Search Results - "Denis Clay"

Effectiveness of a New App in Improving Oral Hygiene in Orthodontic Patients: A Pilot Study by Lopes dos Santos, Raquel, Spinola, Manuela da Silva, Carvalho, Ellen, Lopes dos Santos, Denis Clay, Dame-Teixeira, Naile, Heller, Debora

“…The aim of this randomised clinical trial was to evaluate the effects of a mobile application (app) on the oral hygiene (OH) of adolescents undergoing fixed…”
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Mesenchymal stromal cells confer chemoresistance to myeloid leukemia blasts through Side Population functionality and ABC transporter activation by Boutin, Laetitia, Arnautou, Pierre, Trignol, Aurélie, Ségot, Amandine, Farge, Thomas, Desterke, Christophe, Soave, Sabrina, Clay, Denis, Raffoux, Emmanuel, Sarry, Jean-Emmanuel, Malfuson, Jean-Valère, Lataillade, Jean-Jacques, Le Bousse-Kerdilès, Marie-Caroline, Anginot, Adrienne

“…Targeting chemoresistant malignant cells is one of the current major challenges in oncology. Therefore, it is mandatory to refine the characteristics of these…”
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Long-lasting inhibitory effects of fetal liver mesenchymal stem cells on T-lymphocyte proliferation by Giuliani, Massimo, Fleury, Maud, Vernochet, Amelia, Ketroussi, Farah, Clay, Denis, Azzarone, Bruno, Lataillade, Jean Jacques, Durrbach, Antoine

“…Human bone marrow mesenchymal stem cells (BM-MSC) are multipotent progenitor cells that have transient immunomodulatory properties on Natural Killer (NK)…”
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Lipoplexes Targeting the CD44 Hyaluronic Acid Receptor for Efficient Transfection of Breast Cancer Cells by Surace, Claudio, Arpicco, Silvia, Dufaÿ-Wojcicki, Amélie, Marsaud, Véronique, Bouclier, Céline, Clay, Denis, Cattel, Luigi, Renoir, Jack-Michel, Fattal, Elias

“…Lipoplexes containing a hyaluronic acid−dioleoylphosphatidylethanolamine (HA−DOPE) conjugate were designed to target the CD44 receptor on breast cancer cells…”
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Endothelial and hematopoietic hPSCs differentiation via a hematoendothelial progenitor by Vargas-Valderrama, Alejandra, Ponsen, Anne-Charlotte, Le Gall, Morgane, Clay, Denis, Jacques, Sébastien, Manoliu, Tudor, Rouffiac, Valérie, Ser-le-Roux, Karine, Quivoron, Cyril, Louache, Fawzia, Uzan, Georges, Mitjavila-Garcia, Maria-Teresa, Oberlin, Estelle, Guenou, Hind

“…Background hPSC-derived endothelial and hematopoietic cells (ECs and HCs) are an interesting source of cells for tissue engineering. Despite their close…”
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Monoclonal antibody 1.6.1 against human MPL receptor allows HSC enrichment of CB and BM CD34+ CD38− populations by Petit Cocault, Laurence, Fleury, Maud, Clay, Denis, Larghero, Jérôme, Vanneaux, Valérie, Souyri, Michèle

“…Thrombopoietin (TPO) and its receptor Mpl (CD110) play a crucial role in the regulation of hematopoietic stem cells (HSCs). Functional study of Mpl-expressing…”
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Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia by Domenech, Carine, Maillard, Loïc, Rousseau, Alix, Guidez, Fabien, Petit, Laurence, Pla, Marika, Clay, Denis, Guimiot, Fabien, Sanfilippo, Sandra, Jacques, Sebastien, de la Grange, Pierre, Robil, Noémie, Soulier, Jean, Souyri, Michèle

“…Fanconi anemia (FA) causes bone marrow failure early during childhood, and recent studies indicate that a hematopoietic defect could begin in utero. We…”
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Stromal cell–derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G0/G1 transition in CD34+ cells: evidence for an autocrine/paracrine mechanism by Lataillade, Jean-Jacques, Clay, Denis, Bourin, Philippe, Hérodin, Françis, Dupuy, Catherine, Jasmin, Claude, Le Bousse-Kerdilès, Marie-Caroline

“…The stromal cell–derived factor 1 (SDF-1) chemokine has various effects on hematopoietic cell functions. Its role in migration and homing of hematopoietic…”
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Rapid Isolation of Rare Isotype-Switched Hybridoma Variants: Application to the Generation of IgG2a and IgG2b MAb to CD63, a Late Endosome and Exosome Marker by Charrin, Stéphanie, Palmulli, Roberta, Billard, Martine, Clay, Denis, Boucheix, Claude, Van Niel, Guillaume, Rubinstein, Eric

“…CD63, a member of the tetraspanin superfamily, is used as a marker of late endosomes and lysosome-related organelles, as well as a marker of exosomes. Here, we…”
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ERK1 regulates the hematopoietic stem cell niches by Saulnier, Nathalie, Guihard, Soizic, Holy, Xavier, Decembre, Elodie, Jurdic, Pierre, Clay, Denis, Feuillet, Vincent, Pagès, Gilles, Pouysségur, Jacques, Porteu, Françoise, Gaudry, Murielle

