Search Results - "Denisenko, N P"

The frequency of CYP2C19 genetic polymorphisms in Russian patients with peptic ulcers treated with proton pump inhibitors by Sychev, D A, Denisenko, N P, Sizova, Z M, Grachev, A V, Velikolug, K A

“…Proton pump inhibitors, which are widely used as acid-inhibitory agents for the treatment of peptic ulcers, are mainly metabolized by 2C19 isoenzyme of…”
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Patients’ Pharmacogenetic Characteristics and the Risk of Adverse Reactions to Non-steroidal Anti-inflammatory Drugs: Case Reports by Zhiryakova, A. S., Denisenko, N. P., Kryukov, A. V., Akmalova, K. A., Tuchkova, S. N., Mirzaev, K. B., Sychev, D. A.

“…INTRODUCTION.  The variability in patient response to non-steroidal anti-inflammatory drugs (NSAIDs) may be due to genetic polymorphisms…”
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Pharmacogenetic Markers of Favipiravir Safety in COVID-19 Treatment by Temirbulatov, I. I., Kryukov, A. V., Mirzaev, K. B., Denisenko, N. P., Abdullaev, S. P., Petrova, A. V., Tkach, E. P., Shipacheva, A. V., Sychev, D. A.

“…The aim of the study was to evaluate the associations of different variants of AOX1 and CYP1A2 genes with safety parameters of favipiravir therapy in patients…”
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Features of drug-drug interactions rivaroxaban and calcium channel blockers depending on the ABCB1 genotype (rs1045642 and rs4148738) in patients 80 years of age and older with non-valvular atrial fibrillation by Sychev, D. A., Mirzaev, K. B., Cherniaeva, M. S., Shakhgildyan, N. V., Abdullaev, Sh. P., Denisenko, N. P., Sozaeva, Zh. A., Kachanova, A. A., Shastina, V. R., Gorbatenkova, S. V.

“…Background . The use of P-glycoprotein (P-gp) inhibitors and carriage of certain ABCB1 polymorphisms can lead to increased concentrations of rivaroxaban and…”
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The rs11385942 and rs657152 variants are not associated with COVID-19 severity and outcomes in patients treated with favipiravir and remdesivir by Abdullaev, Sh. P., Denisenko, N. P., Temirbulatov, I. I., Kachanova, A. A., Tuchkova, S. N., Mikhaylenko, E. V., Kryukov, A. V., Valiev, T. T., Mirzaev, K. B., Sychev, D. A.

“…Background . There is a mounting evidence in the scientific literature that susceptibility to SARS-CoV-2 infection could vary. The severity of COVID-19…”
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The Effect of Carriage of CYP3A53 and CYP3A422 Polymorphic Variants on the Safety of Remdesivir Therapy in Patients with COVID-19 by TEMIRBULATOV, I. I., KRYUKOV, A. V., MIRZAEV, K. B., DENISENKO, N. P., ABDULLAEV, S. P., ZHIRYAKOVA, A. S., SHEVCHUK, Y. V., VECHORKO, V. I., AVERKOV, O. V., SYCHEV, D. A.

“…The aim of the study was to assess the association of polymorphic variants CYP3A5*3 6986 A>G rs776746 and CYP3A4*22 rs35599367 C>T with the safety parameters…”
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Clinical Signs and Medical History as Predictors of Enalapril-Associated Dry Cough in Cardiovascular Patients by Sychev, I. V., Denisenko, N. P., Kachanova, A. A., Lapshtaeva, A. V., Abdullaev, Sh. P., Goncharova, L. N., Mirzaev, K. B., Sychev, D. A.

“…Angiotensin-converting enzyme inhibitors (ACEIs) are among the most prescribed and effective medicinal products for the treatment of several cardiovascular…”
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Model for predicting risk of developing drug-induced liver injury during remdesivir therapy: observational prospective open case-control study by Shevchuk, Yu. V., Kryukov, A. V., Temirbulatov, I. I., Sychev, I. V., Mirzaev, K. B., Denisenko, N. P., Abdullaev, Sh. P., Tuchkova, S. N., Vechorko, V. I., Averkov, O. V., Sychev, D. A.

“…Remdesivir is a drug widely used for the etiotropic treatment of COVID-19. According to a number of studies, the incidence of adverse reactions during…”
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Safety of Pharmacotherapy in COVID-19 Patients: A Literature Review by Kryukov, A. V., Zhiryakova, A. S., Shevchuk, Yu. V., Matveev, A. V., Vechorko, V. I., Averkov, O. V., Glagolev, S. V., Temirbulatov, I. I., Mirzaev, K. B., Denisenko, N. P., Abdullaev, Sh. P., Sychev, D. A.

“…The safety of COVID-19 pharmacotherapy is a relevant issue, first of all, because of the current lack of experience with using particular medicinal products…”
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Structure of the distribution of genetic determinants of the efficacy and safety of non-steroidal anti-inflammatory drugs in the Russian population: focus on CYP2C8, PTGS1 and PTGS2 by Denisenko, N. P., Abdullaev, Sh. P., Akmalova, K. A., Sozaeva, Zh. A., Kachanova, A. A., Sozaeva, M. S-Kh, Bolieva, L. Z., Grishina, E. A., Sychev, D. A.

