Search Results - "Denning, Stephen M."

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    Differential expression of tissue factor protein in directional atherectomy specimens from patients with stable and unstable coronary syndromes by ANNEX, B. H, DENNING, S. M, CHANNON, K. M, SKETCH, M. H, STACK, R. S, MORRISSEY, J. H, PETERS, K. G

    Published in Circulation (New York, N.Y.) (01-02-1995)
    “…Tissue factor (TF) is a cell membrane-associated protein that catalyzes the rate-limiting step of the extrinsic coagulation pathway, which is the major source…”
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    Conference Proceeding Journal Article
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    Characterization of human thymic epithelial cell surface antigens : phenotypic similarity of thymic epithelial cells to epidermal keratinocytes by PATEL, D. D, WHICHARD, L. P, RADCLIFF, G, DENNING, S. M, HAYNES, B. F

    Published in Journal of clinical immunology (01-03-1995)
    “…Cellular interactions between developing thymocytes and cells of the thymic microenvironment are necessary for maturation of thymocytes into mature T cells…”
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    Journal Article
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    Removal of Fibroblasts from Human Epithelial Cell Cultures with Use of a Complement Fixing Monoclonal Antibody Reactive with Human Fibroblasts and Monocytes/Macrophages by Singer, Kay H., Scearce, Richard M., Tuck, Debbi T., Whichard, Leona P., Denning, Stephen M., Haynes, Barton F.

    Published in Journal of investigative dermatology (01-02-1989)
    “…A complement fixing IgM monoclonal antibody (1B10) that reacts with surface membrane molecules of human fibroblasts, tissue macrophages, and peripheral…”
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    Journal Article
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    Collagen subtypes III and IV expression in human vein graft atherosclerosis by Denning, S M, Channon, K M, Peters, K G, Oldham, Jr, H N, Annex, B H

    Published in The American journal of cardiology (15-09-1996)
    “…This study examined the expression of collagen subtypes III and IV in a series of freshly excised human venous coronary artery bypass grafts. The results of…”
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    Journal Article
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    The Role of Adhesion Molecules in Epithelial–T-Cell Interactions in Thymus and Skin by Singer, Kay H, Le, Phong T, Denning, Stephen M, Whichard, Leona P, Haynes, Barton F

    Published in Journal of investigative dermatology (01-06-1990)
    “…Interaction of T lymphocytes with other cell types is important for normal T-cell development and function. Recently, a number of adhesion molecules important…”
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    Journal Article Conference Proceeding
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    The Gene SCL is Expressed during Early Hematopoiesis and Encodes a Differentiation-Related DNA-Binding Motif by Begley, C. Glenn, Aplan, Peter D., Denning, Stephen M., Haynes, Barton F., Waldmann, Thomas A., Kirsch, Ilan R.

    “…We have identified the human gene, SCL. We discovered this gene because of its involvement in a chromosomal translocation associated with the occurrence of a…”
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    Journal Article
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    Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation by DENNING, S. M, LE, BP.T, SINGER, K. H, HAYNES, B. F

    Published in The Journal of immunology (1950) (1990)
    “…The CD44 inhibitor Lutheran [In(Lu)]-related p80 molecule has recently been shown to be identical to the Hermes-1 lymphocyte homing receptor and to the human…”
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    Journal Article
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    Thymocyte LFA-1 and thymic epithelial cell ICAM-1 molecules mediate binding of activated human thymocytes to thymic epithelial cells by Singer, KH, Denning, SM, Whichard, LP, Haynes, BF

    Published in The Journal of immunology (1950) (15-04-1990)
    “…We have investigated the binding in vitro of activated thymocytes to thymic epithelial (TE) cells, and studied the effect of up-regulation of TE cell surface…”
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    Journal Article
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    Human intrathymic T cell differentiation by Haynes, B F, Denning, S M, Le, P T, Singer, K H

    Published in Seminars in immunology (01-01-1990)
    “…The human thymus develops early on in fetal gestation with morphologic maturity reached by the beginning of the second trimester. Endodermal epithelial tissue…”
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    Journal Article
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    Immature Human Thymocytes Can be Driven to Differentiate into Nonlymphoid Lineages by Cytokines from Thymic Epithelial Cells by Kurtzberg, Joanne, Denning, Stephen M., Nycum, Lynn M., Singer, Kay H., Haynes, Barton F.

    “…The signals and cellular interactions required for hematopoietic stem-cell commitment to the T lineage are unknown, yet are central to understanding the early…”
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    Journal Article
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    CD3 δ and ϵ gene expression in CD3 t-CD16 + natural killer cell clones derived from thymic precursors by DeNofrio, David, Radcliff, Gilbert, Weinhold, Kent J., Denning, Stephen M.

    Published in Human immunology (1995)
    “…To better understand the maturational stages during T-cell development, we studied the expression of CD3δ and CD3ϵ genes, as well as the presence of TCR gene…”
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    Journal Article
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    Human Thymic Epithelial Cells Directly Induce Activation of Autologous Immature Thymocytes by Denning, Stephen M., Kurtzberg, Joanne, Le, Phong T., Tuck, Debbi T., Singer, Kay H., Haynes, Barton F.

    “…To study the role that epithelial cells of the thymic microenvironment play in promoting activation of immature CD7+, CD2+, CD4-, CD8- (double-negative) human…”
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    Journal Article
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    797-1 Differential Expression of Tissue Factor Protein in Directional Atherectomy Specimens from Patients with Stable and Unstable Coronary Syndromes by Annex, Brian H., Denning, Stephen M., Channon, Keith, Sketch, Michael H., Stack, Richard S., Peters, Kevin G.

    “…Tissue factor (TF) is a cell membrane-associated protein that catalyzes the rate-limiting step of the extrinsic coagulation pathway, which is the major source…”
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    Journal Article
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    A novel activation pathway for mature thymocytes: costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation by SOO YOUNG YANG, DENNING, S. M, MIZUNO, S, DUPONT, B, HAYNES, B. F

    Published in The Journal of experimental medicine (01-10-1988)
    “…Prior studies have shown that thymocytes, unlike peripheral T cells, do not proliferate in response to mitogenic combinations of anti-CD2 mAbs. The present…”
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    Journal Article
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    Novel mechanisms of brequinar sodium immunosuppression on T cell activation by Forrest, T L, Ware, R E, Howard, T, Jaffee, B D, Denning, S M

    Published in Transplantation (27-10-1994)
    “…Brequinar sodium (BQR) is a novel immunosuppressive agent that acts by inhibiting the activity of dihydroorotate dehydrogenase, the fourth enzyme in the de…”
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    Journal Article