Search Results - "Deng, Zhong‐Bin"

Interspecies communication between plant and mouse gut host cells through edible plant derived exosome‐like nanoparticles by Mu, Jingyao, Zhuang, Xiaoying, Wang, Qilong, Jiang, Hong, Deng, Zhong‐Bin, Wang, Baomei, Zhang, Lifeng, Kakar, Sham, Jun, Yan, Miller, Donald, Zhang, Huang‐Ge

“…SCOPE: Exosomes, small vesicles participating in intercellular communication, have been extensively studied recently; however, the role of edible plant derived…”
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Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway by Sriwastva, Mukesh K, Deng, Zhong‐Bin, Wang, Bomei, Teng, Yun, Kumar, Anil, Sundaram, Kumaran, Mu, Jingyao, Lei, Chao, Dryden, Gerald W, Xu, Fangyi, Zhang, Lifeng, Yan, Jun, Zhang, Xiang, Park, Juw Won, Merchant, Michael L, Egilmez, Nejat K, Zhang, Huang‐Ge

“…Bark protects the tree against environmental insults. Here, we analyzed whether this defensive strategy could be utilized to broadly enhance protection against…”
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Ginger-derived nanoparticles protect against alcohol-induced liver damage by Zhuang, Xiaoying, Deng, Zhong-Bin, Mu, Jingyao, Zhang, Lifeng, Yan, Jun, Miller, Donald, Feng, Wenke, McClain, Craig J., Zhang, Huang-Ge

“…Daily exposure of humans to nanoparticles from edible plants is inevitable, but significant advances are required to determine whether edible plant…”
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Targeted Drug Delivery to Intestinal Macrophages by Bioactive Nanovesicles Released from Grapefruit by Wang, Baomei, Zhuang, Xiaoying, Deng, Zhong-Bin, Jiang, Hong, Mu, Jingyao, Wang, Qilong, Xiang, Xiaoyu, Guo, Haixun, Zhang, Lifeng, Dryden, Gerald, Yan, Jun, Miller, Donald, Zhang, Huang-Ge

“…The gut mucosal immune system is considered to play an important role in counteracting potential adverse effects of food-derived antigens including…”
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Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids by Wang, Qilong, Zhuang, Xiaoying, Mu, Jingyao, Deng, Zhong-Bin, Jiang, Hong, Zhang, Lifeng, Xiang, Xiaoyu, Wang, Baomei, Yan, Jun, Miller, Donald, Zhang, Huang-Ge

“…Although the use of nanotechnology for the delivery of a wide range of medical treatments has potential to reduce adverse effects associated with drug therapy,…”
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Induction of myeloid‐derived suppressor cells by tumor exosomes by Xiang, Xiaoyu, Poliakov, Anton, Liu, Cunren, Liu, Yuelong, Deng, Zhong‐bin, Wang, Jianhua, Cheng, Ziqiang, Shah, Spandan V., Wang, Gui‐Jun, Zhang, Liming, Grizzle, William E., Mobley, Jim, Zhang, Huang‐Ge

“…Myeloid‐derived suppressor cells (MDSCs) promote tumor progression. The mechanisms of MDSC development during tumor growth remain unknown. Tumor exosomes…”
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Cathelicidin‐related antimicrobial peptide alleviates alcoholic liver disease through inhibiting inflammasome activation by Li, Fengyuan, Zhao, Cuiqing, Shao, Tuo, Liu, Yunhuan, Gu, Zelin, Jiang, Mengwei, Li, Huimin, Zhang, Lihua, Gillevet, Patrick M, Puri, Puneet, Deng, Zhong‐Bin, Chen, Shao‐Yu, Barve, Shirish, Gobejishvili, Leila, Vatsalya, Vatsalya, McClain, Craig J, Feng, Wenke

“…Alcoholic liver disease (ALD) is associated with gut dysbiosis and hepatic inflammasome activation. While it is known that antimicrobial peptides (AMPs) play a…”
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Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance by Deng, Zhong-bin, Poliakov, Anton, Hardy, Robert W, Clements, Ronald, Liu, Cunren, Liu, Yuelong, Wang, Jianhua, Xiang, Xiaoyu, Zhang, Shuangqin, Zhuang, Xiaoying, Shah, Spandan V, Sun, Dongmei, Michalek, Sue, Grizzle, William E, Garvey, Timothy, Mobley, Jim, Zhang, Huang-Ge

“…Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance Zhong-bin Deng 1 , Anton Poliakov 2 , Robert W. Hardy 3 ,…”
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Exosome‐Like Nanoparticles From Lactobacillus rhamnosus GG Protect Against Alcohol‐Associated Liver Disease Through Intestinal Aryl Hydrocarbon Receptor in Mice by Gu, Zelin, Li, Fengyuan, Liu, Yunhuan, Jiang, Mengwei, Zhang, Lihua, He, Liqing, Wilkey, Daniel W., Merchant, Michael, Zhang, Xiang, Deng, Zhong‐Bin, Chen, Shao‐Yu, Barve, Shirish, McClain, Craig J., Feng, Wenke

“…Alcohol‐associated liver disease (ALD) is a major cause of mortality. Gut barrier dysfunction–induced bacterial translocation and endotoxin release contribute…”
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Immature myeloid cells induced by a high‐fat diet contribute to liver inflammation by Deng, Zhong‐bin, Liu, Yuelong, Liu, Cunren, Xiang, Xiaoyu, Wang, Jianhua, Cheng, Ziqiang, Shah, Spandan V., Zhang, Shuangyin, Zhang, Liming, Zhuang, Xiaoying, Michalek, Sue, Grizzle, William E., Zhang, Huang‐Ge

