Search Results - "Dennis, Megan K"

BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes by Delevoye, Cédric, Heiligenstein, Xavier, Ripoll, Léa, Gilles-Marsens, Floriane, Dennis, Megan K., Linares, Ricardo A., Derman, Laura, Gokhale, Avanti, Morel, Etienne, Faundez, Victor, Marks, Michael S., Raposo, Graça

“…Recycling endosomes consist of a tubular network that emerges from vacuolar sorting endosomes and diverts cargoes toward the cell surface, the Golgi, or…”
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SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation by Le, Linh, Escobar, Iliana E, Ho, Tina, Lefkovith, Ariel J, Latteri, Emily, Haltaufderhyde, Kirk D, Dennis, Megan K, Plowright, Lynn, Sviderskaya, Elena V, Bennett, Dorothy C, Oancea, Elena, Marks, Michael S

“…encodes a putative transporter expressed primarily in pigment cells. mutations cause oculocutaneous albinism type 4 (OCA4) and polymorphisms are associated…”
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Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers by Ripoll, Léa, Heiligenstein, Xavier, Hurbain, Ilse, Domingues, Lia, Figon, Florent, Petersen, Karl J, Dennis, Megan K, Houdusse, Anne, Marks, Michael S, Raposo, Graça, Delevoye, Cédric

“…Vesicular and tubular transport intermediates regulate organellar cargo dynamics. Transport carrier release involves local and profound membrane remodeling…”
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BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers by Dennis, Megan K, Delevoye, Cédric, Acosta-Ruiz, Amanda, Hurbain, Ilse, Romao, Maryse, Hesketh, Geoffrey G, Goff, Philip S, Sviderskaya, Elena V, Bennett, Dorothy C, Luzio, J Paul, Galli, Thierry, Owen, David J, Raposo, Graça, Marks, Michael S

“…Endomembrane organelle maturation requires cargo delivery via fusion with membrane transport intermediates and recycling of fusion factors to their sites of…”
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BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery by Dennis, Megan K, Mantegazza, Adriana R, Snir, Olivia L, Tenza, Danièle, Acosta-Ruiz, Amanda, Delevoye, Cédric, Zorger, Richard, Sitaram, Anand, de Jesus-Rojas, Wilfredo, Ravichandran, Keerthana, Rux, John, Sviderskaya, Elena V, Bennett, Dorothy C, Raposo, Graça, Marks, Michael S, Setty, Subba Rao Gangi

“…Hermansky-Pudlak syndrome (HPS) is a group of disorders characterized by the malformation of lysosome-related organelles, such as pigment cell melanosomes…”
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Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis by Blasko, Eric, Haskell, Christopher A, Leung, Stewart, Gualtieri, Giovanna, Halks-Miller, Meredith, Mahmoudi, Mithra, Dennis, Megan K, Prossnitz, Eric R, Karpus, William J, Horuk, Richard

“…Abstract The beneficial effects of estrogens in multiple sclerosis are thought to be mediated exclusively by the classical nuclear estrogen receptors ERα and…”
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Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes by Sitaram, Anand, Dennis, Megan K, Chaudhuri, Rittik, De Jesus-Rojas, Wilfredo, Tenza, Danièle, Setty, Subba Rao Gangi, Wood, Christopher S, Sviderskaya, Elena V, Bennett, Dorothy C, Raposo, Graça, Bonifacino, Juan S, Marks, Michael S

“…Cell types that generate unique lysosome-related organelles (LROs), such as melanosomes in melanocytes, populate nascent LROs with cargoes that are diverted…”
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G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth by Petrie, Whitney K., Dennis, Megan K., Hu, Chelin, Dai, Donghai D., Arterburn, Jeffrey B., Smith, Harriet O., Hathaway, Helen J., Prossnitz, Eric R.

