Search Results - "Denolly, Solène"

The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles by Boson, Bertrand, Legros, Vincent, Zhou, Bingjie, Siret, Eglantine, Mathieu, Cyrille, Cosset, François-Loïc, Lavillette, Dimitri, Denolly, Solène

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a β-coronavirus, is the causative agent of the COVID-19 pandemic. Like for other…”
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Lipoprotein receptors: A little grease for enveloped viruses to open the lock? by Cosset, François-Loïc, Denolly, Solène

“…Several studies recently highlighted the role of lipoprotein receptors in viral entry. These receptors are evolutionarily ancient proteins, key for the…”
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High prevalence of SARS-CoV-2 antibodies in pets from COVID-19+ households by Fritz, Matthieu, Rosolen, Béatrice, Krafft, Emilie, Becquart, Pierre, Elguero, Eric, Vratskikh, Oxana, Denolly, Solène, Boson, Bertrand, Vanhomwegen, Jessica, Gouilh, Meriadeg Ar, Kodjo, Angeli, Chirouze, Catherine, Rosolen, Serge G., Legros, Vincent, Leroy, Eric M.

“…In a survey of household cats and dogs of laboratory-confirmed COVID-19 patients, we found a high seroprevalence of SARS-CoV-2 antibodies, ranging from 21% to…”
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The interplays between Crimean-Congo hemorrhagic fever virus (CCHFV) M segment-encoded accessory proteins and structural proteins promote virus assembly and infectivity by Freitas, Natalia, Enguehard, Margot, Denolly, Solène, Levy, Camille, Neveu, Gregory, Lerolle, Solène, Devignot, Stephanie, Weber, Friedemann, Bergeron, Eric, Legros, Vincent, Cosset, François-Loïc

“…Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne orthonairovirus that has become a serious threat to the public health. CCHFV has a…”
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Overview of HCV Life Cycle with a Special Focus on Current and Possible Future Antiviral Targets by Alazard-Dany, Nathalie, Denolly, Solène, Boson, Bertrand, Cosset, François-Loïc

“…Hepatitis C infection is the leading cause of liver diseases worldwide and a major health concern that affects an estimated 3% of the global population. Novel…”
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Zika virus remodelled ER membranes contain proviral factors involved in redox and methylation pathways by Denolly, Solène, Stukalov, Alexey, Barayeu, Uladzimir, Rosinski, Alina N., Kritsiligkou, Paraskevi, Joecks, Sebastian, Dick, Tobias P., Pichlmair, Andreas, Bartenschlager, Ralf

“…Zika virus (ZIKV) has emerged as a global health issue, yet neither antiviral therapy nor a vaccine are available. ZIKV is an enveloped RNA virus, replicating…”
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HIV fusion: Catch me if you can by Denolly, Solène, Cosset, François-Loïc

“…The penetration of enveloped viruses into target cells requires the fusion of the lipid envelope of their virions with the host lipid membrane though a…”
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Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly by Goellner, Sarah, Enkavi, Giray, Prasad, Vibhu, Denolly, Solène, Eu, Sungmin, Mizzon, Giulia, Witte, Leander, Kulig, Waldemar, Uckeley, Zina M., Lavacca, Teresa M., Haselmann, Uta, Lozach, Pierre-Yves, Brügger, Britta, Vattulainen, Ilpo, Bartenschlager, Ralf

“…For successful infection of host cells and virion production, enveloped viruses, including Zika virus (ZIKV), extensively rely on cellular lipids. However, how…”
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Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation by Kiemel, Dominik, Kroell, Ann-Sophie Helene, Denolly, Solène, Haselmann, Uta, Bonfanti, Jean-François, Andres, Jose Ignacio, Ghosh, Brahma, Geluykens, Peggy, Kaptein, Suzanne J. F., Wilken, Lucas, Scaturro, Pietro, Neyts, Johan, Van Loock, Marnix, Goethals, Olivia, Bartenschlager, Ralf

“…Dengue fever represents a significant medical and socio-economic burden in (sub)tropical regions, yet antivirals for treatment or prophylaxis are lacking…”
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The low-density lipoprotein receptor and apolipoprotein E associated with CCHFV particles mediate CCHFV entry into cells by Ritter, Maureen, Canus, Lola, Gautam, Anupriya, Vallet, Thomas, Zhong, Li, Lalande, Alexandre, Boson, Bertrand, Gandhi, Apoorv, Bodoirat, Sergueï, Burlaud-Gaillard, Julien, Freitas, Natalia, Roingeard, Philippe, Barr, John N., Lotteau, Vincent, Legros, Vincent, Mathieu, Cyrille, Cosset, François-Loïc, Denolly, Solène