“…Chronic inflammation plays a critical role in promoting obesity‐related disorders, such as fatty liver disease. The inflammatory cells that mediate these…”
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Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells by Deng, Zhong-Bin, Zhuang, Xiaoying, Ju, Songwen, Xiang, Xiaoyu, Mu, Jingyao, Liu, Yuelong, Jiang, Hong, Zhang, Lifeng, Mobley, James, McClain, Craig, Feng, Wenke, Grizzle, William, Yan, Jun, Miller, Donald, Kronenberg, Mitchell, Zhang, Huang-Ge

“…Regulation and induction of anergy in NKT cells of the liver can inhibit autoimmune and antitumor responses by mechanisms that are poorly understood. We…”
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Intestinal mucus‐derived nanoparticle–mediated activation of Wnt/β‐catenin signaling plays a role in induction of liver natural killer T cell anergy in mice by Deng, Zhong‐Bin, Zhuang, Xiaoying, Ju, Songwen, Xiang, Xiaoyu, Mu, Jingyao, Wang, Qilong, Jiang, Hong, Zhang, Lifeng, Kronenberg, Mitchell, Yan, Jun, Miller, Donald, Zhang, Huang‐Ge

“…The Wnt/β‐catenin pathway has been known to play a role in induction of immune tolerance, but its role in the induction and maintenance of natural killer T…”
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Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss by Ding, Ke-Hong, Wang, Zai-Zhao, Hamrick, Mark W., Deng, Zhong-Bin, Zhou, Li, Kang, Baolin, Yan, Sheng-Li, She, Jin-Xiong, Stern, David M., Isales, Carlos M., Mi, Qing-Sheng

“…The mechanisms underlying diabetes-mediated bone loss are not well defined. It has been reported that the advanced glycation endproducts (AGEs) and receptor…”
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Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis by Ju, Songwen, Mu, Jingyao, Dokland, Terje, Zhuang, Xiaoying, Wang, Qilong, Jiang, Hong, Xiang, Xiaoyu, Deng, Zhong-Bin, Wang, Baomei, Zhang, Lifeng, Roth, Mary, Welti, Ruth, Mobley, James, Jun, Yan, Miller, Donald, Zhang, Huang-Ge

“…Food-derived exosome-like nanoparticles pass through the intestinal tract throughout our lives, but little is known about their impact or function. Here, as a…”
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Exosomes are endogenous nanoparticles that can deliver biological information between cells by Sun, Dongmei, Zhuang, Xiaoying, Zhang, Shuangqin, Deng, Zhong-Bin, Grizzle, William, Miller, Donald, Zhang, Huang-Ge

“…Exosomal particular size of 30–100nm matches the size criterion for nanoparticles, and opens up the possibility of using exosomes as a nanoparticle drug…”
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Thymus Exosomes-Like Particles Induce Regulatory T Cells by Wang, Gui-Jun, Liu, Yuelong, Qin, Aijian, Shah, Spandan V, Deng, Zhong-bin, Xiang, Xiaoyu, Cheng, Ziqiang, Liu, Cunren, Wang, Jianhua, Zhang, Liming, Grizzle, William E, Zhang, Huang-Ge

“…Exosomes released from different types of cells have been proposed to contribute to intercellular communication. We report that thymic exosome-like particles…”
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The autoimmune regulator (Aire) controls iNKT cell development and maturation by Mi, Qing-Sheng, Deng, Zhong-Bin, Joshi, Sunil K, Wang, Zai-Zhao, Zhou, Li, Eckenrode, Sarah, Joshi, Ratanmani, Ly, Dalam, Yi, Bing, Delovitch, Terry L, She, Jin-Xiong

“…The mechanism underlying the autoimmune polyglandular syndrome type-1 (APS1) has been attributed to defective T-cell negative selection resulting from reduced…”
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Isolation, identification, and characterization of novel nanovesicles by Zhang, Huang-Ge, Cao, Pengxiao, Teng, Yun, Hu, Xin, Wang, Qilong, Yeri, Ashish S, Zhuang, Xiaoying, Samykutty, Abhilash, Mu, Jingyao, Deng, Zhong-Bin, Zhang, Lifeng, Mobley, James A, Yan, Jun, Van Keuren-Jensen, Kendall, Miller, Donald

“…Extracellular microvesicles (EVs) have been recognized for many potential clinical applications including biomarkers for disease diagnosis. In this study, we…”
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Persistent Hepatic Structural Alterations Following Nanoceria Vascular Infusion in the Rat by Tseng, Michael T., Fu, Qiang, Lor, Khoua, Fernandez-Botran, G. Rafael, Deng, Zhong-Bin, Graham, Uschi, Butterfield, D. Allan, Grulke, Eric A., Yokel, Robert A.

“…Understanding the long-term effects and possible toxicity of nanoceria, a widely utilized commercial metal oxide, is of particular importance as it is poised…”
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COP9-Associated CSN5 Regulates Exosomal Protein Deubiquitination and Sorting by Liu, Yuelong, Shah, Spandan V, Xiang, Xiaoyu, Wang, Jianhua, Deng, Zhong-bin, Liu, Cunren, Zhang, Liming, Wu, Jianming, Edmonds, Tara, Jambor, Christina, Kappes, John C, Zhang, Huang-Ge

“…Ubiquitinated endosomal proteins that are deposited into the lumens of multivesicular bodies are either sorted for lysosomal-mediated degradation or secreted…”
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