Search Results - "Denisov, Vladimir P."

Sequence-Specific Binding of Counterions to B-DNA by Denisov, Vladimir P., Halle, Bertil

“…Recent studies by x-ray crystallography, NMR, and molecular simulations have suggested that monovalent counterions can penetrate deeply into the minor groove…”
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Stabilization of Internal Charges in a Protein: Water Penetration or Conformational Change? by Denisov, Vladimir P., Schlessman, Jamie L., García-Moreno E., Bertrand, Halle, Bertil

“…The ionizable amino acid side chains of proteins are usually located at the surface. However, in some proteins an ionizable group is embedded in an apolar…”
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Using buried water molecules to explore the energy landscape of proteins by Denisov, Vladimir P, Peters, Jörg, Hörlein, Hans Dietrich, Halle, Bertil

“…Buried water molecules constitute a highly conserved, integral part of nearly all known protein structures. Such water molecules exchange with external solvent…”
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Proton NMR of 15N-Choline Metabolites Enhanced by Dynamic Nuclear Polarization by Sarkar, Riddhiman, Comment, Arnaud, Vasos, Paul R., Jannin, Sami, Gruetter, Rolf, Bodenhausen, Geoffrey, Hall, Hélène, Kirik, Deniz, Denisov, Vladimir P.

“…Chemical shifts of protons can report on metabolic transformations such as the conversion of choline to phosphocholine. To follow such processes in vivo,…”
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Residence times of the buried water molecules in bovine pancreatic trypsin inhibitor and its G36S mutant by Denisov, Vladimir P, Halle, Bertil, Peters, Joerg, Hoerlein, Hans Dietrich

“…The three-dimensional structure of the bovine pancreatic trypsin inhibitor (BPTI) contains 4 internal water molecules, denoted W111, W112, W113, and W122, the…”
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Competitive Na+ and Rb+ Binding in the Minor Groove of DNA by Cesare Marincola, Flaminia, Denisov, Vladimir P, Halle, Bertil

“…Sequence-dependent coordination of alkali ions to the nucleotide bases in the minor groove of AT-tract B-DNA has recently been inferred from X-ray…”
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Dynamics of the Internal and External Hydration of Globular Proteins by Denisov, Vladimir P, Halle, Bertil

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Protein hydration dynamics in aqueous solution by Denisov, V P, Halle, B

“…Water oxygen-17 and deuteron spin relaxation rates, measured as a function of resonance frequency, have been used to study the dynamics of protein hydration in…”
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Protein Hydration Dynamics in Aqueous Solution: A Comparison of Bovine Pancreatic Trypsin Inhibitor and Ubiquitin by Oxygen-17 Spin Relaxation Dispersion by Denisov, Vladimir P., Halle, Bertil

“…Water oxygen-17 spin relaxation was used to study hydration and dynamcs of the globular proteins bovine pancreatic trypsin inhibitor (BPTI) and ubiquitin in…”
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Hydrogen exchange rates in proteins from water (1)H transverse magnetic relaxation by Denisov, Vladimir P, Halle, Bertil

“…Access to the fast exchange kinetics of labile protein hydrogens in solution is provided by exchange broadening of the water 1H NMR line. We analyzed the…”
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Orientational Disorder and Entropy of Water in Protein Cavities by Denisov, Vladimir P, Venu, Kandadai, Peters, Jörg, Hörlein, Hans Dietrich, Halle, Bertil

“…Water 17O, 2H, and 1H nuclear magnetic relaxation dispersion (NMRD) data are presented for the Y35G mutant of bovine pancreatic trypsin inhibitor (BPTI) in…”
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Hydrogen Exchange Rates in Proteins from Water 1H Transverse Magnetic Relaxation by Denisov, Vladimir P, Halle, Bertil

“…Access to the fast exchange kinetics of labile protein hydrogens in solution is provided by exchange broadening of the water 1H NMR line. We analyzed the…”
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Hydration of denatured and molten globule proteins by Halle, Bertil, Denisov, Vladimir P, Jonsson, Bengt-Harald

“…The hydration of nonnative states is central to protein folding and stability but has been probed mainly by indirect methods. Here we use water 17O relaxation…”
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Accelerated Exchange of a Buried Water Molecule in Selectively Disulfide-Reduced Bovine Pancreatic Trypsin Inhibitor by Denisov, Vladimir P, Peters, Jörg, Hörlein, Hans Dietrich, Halle, Bertil

“…Using magnetic relaxation dispersion (MRD), we have previously shown that the four internal water molecules in bovine pancreatic trypsin inhibitor (BPTI)…”
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Direct Observation of Calcium-Coordinated Water in Calbindin D9k by Nuclear Magnetic Relaxation Dispersion by Denisov, Vladimir P, Halle, Bertil

“…The frequency dispersions of the water super(17)O and super(2)H nuclear magnetic relaxation rates have been measured in solutions of the calcium-binding…”
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Dissection of the structural and functional role of a conserved hydration site in RNase T1 by LANGHORST, ULRIKE, LORIS, REMY, DENISOV, VLADIMIR P., DOUMEN, JAN, ROOSE, PATRICE, MAES, DOMINIQUE, HALLE, BERTIL, STEYAERT, JAN

“…The reoccurrence of water molecules in crystal structures of RNase T1 was investigated. Five waters were found to be invariant in RNase T1 as well as in six…”
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Water 1H Magnetic Relaxation Dispersion in Protein Solutions. A Quantitative Assessment of Internal Hydration, Proton Exchange, and Cross-Relaxation by Venu, Kandadai, Denisov, Vladimir P, Halle, Bertil

“…The dispersion of the water 1H longitudinal relaxation rate in the frequency range 2−100 MHz has been measured in aqueous solutions of bovine pancreatic…”
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Dynamics of Functional Water in the Active Site of Native Carbonic Anhydrase from 17O Magnetic Relaxation Dispersion by Denisov, Vladimir P, Jonsson, Bengt-Harald, Halle, Bertil

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Thermal Denaturation of Ribonuclease A Characterized by Water 17O and 2H Magnetic Relaxation Dispersion by Denisov, Vladimir P, Halle, Bertil

“…Water oxygen-17 and deuteron nuclear magnetic relaxation dispersion (NMRD) measurements were used to characterize ribonuclease A (RNase A) in the course of…”
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Water molecules in DNA recognition I: hydration lifetimes of trp operator DNA in solution measured by NMR spectroscopy 1 1Edited by B. Honig by Sunnerhagen, Maria, Denisov, Vladimir P, Venu, Kandadai, Bonvin, Alexandre M.J.J, Carey, Jannette, Halle, Bertil, Otting, Gottfried

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