“…Endometrial carcinoma is the most common cancer of the female reproductive tract. GPER/GPR30 is a 7-transmembrane spanning G protein-coupled receptor that has…”
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Synthesis and Characterization of Iodinated Tetrahydroquinolines Targeting the G Protein-Coupled Estrogen Receptor GPR30 by Ramesh, Chinnasamy, Nayak, Tapan K, Burai, Ritwik, Dennis, Megan K, Hathaway, Helen J, Sklar, Larry A, Prossnitz, Eric R, Arterburn, Jeffrey B

“…A series of iodo-substituted tetrahydro-3H-cyclopenta[c]quinolines was synthesized as potential targeted imaging agents for the G protein-coupled estrogen…”
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Synthesis and characterization of tricarbonyl-Re/Tc(I) chelate probes targeting the G protein-coupled estrogen receptor GPER/GPR30 by Burai, Ritwik, Ramesh, Chinnasamy, Nayak, Tapan K, Dennis, Megan K, Bryant, Bj K, Prossnitz, Eric R, Arterburn, Jeffrey B

“…The discovery of the G protein-coupled estrogen receptor GPER (also GPR30) and the resulting development of selective chemical probes have revealed new aspects…”
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In vivo effects of a GPR30 antagonist by Dennis, Megan K, Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K, Alcon, Sara N, Nayak, Tapan K, Bologa, Cristian G, Leitao, Andrei, Brailoiu, Eugen, Deliu, Elena, Dun, Nae J, Sklar, Larry A, Hathaway, Helen J, Arterburn, Jeffrey B, Oprea, Tudor I, Prossnitz, Eric R

“…Estrogen is central to many physiological processes throughout the human body. We have previously shown that the G protein–coupled receptor GPR30 (also known…”
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Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity by Dennis, Megan K., Field, Angela S., Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K., Bologa, Cristian G., Oprea, Tudor I., Yamaguchi, Yuri, Hayashi, Shin-Ichi, Sklar, Larry A., Hathaway, Helen J., Arterburn, Jeffrey B., Prossnitz, Eric R.

“…► We identify a GPER antagonist G36 with increased selectivity against ERα/β. ► G36 exhibits reduced ER binding/activation compared to G15. ► G36 inhibits GPER…”
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A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers by Bowman, Shanna L, Le, Linh, Zhu, Yueyao, Harper, Dawn C, Sitaram, Anand, Theos, Alexander C, Sviderskaya, Elena V, Bennett, Dorothy C, Raposo-Benedetti, Graça, Owen, David J, Dennis, Megan K, Marks, Michael S

“…Membrane transport carriers fuse with target membranes through engagement of cognate vSNAREs and tSNAREs on each membrane. How vSNAREs are sorted into…”
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A multifunctional androgen receptor screening assay using the high‐throughput Hypercyt® flow cytometry system by Dennis, Megan K., Bowles, Harmony J.C., MacKenzie, Debra A., Burchiel, Scott W., Edwards, Bruce S., Sklar, Larry A., Prossnitz, Eric R., Thompson, Todd A.

“…The androgen receptor (AR) is a steroid hormone receptor which regulates transcription of androgen‐sensitive genes and is responsible for the development and…”
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Complete genome sequence of bacteriophage MrAaronian isolated from an Arthrobacter globiformis culture by Haines, Ian, Blakely, Jessica, Branson, Ashley, Estrada, Diana, Fernandez Robles, Rebeca, Fitzgerald, Katelyn, Jeffers, Shelby, Leung, Timyee, Munoz, Jasmine, Olivos, Ashley, Ramirez, Anayeli, Smith, Caressa, Spere, Justin, Tavarez, Idaleth, Wood, Isabella, Zavala, Ethan, Arrighi, Madison, Coronel-Galindo, Angelica, Dennis, Megan K, Goppert, Marlee, Edwards, Dustin

“…Arthrobacteriophage MrAaronian contains a 54,509 bp DNA genome with 87 predicted protein-coding genes. MrAaronian has siphovirus morphology and was collected…”
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Genome sequence of bacteriophage Djungelskog isolated from an Arthrobacter globiformis culture by Oliveros, Abigail M, McDougall, Shelby A, Snyder, Miles A, Snowden, Sara K, Richard, Joseph D, Rao, Christopher M, Ponce, Marybeth, Pitonza, Christopher J, Ozcelik, Mira, Mannina, Sofia S, Magna, Juliana R, Lopez, Andrew S, Gustafson, Linnea C, Glackin, Brynn K, Dolge, Abigail E, DeLancy, Nate D, Davis, Andrew B C, Davis, Thomas P, Blagodar, Max, Natale, Sydney N, Dennis, Megan K, Godin, Elizabeth A