“…The mitogen-activated protein kinases (MAPK) ERK1 and ERK2 are among the major signal transduction molecules but little is known about their specific functions…”
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Integration-deficient lentivectors: an effective strategy to purify and differentiate human embryonic stem cell-derived hepatic progenitors by Yang, Guanghua, Si-Tayeb, Karim, Corbineau, Sébastien, Vernet, Rémi, Gayon, Régis, Dianat, Noushin, Martinet, Clémence, Clay, Denis, Goulinet-Mainot, Sylvie, Tachdjian, Gérard, Burks, Deborah, Vallier, Ludovic, Bouillé, Pascale, Dubart-Kupperschmitt, Anne, Weber, Anne

“…Human pluripotent stem cells (hPSCs) hold great promise for applications in regenerative medicine. However, the safety of cell therapy using differentiated…”
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Dual SP/ALDH Functionalities Refine the Human Hematopoietic Lin−CD34+CD38− Stem/Progenitor Cell Compartment by Pierre‐Louis, Olivier, Clay, Denis, Brunet de la Grange, Philippe, Blazsek, Istvan, Desterke, Christophe, Guerton, Bernadette, Blondeau, Camille, Malfuson, Jean‐Valère, Prat, Marie, Bennaceur‐Griscelli, Annelise, Lataillade, Jean‐Jacques, Le Bousse‐Kerdilès, Marie‐Caroline

“…Identification of prevalent specific markers is crucial to stem/progenitor cell purification. Determinants such as the surface antigens CD34 and CD38 are…”
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Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis by Desterke, Christophe, Martinaud, Christophe, Guerton, Bernadette, Pieri, Lisa, Bogani, Costanza, Clay, Denis, Torossian, Frederic, Lataillade, Jean-Jacques, Hasselbach, Hans C, Gisslinger, Heinz, Demory, Jean-Loup, Dupriez, Brigitte, Boucheix, Claude, Rubinstein, Eric, Amsellem, Sophie, Vannucchi, Alessandro M, Le Bousse-Kerdilès, Marie-Caroline

“…Primary myelofibrosis is characterized by clonal myeloproliferation, dysmegakaryopoiesis, extramedullary hematopoiesis associated with myelofibrosis and…”
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Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia by Charrad, Rachida-Sihem, Li, Yue, Delpech, Bertrand, Balitrand, Nicole, Clay, Denis, Jasmin, Claude, Chomienne, Christine, Smadja-Joffe, Florence

“…Blockage in myeloid differentiation characterizes acute myeloid leukemia (AML); the stage of the blockage defines distinct AML subtypes (AML1/2 to AML5)…”
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CD19 Is Linked to the Integrin-associated Tetraspans CD9, CD81, and CD82 by Horváth, György, Serru, Valérie, Clay, Denis, Billard, Martine, Boucheix, Claude, Rubinstein, Eric

“…The CD19-CD21-CD81 complex regulates signal transduction events critical for B lymphocyte development and humoral immunity. CD81, a molecule with 4…”
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Phenotypic and functional characteristics of CD34+ cells are related to their anatomical environment: is their versatility a prerequisite for their bio-availability? by Lataillade, Jean‐Jacques, Clay, Denis, David, Catherine, Boutin, Laetitia, Guerton, Bernadette, Drouet, Michel, Hérodin, Françis, Le Bousse‐Kerdilès, Marie‐Caroline

“…Human CD34+ hematopoietic progenitors (HP) are mainly resident in adult bone marrow (BM). However, their recent revelation in nonhematopoietic tissues implies…”
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BCR::ABL1 -Dependent Promotion of Hematopoietic Stem Cells (HSC) and Progenitors in an Inducible Embryonic Stem Cell (ESC) Model by Artus, Jerome, Zench, Alina, Simanic, Isidora, Desterke, Christophe, Clay, Denis, de Souza, Lucas, Coignard, Sabrina, Bennaceur Griscelli, Annelise, Turhan, Ali G, Foudi, Adlen

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BCR-ABL promotes hematopoietic stem and progenitor cell formation in embryonic stem cells by Artus, Jérôme, Zenych, Alina, Simanic, Isidora, Desterke, Christophe, Clay, Denis, Saïm, Sonia, Ijjeh, Yousef, de Souza, Lucas Eduardo Botelho, Coignard, Sabrina, Bennaceur-Griscelli, Annelise, Turhan, Ali G., Foudi, Adlen

“…•BCR-ABL promotes the formation of hematopoietic stem cells (HSPCs) from an inducible murine embryonic stem cell model.•BCR-ABL favors the emergence and…”
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Phenotypic diversity in human fibroblasts from myelometaplasic and non‐myelometaplasic hematopoietic tissues by Brouty‐Boyé, Danièle, Doucet, Christelle, Clay, Denis, Le Bousse‐Kerdiles, Marie‐Caroline, Lampidis, Théodore J., Azzarone, Bruno

“…Fibroblasts from a variety of tissues interact with and influence the behavior of the cell types they are associated with by producing specific proteins that…”
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Bistable Epigenetic States Explain Age‐Dependent Decline in Mesenchymal Stem Cell Heterogeneity by Hamidouche, Zahia, Rother, Karen, Przybilla, Jens, Krinner, Axel, Clay, Denis, Hopp, Lydia, Fabian, Claire, Stolzing, Alexandra, Binder, Hans, Charbord, Pierre, Galle, Joerg

“…The molecular mechanisms by which heterogeneity, a major characteristic of stem cells, is achieved are yet unclear. We here study the expression of the…”
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