Search Results - "Dennis, EA"

Spinal glial TLR4‐mediated nociception and production of prostaglandin E2 and TNF by Saito, O, Svensson, CI, Buczynski, MW, Wegner, K, Hua, X‐Y, Codeluppi, S, Schaloske, RH, Deems, RA, Dennis, EA, Yaksh, TL

“…Background and purpose:  Toll‐like receptor 4 (TLR4) expressed on spinal microglia and astrocytes has been suggested to play an important role in the…”
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Among patients with acute seizure-like activity, what is the value of a serum prolactin level? by Ea, Dennis, Fallert, Christopher

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MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines by Burla, Bo, Arita, Makoto, Arita, Masanori, Bendt, Anne K, Cazenave-Gassiot, Amaury, Dennis, Edward A, Ekroos, Kim, Han, Xianlin, Ikeda, Kazutaka, Liebisch, Gerhard, Lin, Michelle K, Loh, Tze Ping, Meikle, Peter J, Orešič, Matej, Quehenberger, Oswald, Shevchenko, Andrej, Torta, Federico, Wakelam, Michael J O, Wheelock, Craig E, Wenk, Markus R

“…Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in hospital settings. The inventory of lipid molecules found in…”
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The expanding superfamily of phospholipase A(2) enzymes: classification and characterization by Six, D A, Dennis, E A

“…The phospholipase A(2) (PLA(2)) superfamily consists of a broad range of enzymes defined by their ability to catalyze the hydrolysis of the middle (sn-2) ester…”
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Phospholipase A(2) regulation of arachidonic acid mobilization by Balsinde, Jesús, Winstead, Michelle V, Dennis, Edward A

“…Phospholipase A(2) (PLA(2)) constitutes a growing superfamily of lipolytic enzymes, and to date, at least 19 distinct enzymes have been found in mammals. This…”
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Combined inhibition of JAK/STAT and BCL2 during ex vivo NK cell expansion enriches a highly cytotoxic NK cell subset by Walker, Kirsti Lorraine, Gavcovich, Tara B, Ea, Dennis, Capitini, Christian M.

“…Abstract Ex vivo expansion of human NK cells with CD137L and IL-15 is being explored both preclinically and clinically as a means of increasing the number and…”
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Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis by Christianson, Christina A., Dumlao, Darren S., Stokes, Jennifer A., Dennis, Edward A., Svensson, Camilla I., Corr, Maripat, Yaksh, Tony L.

“…Neither Tlr4 −/− K/BxN serum transfer arthritic mice nor those administered spinal TLR4 pharmacological blockade display persistent mechanical…”
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A comprehensive classification system for lipids by Fahy, Eoin, Subramaniam, Shankar, Brown, H Alex, Glass, Christopher K, Merrill, Jr, Alfred H, Murphy, Robert C, Raetz, Christian R H, Russell, David W, Seyama, Yousuke, Shaw, Walter, Shimizu, Takao, Spener, Friedrich, van Meer, Gerrit, VanNieuwenhze, Michael S, White, Stephen H, Witztum, Joseph L, Dennis, Edward A

“…Lipids are produced, transported, and recognized by the concerted actions of numerous enzymes, binding proteins, and receptors. A comprehensive analysis of…”
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Dysregulation of lipidomic profile and antiviral immunity in response to hyaluronan in patients with severe asthma by Sokolowska, Milena, MD, PhD, Chen, Li-Yuan, PhD, Liu, Yueqin, PhD, Martinez-Anton, Asuncion, PhD, Logun, Carolea, MSc, Alsaaty, Sara, MSc, Cuento, Rosemarie A., MSc, Cai, Rongman, PhD, Sun, Junfeng, PhD, Quehenberger, Oswald, PhD, Armando, Aaron M., MS, Dennis, Edward A., PhD, Levine, Stewart J., MD, Shelhamer, James H., MD

“…Hyaluronan (HA), a major component of extracellular matrix, accumulates in the lung and serum of asthmatic patients and correlates with disease severity.3…”
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Spinal glial TLR4‐mediated nociception and production of prostaglandin E 2 and TNF by Saito, O, Svensson, CI, Buczynski, MW, Wegner, K, Hua, X‐Y, Codeluppi, S, Schaloske, RH, Deems, RA, Dennis, EA, Yaksh, TL

