Search Results - "Denisova, Natalia A."

Role of membrane lipids in regulation of vulnerability to oxidative stress in PC12 cells: implication for aging by Denisova, Natalia A, Cantuti-Castelvetri, Ippolita, Hassan, Waleed N, Paulson, K.Eric, Joseph, James A

“…Previously, we reported that PC12 cells showed increased vulnerability to oxidative stress (OS) induced by H 2O 2 (as assessed by decrements in calcium…”
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Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation by Joseph, James A, Shukitt-Hale, Barbara, Denisova, Natalia A, Bielinski, Donna, Martin, Antonio, McEwen, John J, Bickford, Paula C

“…Ample research indicates that age-related neuronal-behavioral decrements are the result of oxidative stress that may be ameliorated by antioxidants. Our…”
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Copernicus revisited: amyloid beta in Alzheimer’s disease by Josepha, James, Shukitt-Hale, Barbara, Denisova, Natalia A, Martin, Antonio, Perry, George, Smith, Mark A

“…The beta-amyloid hypothesis of Alzheimer’s Disease (AD) has dominated the thinking and research in this area for over a decade and a half. While there has been…”
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Vitamin K and Sphingolipid Metabolism: Evidence to Date by Denisova, Natalia A, Booth, Sarah L

“…The brain is enriched with sphingolipids, which are important membrane constituents and major lipid signaling molecules that have a role in motor and cognitive…”
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Vitamin K and sphingolipid metabolism: Evidence to date by Denisova, N.A, Booth, S.L

“…The brain is enriched with sphingolipids, which are important membrane constituents and major lipid signaling molecules that have a role in motor and cognitive…”
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The role of glutathione, membrane sphingomyelin, and its metabolites in oxidative stress-induced calcium “dysregulation” in PC12 cells by Denisova, Natalia A, Fisher, Derek, Provost, Melanie, Joseph, James A

“…Previous research showed that increasing membrane sphingomyelin (SPH) levels in rat pheochromocytoma (PC12) cells to the same extent as that seen in some brain…”
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The nitrone spin trap PBN alters the cellular response to H2O2: activation of the EGF receptor/ERK pathway by Hassan, Waleed N, Cantuti-Castelevetri, Ippolita, Denisova, Natalia A, Yee, Amy S, Joseph, James A, Paulson, K.Eric

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The nitrone spin trap PBN alters the cellular response to H(2)O(2): activation of the EGF receptor/ERK pathway by Hassan, Waleed N, Cantuti-Castelevetri, Ippolita, Denisova, Natalia A, Yee, Amy S, Joseph, James A, Paulson, K Eric

“…The nitrone spin trap PBN has been shown to protect neuronal cells from reactive oxygen species both in culture and in vivo. As an approach to understanding…”
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The nitrone spin trap PBN alters the cellular response to H 2O 2: activation of the EGF receptor/ERK pathway by Hassan, Waleed N, Cantuti-Castelevetri, Ippolita, Denisova, Natalia A, Yee, Amy S, Joseph, James A, Paulson, K.Eric

“…The nitrone spin trap PBN has been shown to protect neuronal cells from reactive oxygen species both in culture and in vivo. As an approach to understanding…”
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Oxidant Injury in PC12 Cells—A Possible Model of Calcium “Dysregulation” in Aging: II. Interactions with Membrane Lipids by Denisova, Natalia A., Strain, Joy G., Joseph, James A.

“…: In a model recently developed to study the parameters altering vulnerability to oxidative stress, it was shown via image analysis that H2O2‐exposed PC12…”
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Differential effect of aging on cholesterol modulation of carbachol-stimulated low-K(m) GTPase in striatal synaptosomes by Denisova, N A, Erat, S A, Kelly, J F, Roth, G S

“…Previous research has suggested that age-related decline in physiological functions may be the result of substantial alterations in membrane molecular…”
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Differential Effect of Aging on Cholesterol Modulation of Carbachol-Stimulated Low- Km GTPase in Striatal Synaptosomes by Denisova, Natalia A., Erat, Steven A., Kelly, Jeremiah F., Roth, George S.

“…Previous research has suggested that age-related decline in physiological functions may be the result of substantial alterations in membrane molecular…”
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Psychomotor Effects of Dopamine Infusion Under Decreased Glutathione Conditions by Shukitt-Hale, Barbara, Denisova, Natalia A., Strain, Joy G., Joseph, James A.

“…Administration of buthionine sulfoximine (BSO) selectively inhibits glutathione (GSH) biosynthesis, thereby inducing a GSH deficiency. Because GSH plays a…”
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Copernicus revisited : Amyloid beta in Alzheimer's disease. Commentaries. Author's reply by JOSEPH, James, SHUKITT-HALE, Barbara, LORING, Jeanne F, MORGAN, Dave, DENISOVA, Natalia A, MARTIN, Antonio, PERRY, George, SMITH, Mark A, COLE, Greg M, FRAUTSCHY, Sally A, NEVE, Rachael L, TERRY, Robert D

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Partial restoration of impaired alpha1-adrenergic responsiveness in parotid cells of aged rats by S-adenosylmethionine treatment by Kowatch, Mary Ann, Kelly, Jeremiah F., Denisova, Natalia A., Roth, George S.

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Dissociation of striatal GTPase and dopamine release responses to muscarinic cholinergic agonists in F344 rats: influence of age and dietary manipulation by Kelly, J F, Joseph, J A, Denisova, N A, Erat, S, Mason, R P, Roth, G S

“…There is evidence that dietary lipids and age both influence neuronal membrane composition and receptor G protein-linked signal transduction, but very little…”
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Age-Related Impairment in Striatal Muscarinic Cholinergic Signal Transduction Is Associated with Reduced Membrane Bilayer Width Measured by Small Angle X-Ray Diffraction by Kelly, J.F., Mason, R.P., Denisova, N.A., Joseph, J.A., Erat, S., Roth, G.S.

“…In order to determine whether age-related changes in neuronal membrane structure contribute to previously reported changes in muscarinic cholinergic signal…”
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