Search Results - "Denning, David W"

The WHO fungal priority pathogens list as a game-changer by Fisher, Matthew C., Denning, David W.

“…Invasive fungal diseases are on the increase globally. The World Health Organization fungal priority pathogens list highlights fungi of critical or high…”
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How to bolster the antifungal pipeline by Denning, David W, Bromley, Michael J

“…Few drugs are coming to market, but opportunities for drug development exist About 1.2 billion people worldwide are estimated to suffer from a fungal disease (…”
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Pulmonary cryptococcosis: A review of pathobiology and clinical aspects by Setianingrum, Findra, Rautemaa-Richardson, Riina, Denning, David W

“…Pulmonary cryptococcosis is an important opportunistic invasive mycosis in immunocompromised patients, but it is also increasingly seen in immunocompetent…”
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Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis by Rajasingham, Radha, Dr, Smith, Rachel M, MD, Park, Benjamin J, MD, Jarvis, Joseph N, MRCP, Govender, Nelesh P, MMed, Chiller, Tom M, MD, Denning, David W, Prof, Loyse, Angela, MD [Res], Boulware, David R, MD

“…Summary Background Cryptococcus is the most common cause of meningitis in adults living with HIV in sub-Saharan Africa. Global burden estimates are crucial to…”
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The global distribution of actinomycetoma and eumycetoma by Emery, Darcy, Denning, David W

“…Background Mycetoma, a chronic infection of the skin and underlying structures, affects those with a close relationship to the land, often in resource-poor…”
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Tackling human fungal infections by Brown, Gordon D, Denning, David W, Levitz, Stuart M

“…Fungi infect billions of people every year, yet their contribution to the global burden of disease is largely unrecognized. Most are “relatively” minor…”
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Innate and Adaptive Immune Defects in Chronic Pulmonary Aspergillosis by Bongomin, Felix, Harris, Chris, Foden, Philip, Kosmidis, Chris, Denning, David W

“…We evaluated the expression of biomarkers of innate and adaptive immune response in correlation with underlying conditions in 144 patients with chronic…”
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Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision by Bongomin, Felix, Gago, Sara, Oladele, Rita O, Denning, David W

“…Fungal diseases kill more than 1.5 million and affect over a billion people. However, they are still a neglected topic by public health authorities even though…”
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Renaming Candida glabrata-A case of taxonomic purity over clinical and public health pragmatism by Denning, David W

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Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management by Denning, David W, Cadranel, Jacques, Beigelman-Aubry, Catherine, Ader, Florence, Chakrabarti, Arunaloke, Blot, Stijn, Ullmann, Andrew J, Dimopoulos, George, Lange, Christoph

“…Chronic pulmonary aspergillosis (CPA) is an uncommon and problematic pulmonary disease, complicating many other respiratory disorders, thought to affect ~240…”
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Estimation of the burden of chronic and allergic pulmonary aspergillosis in India by Agarwal, Ritesh, Denning, David W, Chakrabarti, Arunaloke

“…It would be of considerable interest to clinicians if the burden of chronic pulmonary aspergillosis (CPA) and allergic bronchopulmonary aspergillosis (ABPA) in…”
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Therapy for fungal diseases: opportunities and priorities by Denning, David W, Hope, William W

“…This article provides a perspective on the current status of drug therapy for invasive fungal diseases, together with priorities for the future development of…”
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Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America by Patterson, Thomas F, Thompson, 3rd, George R, Denning, David W, Fishman, Jay A, Hadley, Susan, Herbrecht, Raoul, Kontoyiannis, Dimitrios P, Marr, Kieren A, Morrison, Vicki A, Nguyen, M Hong, Segal, Brahm H, Steinbach, William J, Stevens, David A, Walsh, Thomas J, Wingard, John R, Young, Jo-Anne H, Bennett, John E

“…It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment…”
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Twelve-month clinical outcomes of 206 patients with chronic pulmonary aspergillosis by Bongomin, Felix, Harris, Chris, Hayes, Gemma, Kosmidis, Chris, Denning, David W

“…There is a paucity of evidence surrounding the optimal antifungal therapy for use in chronic pulmonary aspergillosis (CPA) and the duration of therapy remains…”
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Hidden killers: human fungal infections by Brown, Gordon D, Denning, David W, Gow, Neil A R, Levitz, Stuart M, Netea, Mihai G, White, Theodore C

“…Although fungal infections contribute substantially to human morbidity and mortality, the impact of these diseases on human health is not widely appreciated…”
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Multi-country estimate of different manifestations of aspergillosis in cystic fibrosis by Armstead, Joanne, Morris, Julie, Denning, David W

“…Aspergillus spp. can lead to allergic bronchopulmonary aspergillosis (ABPA), Aspergillus sensitisation and Aspergillus bronchitis in CF. The relative…”
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Comparison of six Aspergillus -specific IgG assays for the diagnosis of chronic pulmonary aspergillosis (CPA) by Page, Iain D, Richardson, Malcolm D, Denning, David W

“…Summary Objectives Chronic pulmonary aspergillosis (CPA) is estimated to affect 3 million persons worldwide. Aspergillus -specific IgG is a key component in…”
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Global burden of chronic pulmonary aspergillosis complicating sarcoidosis by DENNING, David W, PLEUVRY, Alex, COLE, Donald C

“…Chronic pulmonary aspergillosis (CPA) may complicate pulmonary sarcoidosis. We re-estimated the global burden of sarcoidosis and the burden of CPA complicating…”
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Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture by Fisher, Matthew C, Gurr, Sarah J, Cuomo, Christina A, Blehert, David S, Jin, Hailing, Stukenbrock, Eva H, Stajich, Jason E, Kahmann, Regine, Boone, Charles, Denning, David W, Gow, Neil A R, Klein, Bruce S, Kronstad, James W, Sheppard, Donald C, Taylor, John W, Wright, Gerard D, Heitman, Joseph, Casadevall, Arturo, Cowen, Leah E

“…The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with respect to its profound impact on global health, biodiversity,…”
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Predictors of mortality in chronic pulmonary aspergillosis by Lowes, David, Al-Shair, Khaled, Newton, Pippa J, Morris, Julie, Harris, Chris, Rautemaa-Richardson, Riina, Denning, David W

“…Chronic pulmonary aspergillosis (CPA) is a chronic progressive infection that destroys lung tissue in non-immunocompromised patients. Contemporary series…”
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