“…Actinobacteriophage Djungelskog was isolated from a sample of degraded organic material in Poughkeepsie, NY, using . Its genome is 54,512 bp and encodes 86…”
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The professional identity of STEM faculty as instructors of course-based research experiences by Hanauer, David, Alvey, Richard, An, Ping, Bancroft, Christa, Butela, Kristen, Coleman, Sean, Clase, Kari L., Collins, Parks, Conant, Stephanie, Connerly, Pamela, Connors, Bernadette, Dennis, Megan K., Doyle, Erin L., Edwards, Dustin, Fillman, Christy, Findley, Ann, Frost, Victoria J., Gainey, Maria, Golebiewska, Urszula, Guild, Nancy, Gusky, Sharon B., Johnson, Allison, Johnson, Kristen, Klyczek, Karen K., Lee-Soety, Julia, Lindberg, Heather, Mastropaolo, Matthew D., Merkle, Julie A., Mitchell, Jon, Molloy, Sally, Nieto, Fernando, Nissen, Jillian, Perez Morales, Tiara, Peters, Nick T., Pfeifer, Susanne P., Pollenz, Richard, Preuss, Mary L., Rosas-Acosta, Germán, Saha, Margaret S., Sprenkle, Amy, Sunnen, C. Nicole, Tobiason, Deborah, Tolsma, Sara S., Ware, Vassie, Ahumada-Santos, Yesmi Patricia, Alvarez, Regina V., Anderson, Justin, Ayuk, Mary, Báez-Flores, María Elena, Bailey, Dondra, Baliraine, Frederick, Behr, Elizabeth, Beyer, Andrea R., Bhalla, Suparna, Bono, Lisa M., Breakwell, Donald P., Byrum, Christine, Duffy, Iain, Gleichsner, Alyssa, Harrison, Melinda, Ho, Renee, Hughes, Lee E., Kagey, Jacob D., Kohl, Kathryn, McClory, Sean, Moyer, Alison, Mussi, Maria A., Nance, Holly, Nsa, Imade Y., Page, Shallee T., Parra Unda, Jesús Ricardo, Rocheleau, Jessica, Swerdlow, Sarah, Thoemke, Kara, Valentine, Megan S., Vega, Quinn C., Ward, Catherine, Williams, Daniel C., Wisner, Ellen, Biederman, William H., Cresawn, Steven G., Graham, Mark J., Hatfull, Graham, Heller, Danielle, Jacobs-Sera, Deborah, Monti, Denise, Ramakrishna, Pushpa, Russell, Daniel, Sivanathan, Viknesh

“…The professional identity of scientists has historically been cultivated to value research over teaching, which can undermine initiatives that aim to reform…”
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An inclusive Research and Education Community (iREC) model to facilitate undergraduate science education reform by Denise L. Monti, Julia C. Gill, Tamarah L. Adair, Sandra D. Adams, Yesmi Patricia Ahumada-Santos, Isabel Amaya, Kirk Anders, Justin R. Anderson, Mauricio S. Antunes, Mary Ayuk, Frederick Baliraine, Tonya C. Bates, Andrea R. Beyer, Suparna Bhalla, Tejas Bouklas, Sharon K. Bullock, Kristen A. Butela, Christine Byrum, Steven M. Caruso, Rebecca Chong, Hui-Min Chung, Stephanie B. Conant, Brett Condon, Katie E. Crump, Tom D'Elia, Megan K. Dennis, Linda C. DeVeaux, Lautaro Diacovich, Arturo Diaz, Iain Duffy, Dustin Edwards, Patricia C. Fallest-Strobl, Ann Findley, Matthew R. Fisher, Marie P. Fogarty, Victoria Jane Frost, Maria D. Gainey, Courtney S. Galle, Bryan Gibb, Urszula Golebiewska, Hugo Gramajo, Anna S. Grinath, Jennifer Guerrero, Nancy Guild, Kathryn E. Gunn, Susan Gurney, Lee E. Hughes, Pradeepa Jayachandran, Kristen Johnson, Allison Johnson, Alison E. Kanak, Michelle L. Kanther, Rodney A. King, Kathryn Kohl, Julia Lee-Soety, Lynn O. Lewis, Heather Lindberg, Jaclyn A. Madden, Breonna J. Martin, Matthew D. Mastropaolo, Sean McClory, Evan C. Merkhofer, Julie A. Merkle, Jon Mitchell, María Alejandra Mussi, Fernando Nieto, Jillian Nissen, Imade Yolanda Nsa, Mary G. O'Donnell, R. Deborah Overath, Shallee T. Page, Andrea Panagakis, Jesús Ricardo Parra Unda, Michelle B. Pass, Tiara Perez Morales, Nick T. Peters, Ruth Plymale, Richard Pollenz, Nathan S. Reyna, Claire A. Rinehart, Jessica Rocheleau, John S. Rombold, Ombeline Rossier, Adam D. Rudner, Elizabeth E. Rueschhoff, Christopher D. Shaffer, Mary Ann V. Smith, Amy B. Sprenkle, C. Nicole Sunnen, Michael A. Thomas, Michelle M. Tigges, Deborah Tobiason, Sara Sybesma Tolsma, Julie Torruellas Garcia, Peter Uetz, Edwin Vazquez, Catherine M. Ward, Vassie C. Ware, Jacqueline M. Washington, Matthew J. Waterman

