Search Results - "Denham, Steven"

How Environmental Fungi Cause a Range of Clinical Outcomes in Susceptible Hosts by Denham, Steven T., Wambaugh, Morgan A., Brown, Jessica C.S.

“…Environmental fungi are globally ubiquitous and human exposure is near universal. However, relatively few fungal species are capable of infecting humans, and…”
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Mechanisms of Pulmonary Escape and Dissemination by Cryptococcus neoformans by Denham, Steven T, Brown, Jessica C S

“…is a common environmental saprophyte and human fungal pathogen that primarily causes disease in immunocompromised individuals. Similar to many environmentally…”
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Synergistic and antagonistic drug interactions in the treatment of systemic fungal infections by Wambaugh, Morgan A, Denham, Steven T, Ayala, Magali, Brammer, Brianna, Stonhill, Miekan A, Brown, Jessica Cs

“…Invasive fungal infections cause 1.6 million deaths annually, primarily in immunocompromised individuals. Mortality rates are as high as 90% due to limited…”
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A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans by Denham, Steven T., Brammer, Brianna, Chung, Krystal Y., Wambaugh, Morgan A., Bednarek, Joseph M., Guo, Li, Moreau, Christian T., Brown, Jessica C.S.

“…Environmental pathogens move from ecological niches to mammalian hosts, requiring adaptation to dramatically different environments. Microbes that disseminate…”
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Regulated Release of Cryptococcal Polysaccharide Drives Virulence and Suppresses Immune Cell Infiltration into the Central Nervous System by Denham, Steven T, Verma, Surbhi, Reynolds, Raymond C, Worne, Colleen L, Daugherty, Joshua M, Lane, Thomas E, Brown, Jessica C S

“…is a common environmental yeast and opportunistic pathogen responsible for 15% of AIDS-related deaths worldwide. Mortality primarily results from…”
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Effect of Feeding Hay on Nonesterified Fatty Acids in Appetite-Suppressed Pregnant New Zealand White Rabbits by Veenstra, Jesse W, Filgo, Adam J, Denham, Steven C

“…Pregnant rabbits are a common nonrodent model for reproductive safety evaluation in preclinical drug development. During reproductive toxicology studies,…”
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Survey of Retail Milk Composition as Affected by Label Claims Regarding Farm-Management Practices by Vicini, John, PhD, Etherton, Terry, PhD, Kris-Etherton, Penny, PhD, RD, Ballam, Joan, MS, Denham, Steven, PhD, Staub, Robin, PhD, Goldstein, Daniel, MD, Cady, Roger, PhD, McGrath, Michael, PhD, Lucy, Matthew, PhD

“…Abstract A trend in food labeling is to make claims related to agricultural management, and this is occurring with dairy labels. A survey study was conducted…”
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Local evolution of pyrethroid resistance offsets gene flow among Aedes aegypti collections in Yucatan State, Mexico by Saavedra-Rodriguez, Karla, Beaty, Meaghan, Lozano-Fuentes, Saul, Denham, Steven, Garcia-Rejon, Julian, Reyes-Solis, Guadalupe, Machain-Williams, Carlos, Loroño-Pino, Maria Alba, Flores-Suarez, Adriana, Ponce-Garcia, Gustavo, Beaty, Barry, Eisen, Lars, Black, 4th, William C

“…The mosquito Aedes aegypti is the major vector of the four serotypes of dengue virus (DENV1-4). Previous studies have shown that Ae. aegypti in Mexico have a…”
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Lend Me Some Sugar: How Polysaccharides and Pleomorphism Drive the Dissemination of a Fungal Pathogen by Denham, Steven Thomas

“…Invasive mycoses pose an underappreciated but growing threat to global public health. Combined, they account for >1.5 million deaths annually with mortality…”
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Abstract 657: A New Translational Model of Hypercholesterolemia and Atherosclerosis: Effect of Statins on LDLR KO Miniature Swine by Mais, Dale E, Vihtelic, Thomas, Amuzie, Chidozie, Denham, Steven, Swart, John R, Rogers, Christopher S

“…Abstract only Small animal models of atherosclerosis are commonly used in drug studies; however, the results often fail to translate into the clinic. A large…”
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A Translational Model for Diet-related Atherosclerosis: Effect of Statins on Hypercholesterolemia and Atherosclerosis in a Minipig by Amuzie, Chidozie, Swart, John R., Rogers, Christopher S., Vihtelic, Thomas, Denham, Steven, Mais, Dale E.

“…Models of atherosclerosis are used in preclinical studies but often fail to translate to humans. A model that better reflects human atherosclerosis is…”
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Two Novel Bioassays to Assess the Effects of Pyrethroid-Treated Netting on Knockdown-Susceptible Versus Resistant Strains of Aedes aegypti by Denham, Steven, Eisen, Lars, Beaty, Meaghan, Beaty, Barry J, Black, 4th, William C, Saavedra-Rodriguez, Karla

“…We describe 2 new mosquito bioassays for use with insecticide-treated netting or other textiles. The 1st is a cylinder bioassay in which a mosquito is forced…”
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