in the 3'-amplimer region of the human platelet glycoprotein IIIa intron 6 CT repeat by Denomme, G A

“…Restriction enzyme and short tandem repeat polymorphisms are often used to link a particular allele with an inheritable disease-related gene in the absence of…”
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Factor V Leiden and thrombotic complications in heparin-induced thrombocytopenia by Lee, D H, Warkentin, T E, Denomme, G A, Lagrotteria, D D, Kelton, J G

“…To determine whether factor V Leiden is associated with thrombotic events in patients with heparin-induced thrombocytopenia (HIT), we evaluated 165 patients…”
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RhD status of a fetus at risk for haemolytic disease with a discrepant maternal DNA-based RhD genotype by Denomme, Gregory A., Akoury, Hani, Sermer, Mathew, Kelton, John G.

“…The cloning of the RHD gene has made it possible to determine the RhD status of fetuses at risk for haemolytic disease due to RhD iso‐immunization using…”
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Consortium for Blood Group Genes (CBGG): 2009 report by Denomme, G A, Westhoff, C M, Castilho, L M, St-Louis, M, Castro, V, Reid, M E

“…Consortium for Blood Group Genes is a worldwide organization whose goal is to have a vehicle to interact, establish guidelines, operate a proficiency program,…”
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Characterization and localization of the Gova/b alloantigens to the glycosylphosphatidylinositol-anchored protein CDw109 on human platelets by SMITH, J. W, HAYWARD, C. P. M, HORSEWOOD, P, WARKENTIN, T. E, DENOMME, G. A, KELTON, J. C

“…The Gova/b alloantigens are expressed on a 175-kD protein (GP175) on human platelets. Anti-Gov alloantibodies have been implicated in posttransfusion purpura…”
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Consortium for Blood Group Genes (CBGG): 2008 report by Denomme, G A, Westhoff, C M, Castilho, L, Reid, M E

“…The Consortium for Blood Group Genes is a worldwide organization whose goal is to have a vehicle to interact, establish guidelines, operate a proficiency…”
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The prenatal identification of fetal compatibility in neonatal alloimmune thrombocytopenia using amniotic fluid and variable number of tandem repeat (VNTR) analysis by Denomme, G A, Waye, J S, Burrows, R F, Hayward, C P, Warkentin, T E, Horsewood, P, Smith, J W, Jelsema, R D, Zuidema, L J, Kelton, J G

“…Most severe episodes of neonatal alloimmune thrombocytopenic purpura (NATP) are caused by antiplatelet alloantibodies against the HPA-1a (PlA1) antigen…”
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A human monoclonal autoantibody to platelet glycoprotein IIb derived from normal human lymphocytes by DENOMME, G. A, SMITH, J. W, KELTON, J. G, BELL, D. A

“…Tonsillar lymphocytes from an otherwise healthy nonthrombocytopenic male child were fused with the lymphoblastoid cell line GM 4672. Twenty of 472 (4%)…”
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Activation of platelets by sera containing IgG1 heparin-dependent antibodies : An explanation for the predominance of the FcγRIIa low responder (his131) gene in patients with heparin-induced thrombocytopenia by DENOMME, G. A, WARKENTIN, T. E, HORSEWOOD, P, SHEPPARD, J.-A. I, WARNER, M. N, KELTON, J. G

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The production of human monoclonal antiplatelet auto-antibodies derived from human lymphocytes of normal origin: reactivity to DNA, anionic phospholipids and platelet proteins by Denomme, G A, Kelton, J G, Bell, D A

“…Human hybridoma monoclonal antiplatelet antibodies were produced using tonsillar lymphocytes from a nonthrombocytopenic male fused to the lymphoblastoid cell…”
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Immunoglobulin V region sequences of two human antiplatelet monoclonal autoantibodies derived from B cells of normal origin by Denomme, G A, Mahmoudi, M, Cairns, E, Bell, D A

“…Autoimmune thrombocytopenia has been attributed to the presence of antiplatelet autoantibodies which mediate platelet destruction. The derivation of these…”
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The development of a bacteriophage expression vector for cloning immunoglobulin variable region genes from B-cell genomic DNA by Denomme, G A, Song, Z, Kelton, J G

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Recommendation for validation and quality assurance of non‐invasive prenatal testing for foetal blood groups and implications for IVD risk classification according to EU regulations by Clausen, Frederik Banch, Hellberg, Åsa, Bein, Gregor, Bugert, Peter, Schwartz, Dieter, Drnovsek, Tadeja Dovc, Finning, Kirstin, Guz, Katarzyna, Haimila, Katri, Henny, Christine, O'Brien, Helen, Orzinska, Agnieszka, Sørensen, Kirsten, Thorlacius, Steinunn, Wikman, Agneta, Denomme, Gregory Andrew, Flegel, Willy Albert, Gassner, Christoph, Haas, Masja, Hyland, Catherine, Ji, Yanli, Lane, William J., Nogués, Núria, Olsson, Martin L., Peyrard, Thierry, Schoot, C. Ellen, Weinstock, Christof, Legler, Tobias

“…Background and Objectives Non‐invasive assays for predicting foetal blood group status in pregnancy serve as valuable clinical tools in the management of…”
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