“…Over the last two decades, there have been numerous initiatives to improve undergraduate student outcomes in STEM. One model for scalable reform is the…”
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Synthesis and Characterization of Tricarbonyl-Re/Tc by Burai, Ritwik, Ramesh, Chinnasamy, Nayak, Tapan K, Dennis, Megan K, Bryant, Bj K, Prossnitz, Eric R, Arterburn, Jeffrey B

“…The discovery of the G protein-coupled estrogen receptor GPER (also GPR30) and the resulting development of selective chemical probes have revealed new aspects…”
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Models of classroom assessment for course-based research experiences by Hanauer, David I., Zhang, Tong, Graham, Mark J., Adams, Sandra D., Ahumada-Santos, Yesmi Patricia, Alvey, Richard M., Antunes, Mauricio S., Ayuk, Mary A., Elena Báez-Flores, María, Bancroft, Christa T., Bates, Tonya C., Bechman, Meghan J., Behr, Elizabeth, Beyer, Andrea R., Bortz, Rebecca L., Bowder, Dane M., Briggs, Laura A., Brown-Kennerly, Victoria, Buckholt, Michael A., Bullock, Sharon K., Butela, Kristen A., Byrum, Christine A., Caruso, Steven M., Chia, Catherine P., Chong, Rebecca A., Chung, Hui-Min, Clase, Kari L., Coleman, Sean T., Parks Collins, D., Conant, Stephanie B., Condon, Brett M., Connerly, Pamela L., Connors, Bernadette J., Cook-Easterwood, Jennifer E., Crump, Katie E., D’Elia, Tom, Dennis, Megan K., DeVeaux, Linda C., Diacovich, Lautaro, Duffy, Iain, Edgington, Nicholas P., Edwards, Dustin C., Egwuatu, Tenny O. G., Eivazova, Elvira R., Fallest-Strobl, Patricia C., Fillman, Christy L., Findley, Ann M., Fisher, Emily, Fisher, Matthew R., Fogarty, Marie P., Freise, Amanda C., Frost, Victoria J., Gainey, Maria D., Garcia Costas, Amaya M., Garza, Atenea A., Gavin, Hannah E., Ghittoni, Raffaella, Gibb, Bryan, Golebiewska, Urszula P., Grinath, Anna S., Gurney, Susan M. R., Hare, Rebekah F., Heninger, Steven G., Hinz, John M., Hughes, Lee E., Jayachandran, Pradeepa, Johnson, Kristen C., Johnson, Allison A., Kanther, Michelle, Kenna, Margaret, Kirkpatrick, Bridgette L., Klyczek, Karen K., Kohl, Kathryn P., Kuchka, Michael, LaPeruta, Amber J., Lee-Soety, Julia Y., Lewis, Lynn O., Lindberg, Heather M., Madden, Jaclyn A., Markov, Sergei A., Mastropaolo, Matthew D., Mathur, Vinayak, McClory, Sean P., Merkhofer, Evan C., Merkle, Julie A., Michael, Scott F., Mitchell, Jon C., Molloy, Sally D., Monti, Denise L., Mussi, María Alejandra, Nance, Holly, Nieto-Fernandez, Fernando E., Nissen, Jillian C., Nsa, Imade Y., O’Donnell, Mary G., Page, Shallee T., Panagakis, Andrea, Parra-Unda, Jesús Ricardo, Pelletier, Tara A., Perez Morales, Tiara G.

“…Course-based research pedagogy involves positioning students as contributors to authentic research projects as part of an engaging educational experience that…”
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