Search Results - "Denning, C"

Small molecule absorption by PDMS in the context of drug response bioassays by van Meer, B.J., de Vries, H., Firth, K.S.A., van Weerd, J., Tertoolen, L.G.J., Karperien, H.B.J., Jonkheijm, P., Denning, C., IJzerman, A.P., Mummery, C.L.

“…The polymer polydimethylsiloxane (PDMS) is widely used to build microfluidic devices compatible with cell culture. Whilst convenient in manufacture, PDMS has…”
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Mixed-methods process evaluation of a residence-based SARS-CoV-2 testing participation pilot on a UK university campus during the COVID-19 pandemic by Blake, H, Carlisle, S, Fothergill, L, Hassard, J, Favier, A, Corner, J, Ball, J K, Denning, C

“…Regular testing for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is an important strategy for controlling virus outbreaks on university…”
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‘Project period’: a workplace health promotion innovation in a higher education setting by Blake, H, Raniga, K, Yildirim, M, Denning, C

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Older adults’ physical activity-related social control and social support in the context of personal norms by Newsom, Jason T, Denning, Emily C, Shaw, Benjamin A, August, Kristin J, Strath, Scott J

“…This study investigated whether perceived physical activity norms moderated the effects of physical activity-related social interactions on intentions to…”
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The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout by Knight, H, Jia, R, Ayling, K, Blake, H, Morling, JR, Villalon, AM, Corner, J, Denning, C, Ball, J, Bolton, K, Figueredo, G, Morris, D, Tighe, P, Vedhara, K

“…Aims: Development and rollout of vaccines offers the best opportunity for population protection against the SARS-CoV-2 (COVID-19) virus. However, hesitancy…”
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Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes by Braam, S R, Tertoolen, L, Casini, S, Matsa, E, Lu, H R, Teisman, A, Passier, R, Denning, C, Gallacher, D J, Towart, R, Mummery, C L

“…Unexpected induction of arrhythmias in the heart is still one of the major risks of new drugs despite recent improvements in cardiac safety assays. Here we…”
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Prophylactic surgical drainage is associated with increased infection following intramedullary nailing of diaphyseal long bone fractures: A prospective cohort study in Nigeria by Oguzie, Gerald Chukwuemeka, Albright, Patrick, Ali, Syed Haider, Duru, Ndubuisi E, Iyidobi, Emmanuel Chino, Lasebikan, Omolade Ayoola, Chukwumam, Denning C, Wu, Hao-Hua, Ikpeme, Ikpeme A

“…Prophylactic surgical drains are commonly used in Nigeria following intramedullary nailing (IMN) of long bone diaphyseal fractures. However, evidence in the…”
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Deletion of the α(1,3)galactosyl transferase ( GGTA1 ) gene and the prion protein ( PrP ) gene in sheep by Clark, A. J, Denning, C, Burl, S, Ainslie, A, Bracken, J, Dinnyes, A, Fletcher, J, King, T, Ritchie, M, Ritchie, W. A, Rollo, M, de Sousa, P, Travers, A, Wilmut, I

“…Nuclear transfer offers a cell-based route for producing precise genetic modifications in a range of animal species. Using sheep, we report reproducible…”
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New frontiers in gene targeting and cloning: success, application and challenges in domestic animals and human embryonic stem cells by Denning, C, Priddle, H

“…Until recently, precise modification of the animal genome by gene targeting was restricted to the mouse because germline competent embryonic stem cells are not…”
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Human embryonic stem cells and their derivatives for environment-epigenome assessment by Young, L., Coneyworth, L., Sun, Y., Sewell, L., Bispham, J., Denning, C.

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Cardiomyocytes from human embryonic stem cells by Passier, R, Denning, C, Mummery, C

“…Terminal heart failure is characterized by a significant loss of cardiac myocytes. Stem cells represent a possibility for replacing these lost myocytes but the…”
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Where Did I Go Wrong with My Model? Ten Tips for Getting Results in SEM by Newsom, Jason T., Hachem, Zeinab A., Granger, Aeleah M., Denning, Emily C.

“…Those new to structural equation modeling (SEM) often encounter problems with convergence, software errors, or poor fitting models. Some basic suggestions are…”
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P13 Assessing viral rescue therapies for Duchenne muscular dystrophy by Ritso, M, Dick, E, Reza, M, Laval, S, Bushby, K, Straub, V, Denning, C, Lochmüller, H

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P09 Patient-specific viral rescue therapies for Duchenne muscular dystrophy by Ritso, M, Dick, E, Reza, M, Laval, S, Straub, V, Denning, C, Lochmüller, H

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Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes by Denning, C, Pitts, J D

“…Transfer of suicide genes into tumor cells renders them sensitive to cytotoxic effects of specific prodrugs. We show here that both the herpes simplex virus…”
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P4.36 Develoment of pluripotent stem celss as vectors for viral gene therapy by Ritso, M, Dick, E, Reza, M, Laval, S, Bushby, K, Straub, V, Denning, C, Lochmuller, H

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A Change for the Worse: Negative Social Exchanges are Associated with an Accelerated Decline in Self-Rated Health Over Time by Newsom, Jason T., McQueen, Ann, Rook, Karen S., Krause, Neal, Denning, Emily C.

“…Objectives Age-associated accelerated declines in physical health vary across individuals, and researchers have suggested that individual differences in…”
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Physical Activity as a Mediator Between Race/Ethnicity and Changes in Multimorbidity by Newsom, Jason T, Denning, Emily C, Elman, Miriam R, Botoseneanu, Anda, Allore, Heather G, Nagel, Corey L, Dorr, David A, Quiñones, Ana R

“…Abstract Objectives Studies report racial/ethnic disparities in multimorbidity (≥2 chronic conditions) and their rate of accumulation over time as well as…”
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Low-Pressure Helicon-Plasma Discharge Initiation via Magnetic Field Ramping by Wiebold, M., He Ren, Denning, C.M., Scharer, J.E.

“…Discharge initiation at low pressures and flow rates is investigated in the Madison helicon experiment flowing helicon source. At low pressures (below 14-sccm…”
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Ultrashort echo time (UTE) imaging reveals a shift in bound water that is sensitive to sub-clinical tendinopathy in older adults by Loegering, Isaac F., Denning, Sarah C., Johnson, Kevin M., Liu, Fang, Lee, Kenneth S., Thelen, Darryl G.

“…Objective Use ultrashort echo time (UTE) magnetic resonance imaging to quantify bound water components of asymptomatic older Achilles tendons and investigate…”
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