Search Results - "Denis, Caroline"
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In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model
Published in International journal of pharmaceutics (14-02-2012)“…The biodistribution of intravenously injected DNA lipid nanocapsules (DNA LNCs), encapsulating pHSV-tk, was analysed by in vivo imaging on an orthotopic…”
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Evaluation of New Fluorescent Lipophosphoramidates for Gene Transfer and Biodistribution Studies after Systemic Administration
Published in International journal of molecular sciences (02-11-2015)“…The objective of lung gene therapy is to reach the respiratory epithelial cells in order to deliver a functional nucleic acid sequence. To improve the…”
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3
Acute hypoxic hepatitis ('liver shock'): still a frequently overlooked cardiological diagnosis
Published in European journal of heart failure (01-08-2004)“…The diagnosis of acute hypoxic hepatitis remains problematic. We describe a series of 14 patients who were initially hospitalized in an hepatic care unit with…”
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Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells
Published in Cell (13-12-2018)“…Checkpoint inhibitors have revolutionized cancer treatment. However, only a minority of patients respond to these immunotherapies. Here, we report that…”
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5
P-067 - Site-selective 18F-labelling of octreotide via disulfide rebridging
Published in Nuclear medicine and biology (01-05-2022)Get full text
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Site-selective 18F-labelling of octreotide via disulfide rebridging
Published in Nuclear medicine and biology (01-05-2022)Get full text
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7
Sonoporation-assisted micelle delivery in subcutaneous glioma-bearing mice evaluated by PET/fluorescent bi-modal imaging
Published in Nanoscale (03-08-2023)“…Tumor-specific drug delivery is a major challenge for the pharmaceutical industry. Nanocarrier systems have been widely investigated to increase and control…”
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Tumor-Targeted Perfluorinated Micelles as Efficient Theranostic Agents Combining Positron Emission Tomography and Radiosensitization
Published in ACS applied materials & interfaces (01-05-2024)“…We report the synthesis of biocompatible perfluorinated micelles designed to improve radiotherapeutic efficacy in a radioresistant tumor environment. In vitro…”
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Fluorine-18 and Radiometal Labeling of Biomolecules via Disulfide Rebridging
Published in Bioconjugate chemistry (15-11-2023)“…Biomolecules labeled with positron-emitting radionuclides like fluorine-18 or radiometals like copper-64 and zirconium-89 are increasingly employed in nuclear…”
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Design, Radiosynthesis, and Evaluation of New Fluorinated Analogs of MeDAS for Myelin PET Imaging
Published in Journal of medicinal chemistry (22-06-2023)“…Positron emission tomography (PET) imaging of the myelin sheath is a powerful tool to investigate multiple sclerosis, monitor its evolution, and support drug…”
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ImmunoPET imaging–based pharmacokinetic profiles of an antibody and its Fab targeting endothelin A receptors on glioblastoma stem cells in a preclinical orthotopic model
Published in European journal of nuclear medicine and molecular imaging (01-09-2023)“…Background The resistance of glioblastoma stem cells (GSCs) to treatment is one of the causes of glioblastoma (GBM) recurrence. Endothelin A receptor (ET A )…”
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P-073 - Synthesis, radiolabeling and fluorescence imaging of new fluorine-18 derivatives of MeDAS for PET imaging of demyelination
Published in Nuclear medicine and biology (01-05-2022)Get full text
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Synthesis, radiolabeling and fluorescence imaging of new fluorine-18 derivatives of MeDAS for PET imaging of demyelination
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14
Pharmacokinetics derived from PET imaging of inspiring radio-enhancer platinum nanoparticles
Published in Nanomedicine (01-11-2022)“…Personalized medicine approach in radiotherapy requires the delivery of precise dose to the tumor. The concept is to increase the effectiveness of radiotherapy…”
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Low-boiling-point perfluorocarbon nanodroplets for adaptable ultrasound-induced blood-brain barrier opening
Published in Journal of controlled release (01-12-2024)“…Low-boiling point perfluorocarbon nanodroplets (NDs) are valued as effective sonosensitive agents, encapsulating a liquid perfluorocarbon that would…”
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Pharmacokinetics derived from PET imaging of inspiring radio-enhancer platinum nanoparticles
Published in Nanomedicine (01-11-2022)Get full text
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17
A cancer immunoprofiling strategy using mass spectrometry coupled with bioorthogonal cleavage
Published in Chemical science (Cambridge) (17-10-2024)“…The accurate quantification of biomarkers is paramount in modern medicine, particularly in cancer where precise diagnosis is imperative for targeted therapy…”
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Preoperative PET imaging and fluorescence-guided surgery of human glioblastoma using dual-labeled antibody targeting ETA receptors in a preclinical mouse model: A theranostic approach
Published in Theranostics (30-09-2024)“…Rationale: Glioblastoma (GBM) poses significant challenges regarding complete tumor removal due to its heterogeneity and invasiveness, emphasizing the need for…”
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Preoperative PET imaging and fluorescence-guided surgery of human glioblastoma using dual-labeled antibody targeting ET A receptors in a preclinical mouse model: A theranostic approach
Published in Theranostics (2024)“…Glioblastoma (GBM) poses significant challenges regarding complete tumor removal due to its heterogeneity and invasiveness, emphasizing the need for effective…”
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Cationic lipophosphoramidates with two disulfide motifs: synthesis, behaviour in reductive media and gene transfection activity
Published in Organic & biomolecular chemistry (13-02-2013)“…Lipophosphoramidates have previously been identified as efficient vectors for gene delivery. The incorporation of functional groups that respond to a…”
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