Search Results - "Dennis, Vida A. "
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Pseudomonas aeruginosa reference strains PAO1 and PA14: A genomic, phenotypic, and therapeutic review
Published in Frontiers in microbiology (13-10-2022)“…is a ubiquitous, motile, gram-negative bacterium that has been recently identified as a multi-drug resistant pathogen in critical need of novel therapeutics…”
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Advances in Skin Regeneration Using Tissue Engineering
Published in International journal of molecular sciences (07-04-2017)“…Tissue engineered skin substitutes for wound healing have evolved tremendously over the last couple of years. New advances have been made toward developing…”
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Functionalized Gold Nanoparticles and Their Biomedical Applications
Published in Nanomaterials (14-06-2011)“…Metal nanoparticles are being extensively used in various biomedical applications due to their small size to volume ratio and extensive thermal stability. Gold…”
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SOCS Proteins as Regulators of Inflammatory Responses Induced by Bacterial Infections: A Review
Published in Frontiers in microbiology (12-12-2017)“…Severe bacterial infections can lead to both acute and chronic inflammatory conditions. Innate immunity is the first defense mechanism employed against…”
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Immunological challenges associated with artificial skin grafts: available solutions and stem cells in future design of synthetic skin
Published in Journal of biological engineering (13-12-2017)“…The repair or replacement of damaged skins is still an important, challenging public health problem. Immune acceptance and long-term survival of skin grafts…”
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Bystander activation of microglia by Brucella abortus -infected astrocytes induces neuronal death via IL-6 trans-signaling
Published in Frontiers in immunology (23-01-2024)“…Inflammation plays a key role in the pathogenesis of neurobrucellosis where glial cell interactions are at the root of this pathological condition. In this…”
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Suppressors of Cytokine Signaling (SOCS)1 and SOCS3 Proteins Are Mediators of Interleukin-10 Modulation of Inflammatory Responses Induced by Chlamydia muridarum and Its Major Outer Membrane Protein (MOMP) in Mouse J774 Macrophages
Published in Mediators of inflammation (2020)“…The immunopathology of chlamydial diseases is exacerbated by a broad-spectrum of inflammatory mediators, which we reported are inhibited by IL-10 in…”
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Gold nanorods inhibit respiratory syncytial virus by stimulating the innate immune response
Published in Nanomedicine (01-11-2016)“…Abstract Respiratory syncytial virus (RSV) causes severe pneumonia and bronchiolitis in infants, children and older adults. The use of metallic nanoparticles…”
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Brucella abortus‐activated microglia induce neuronal death through primary phagocytosis
Published in Glia (01-07-2017)“…Inflammation has long been implicated as a contributor to pathogenesis in neurobrucellosis. Many of the associated neurocognitive symptoms of neurobrucellosis…”
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Nanofiller-Enhanced Soft Non-Gelatin Alginate Capsules for Modified Drug Delivery
Published in Pharmaceuticals (Basel, Switzerland) (13-04-2021)“…Capsules are one of the major solid dosage forms available in a variety of compositions and shapes. Developments in this dosage form are not new, but the…”
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Encapsulation of Recombinant MOMP in Extended-Releasing PLGA 85:15 Nanoparticles Confer Protective Immunity Against a Chlamydia muridarum Genital Challenge and Re-Challenge
Published in Frontiers in immunology (14-04-2021)“…Recently we reported the immune-potentiating capacity of a nanovaccine (PLGA-rMOMP) comprising rMOMP (recombinant major outer membrane protein) encapsulated in…”
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Antibiotic Minocycline Prevents Respiratory Syncytial Virus Infection
Published in Viruses (11-08-2019)“…Treatment drugs, besides their specific activity, often have multiple effects on the body. The undesired effect of the drug may be repurposed as therapeutics,…”
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Poly(lactic acid)–poly(ethylene glycol) nanoparticles provide sustained delivery of a Chlamydia trachomatis recombinant MOMP peptide and potentiate systemic adaptive immune responses in mice
Published in Nanomedicine (01-08-2014)“…Abstract PLA–PEG [poly(lactic acid)–poly (ethylene glycol)], a biodegradable copolymer, is underexploited for vaccine delivery although it exhibits enhanced…”
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Future of human Chlamydia vaccine: potential of self-adjuvanting biodegradable nanoparticles as safe vaccine delivery vehicles
Published in Expert review of vaccines (04-03-2018)“…There is a persisting global burden and considerable public health challenge by the plethora of ocular, genital and respiratory diseases caused by members of…”
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Flavonoid Naringenin: A Potential Immunomodulator for Chlamydia trachomatis Inflammation
Published in Mediators of Inflammation (01-01-2013)“…Chlamydia trachomatis, the agent of bacterial sexually transmitted infections, can manifest itself as either acute cervicitis, pelvic inflammatory disease, or…”
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Interleukin-10 Conjugation to Carboxylated PVP-Coated Silver Nanoparticles for Improved Stability and Therapeutic Efficacy
Published in Nanomaterials (Basel, Switzerland) (02-07-2017)“…Interleukin-10 (IL-10) is a key anti-inflammatory and immunosuppressive cytokine and therefore represents a potential therapeutic agent especially in…”
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The anti-microbial peptide TP359 attenuates inflammation in human lung cells infected with Pseudomonas aeruginosa via TLR5 and MAPK pathways
Published in PloS one (03-05-2017)“…Pseudomonas aeruginosa infection induces vigorous inflammatory mediators secreted by epithelial cells, which do not necessarily eradicate the pathogen…”
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The Chlamydia M278 Major Outer Membrane Peptide Encapsulated in the Poly(lactic acid)-Poly(ethylene glycol) Nanoparticulate Self-Adjuvanting Delivery System Protects Mice Against a Chlamydia muridarum Genital Tract Challenge by Stimulating Robust Systemic and Local Mucosal Immune Responses
Published in Frontiers in immunology (15-10-2018)“…Recently, we reported that our PPM chlamydial nanovaccine [a biodegradable co-polymeric PLA-PEG (poly(lactic acid)-poly(ethylene glycol))-encapsulated M278…”
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Interleukin-10 Alters Effector Functions of Multiple Genes Induced by Borrelia burgdorferi in Macrophages To Regulate Lyme Disease Inflammation
Published in Infection and Immunity (01-12-2011)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Brucella abortus Traverses Brain Microvascular Endothelial Cells Using Infected Monocytes as a Trojan Horse
Published in Frontiers in cellular and infection microbiology (14-06-2018)“…Neurobrucellosis is an inflammatory disease caused by the invasion of spp. to the central nervous system (CNS). The pathogenesis of the disease is not well…”
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