“…Background and purpose:  Toll‐like receptor 4 (TLR4) expressed on spinal microglia and astrocytes has been suggested to play an important role in the…”
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Calcium-independent phospholipase A(2): structure and function by Winstead, M V, Balsinde, J, Dennis, E A

“…The classical Ca(2+)-independent phospholipase A(2) enzyme, now known as Group VIA PLA(2), was initially purified and characterized from the P388D(1)…”
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Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids. Importance of Schiff base formation and aldol condensation by Friedman, Peter, Horkko, Sohvi, Steinberg, Daniel, Witztum, Joseph L, Dennis, Edward A

“…The oxidation of low density lipoproteins (LDL) has been correlated with atherogenesis through a variety of pathways. The process involves nonspecific…”
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Distinct Roles in Signal Transduction for Each of the Phospholipase A Enzymes Present in P388D Macrophages by Jesús Balsinde, Edward A. Dennis

“…Receptor-stimulated arachidonic acid (AA) mobilization in P388D macrophages consists of a transient phase in which AA accumulates in the cell and a sustained…”
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Phosphocholine as a pattern recognition ligand for CD36[superscript ,] by Boullier, Agnès, Friedman, Peter, Harkewicz, Richard, Hartvigsen, Karsten, Green, Simone R, Almazan, Felicidad, Dennis, Edward A, Steinberg, Daniel, Witztum, Joseph L, Quehenberger, Oswald

“…We have previously shown that CD36 recognizes oxidation products of phospholipids on oxidized LDL (OxLDL) such as…”
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Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins by Hörkkö, S, Bird, D A, Miller, E, Itabe, H, Leitinger, N, Subbanagounder, G, Berliner, J A, Friedman, P, Dennis, E A, Curtiss, L K, Palinski, W, Witztum, J L

“…We recently cloned monoclonal IgM autoantibodies which bind to epitopes of oxidized low-density lipoprotein (OxLDL) from apoE-deficient mice (EO-…”
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Scavenger Receptors, Oxidized LDL, and Atherosclerosis by BOULLIER, AGNES, BIRD, DAVID A., CHANG, MI-KYUNG, DENNIS, EDWARD A., FRIEDMAN, PETER, GILLOTTE-TAYLOR, KRISTIN, HÖRKKÖ, SOHVI, PALINSKI, WULF, QUEHENBERGER, OSWALD, SHAW, PETER, STEINBERG, DANIEL, TERPSTRA, VALESKA, WITZTUM, JOSEPH L.

“…: Oxidized LDL (OxLDL) competes with oxidatively damaged and apoptotic cells for binding to mouse peritoneal macrophages, implying the presence of one or more…”
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Monoclonal Antibodies against Oxidized Low-Density Lipoprotein Bind to Apoptotic Cells and Inhibit Their Phagocytosis by Elicited Macrophages: Evidence That Oxidation-Specific Epitopes Mediate Macrophage Recognition by Chang, Mi-Kyung, Bergmark, Claes, Laurila, Aino, Hörkkö, Sohvi, Han, Ki-Hoon, Friedman, Peter, Dennis, Edward A., Witztum, Joseph L.

“…Apoptosis is recognized as important for normal cellular homeostasis in multicellular organisms. Although there have been great advances in our knowledge of…”
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Expression and function of phospholipase A(2) in brain by Balboa, María A, Varela-Nieto, Isabel, Killermann Lucas, Karin, Dennis, Edward A

“…Phospholipase A(2) (PLA(2)) appears to play a fundamental role in cell injury in the central nervous system. We have investigated PLA(2) expression in the…”
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The Binding of Oxidized Low Density Lipoprotein to Mouse CD36 Is Mediated in Part by Oxidized Phospholipids That Are Associated with Both the Lipid and Protein Moieties of the Lipoprotein by Boullier, Agnès, Gillotte, Kristin L., Hörkkö, Sohvi, Green, Simone R., Friedman, Peter, Dennis, Edward A., Witztum, Joseph L., Steinberg, Daniel, Quehenberger, Oswald

“…There is growing evidence that CD36 has an important physiological function in the uptake of oxidized low density lipoprotein (OxLDL) by macrophages. However,…”
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Lipid Signaling Enzymes and Surface Dilution Kinetics (∗) by Carman, George M., Deems, Raymond A., Dennis, Edward A.

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