“…The Crimean-Congo hemorrhagic fever virus (CCHFV) is an emerging pathogen of the Orthonairovirus genus that can cause severe and often lethal hemorrhagic…”
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Nup98 Is Subverted from Annulate Lamellae by Hepatitis C Virus Core Protein to Foster Viral Assembly by Boson, Bertrand, Mialon, Chloé, Schichl, Konstanze, Denolly, Solène, Cosset, François-Loïc

“…Nup98, an essential component of the nuclear pore that also participates in annulate lamella pore structures localized in the cytosol, is involved in hepatitis…”
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A serum protein factor mediates maturation and apoB-association of HCV particles in the extracellular milieu by Denolly, Solène, Granier, Christelle, Fontaine, Nelly, Pozzetto, Bruno, Bourlet, Thomas, Guérin, Maryse, Cosset, François-Loïc

“…[Display omitted] •After cell egress, HCV particles may associate with apoB and acquire neutral lipids, and hence, low-buoyant density.•The hypervariable…”
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Low-density hepatitis C virus infectious particles are protected from oxidation by secreted cellular proteins by Granier, Christelle, Toesca, Johan, Mialon, Chloé, Ritter, Maureen, Freitas, Natalia, Boson, Bertrand, Pécheur, Eve-Isabelle, Cosset, François-Loïc, Denolly, Solène

“…Assessments of viral stability on surfaces or in body fluids under different environmental conditions and/or temperatures are often performed, as they are key…”
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Daclatasvir Prevents Hepatitis C Virus Infectivity by Blocking Transfer of the Viral Genome to Assembly Sites by Boson, Bertrand, Denolly, Solène, Turlure, Fanny, Chamot, Christophe, Dreux, Marlène, Cosset, François-Loïc

“…Daclatasvir is a direct-acting antiviral agent and potent inhibitor of NS5A, which is involved in replication of the hepatitis C virus (HCV) genome, presumably…”
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HCV Interplay with Lipoproteins: Inside or Outside the Cells? by Cosset, François-Loïc, Mialon, Chloé, Boson, Bertrand, Granier, Christelle, Denolly, Solène

“…Hepatitis C virus (HCV) infection is a major public health issue leading to chronic liver diseases. HCV particles are unique owing to their particular lipid…”
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Membrane Fusion Assays for Studying Entry Hepatitis C Virus into Cells by Denolly, Solène, Cosset, François-Loïc, Freitas, Natalia

“…The membrane fusion properties of HCV envelope glycoproteins can be evaluated using several assays. Fusion assays generally require contacts between…”
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Unlike for cellular mRNAs and other viral internal ribosome entry sites (IRESs), the eIF3 subunit e is not required for the translational activity of the HCV IRES by Panthu, Baptiste, Denolly, Solène, Faivre-Moskalenko, Cendrine, Ohlmann, Théophile, Cosset, François-Loïc, Jalinot, Pierre

“…Viruses depend on the host cell translation machinery for their replication, and one common strategy is the presence of internal ribosome entry sites (IRESs)…”
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Report of One-Year Prospective Surveillance of SARS-CoV-2 in Dogs and Cats in France with Various Exposure Risks: Confirmation of a Low Prevalence of Shedding, Detection and Complete Sequencing of an Alpha Variant in a Cat by Krafft, Emilie, Denolly, Solène, Boson, Bertrand, Angelloz-Pessey, Sophie, Levaltier, Sophie, Nesi, Nicolas, Corbet, Sandrine, Leterrier, Bryce, Fritz, Matthieu, Leroy, Eric M., Gouilh, Meriadeg Ar, Cosset, François-Loïc, Kodjo, Angeli, Legros, Vincent

“…Despite the probable zoonotic origin of SARS-CoV-2, only limited research efforts have been made to understand the role of companion animals in SARS-CoV-2…”
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The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types by Denolly, Solène, Mialon, Chloé, Bourlet, Thomas, Amirache, Fouzia, Penin, François, Lindenbach, Brett, Boson, Bertrand, Cosset, François-Loïc

“…Viroporins are small transmembrane proteins with ion channel activities modulating properties of intracellular membranes that have diverse proviral functions…”
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Dengue virus NS1 secretion is regulated via importin-subunit β1 controlling expression of the chaperone GRp78 and targeted by the clinical drug ivermectin by Denolly, Solène, Guo, Hongbo, Martens, Miriam, Płaszczyca, Anna, Scaturro, Pietro, Prasad, Vibhu, Kongmanas, Kessiri, Punyadee, Nuntaya, Songjaeng, Adisak, Mairiang, Dumrong, Pichlmair, Andreas, Avirutnan, Panisadee, Bartenschlager, Ralf

“…Dengue virus (DENV) is a major human pathogen that can cause hemorrhagic fever and shock syndrome. One important factor of DENV pathogenicity is non-structural…”
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