“…The efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) may be determined by the polymorphic nature of the CYP2C8, PTGS1 and PTGS2 genes…”
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Efficiency of treatment of laryngopharyngeal reflux with proton pump inhibitors depending on the CYP2C19 polymorphism by Angotoeva, I. B., Denisenko, N. P., Sychev, D. A., Schepkina, E. V., Magomedova, M. M.

“…Introduction . A treatment for LFR for many years, the superiority of PPIs over placebos is still controversial. Of particular clinical importance is the…”
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Pharmacogenetic Aspects of Postoperative Anesthesia with Ketoprofen in Cardiac Surgery Patients by Morozova, T. E., Shatsky, D. A., Shikh, N. V., Shikh, E. V., Andrushchyshina, T. B., Lukina, M. V., Kachanova, A. A., Sozaeva, Z. A., Shuev, G. N., Denisenko, N. P., Grishina, E. А., Sychev, D. A.

“…Aim. Evaluation of the effect of polymorphisms of the CYP2D6, CYP2C8 genes on the efficacy and safety of postoperative analgesia with ketoprofen in patients…”
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Evaluation of the Influence of CYP2C9 2, CYP2C93 Gene Polymorphisms on the Efficacy and Safety of Postoperative Analgesia with Ketoprofen in Patients after Cardiac Surgery by Morozova, T. E., Shatsky, D. A., Shikh, N. V., Shikh, E. V., Andrushchyshina, T. B., Lukina, M. V., Kachanova, A. A., Sozaeva, Zh. A., Shuev, G. N., Denisenko, N. P., Grishina, E. A., Sychev, D. A.

“…Aim. The aim of the study was to evaluate the efficacy and safety of ketoprofen as an analgesic therapy in patients with CYP2C9*2 (430C>T) r s179985 and…”
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Effect of polymorphisms in CYP3A422 (rs35599367) C>T, CYP3A53 (rs776746) A>G, ABCB1 (rs4148738) C>T and ABCB1 (rs1045642) C>T genes on apixaban anticoagulation: pilot study results by Sychev, I. N., Fedina, L. V., Osipov, A. S., Temirbulatov, I. I., Tataroy, O. Yu, Sozaeva, Zh. A., Akmalova, K. A., Denisenko, N. P., Abdullaev, S. P., Kachanova, A. A., Grishina, E. A., Mirzaev, K. B., Sychev, D. A.

“…Introduction . Apixaban is a direct oral anticoagulant prescribed for treatment and prevention of venous thromboembolism (VTE) and for prevention of stroke in…”
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Correlation of 1846G > A Polymorphism of CYP2D6 Gene with Haloperidol Efficacy and Safety in Patients with Alcoholic Hallucinoses by Parkhomenko, A A, Zastrozhin, M S, Skryabin, VYu, Ivanchenko, V A, Pozdniakov, S A, Noskov, V V, Zaytsev, I A, Denisenko, N P, Akmalova, K A, Bryun, E A, Sychev, D A

“…Previous studies have shown that haloperidol biotransformation occurs with participation of the CYP2D6 isoenzyme. The CYP2D6 gene is highly polymorphic, which…”
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Association of CYP2D64 Polymorphism with the Steady-State Concentration of Haloperidol in Patients with Alcohol-Induced Psychotic Disorders by Parkhomenko, A A, Zastrozhin, M S, Pozdnyakov, S A, Noskov, V V, Zaytsev, I A, Ivanchenko, V A, Denisenko, N P, Akmalova, K A, Skryabin, VYu, Bryun, E A, Sychev, D A

“…CYP2D6 subfamily isoenzymes play an important role in the biotransformation of haloperidol, and their activity may influence the efficacy and safety of…”
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Lanczos τ-method regularization algorithm and its algebraic-programming implementation by Denisenko, P. N.

“…An algebraic algorithm is developed for computing an algebraic polynomial y n of order n ∈ N in computer algebra systems. This polynomial is the optimal…”
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Effect of omeprazole on the hypotensive efficacy of amlodipine depending on the genetic characteristics of patients by M. N. Dorofeeva, Zh. M. Sizova, E. V. Shikh, N. I. Lapidus, K. A. Ryzhikova, N. P. Denisenko, E. A. Grishina, D. A. Sychev

“…Features of anti-hypertensive therapy amlodipiny at patients with the arterial hypertonia (AH) with comorbid pathology  – kislotozavisimy diseases (KZZ),…”
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EFFECT OF CYP2C19 GENETIC POLYMORPHISMS ON THE EFFICACY OF PROTON PUMP INHIBITOR-BASED TRIPLE ERADICATION THERAPY IN SLAVIC PATIENTS WITH PEPTIC ULCERS: A META-ANALYSIS by Denisenko, N P, Sychev, D A, Sizova, Zh M, Rozhkov, A V, Kondrashov, A V

“…Several meta-analyzes reported the effect of CYP2C19 genetic polymorphisms on the efficacy of proton pump inhibitor-based triple therapy for Helicobacter…”
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THE PHARMACOKINETICS OF APIXABAN IN PATIENTS WITH CARDIOEMBOLIC STROKE IN ACUTE PHASE by Kryukov, A. V., Sychev, D. A., Andreev, D. A., Ryabova, A. V., Denisenko, N. P., Loskutnikov, M. A., Vinogradov, O. I., Domashenko, M. A.

“…Aim. To study pharmacokinetics of apixaban in patients with atrial fibrillation and cardioembolic stroke in acute phase. Material and methods. 17 patients (14…”
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