Search Results - "Deng, Yuanfei"
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Selective degradation of AR-V7 to overcome castration resistance of prostate cancer
Published in Cell death & disease (21-09-2021)“…Androgen receptor splice variant 7 (AR-V7), a form of ligand-independent and constitutively activating variant of androgen receptor (AR), is considered as the…”
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2
A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance
Published in Oncogene (24-06-2021)“…Prostate cancer (PC) is the second most common cancer with limited treatment option in males. Although the reactivation of embryonic signals in adult cells is…”
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3
TSPAN31 is a critical regulator on transduction of survival and apoptotic signals in hepatocellular carcinoma cells
Published in FEBS letters (01-09-2017)“…Tetraspanins are commonly believed to act as ‘molecular facilitators’, not directly involved in signal transduction. Tetraspanin 31 (TSPAN31), recently…”
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4
Integrated Analysis and Identification of Novel Biomarkers in Parkinson's Disease
Published in Frontiers in aging neuroscience (18-06-2018)“…Parkinson's disease (PD) is a quite common neurodegenerative disorder with a prevalence of approximately 1:800-1,000 in subjects over 60 years old. The aim of…”
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USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells
Published in Journal of experimental & clinical cancer research (21-06-2021)“…Hepatocellular carcinoma (HCC) remains a medical challenge due to its high proliferation and metastasis. Although deubiquitinating enzymes (DUBs) play a key…”
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Identification of novel biomarkers in ischemic stroke: a genome-wide integrated analysis
Published in BMC medical genetics (30-03-2020)“…Ischemic Stroke (IS) is the most common neurological emergency disease and has become the second most frequent cause of death after coronary artery disease in…”
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ARV-771 Acts as an Inducer of Cell Cycle Arrest and Apoptosis to Suppress Hepatocellular Carcinoma Progression
Published in Frontiers in pharmacology (04-05-2022)“…Hepatocellular carcinoma (HCC) is the most commonly diagnosed liver cancer with limited treatment options and extremely poor prognosis worldwide. Recently, the…”
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Comparison of genomic alterations in Epstein–Barr virus‐positive and Epstein–Barr virus‐negative diffuse large B‐cell lymphoma
Published in Cancer medicine (Malden, MA) (01-02-2024)“…Background Epstein–Barr virus (EBV)‐positive diffuse large B‐cell lymphoma (EBV‐posDLBCL) is an aggressive B‐cell lymphoma that often presents similar…”
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Functional L-Arginine Derivative as an Efficient Vector for Intracellular Protein Delivery for Potential Cancer Therapy
Published in Journal of functional biomaterials (30-05-2023)“…The utilization of cytosolic protein delivery is a promising approach for treating various diseases by replacing dysfunctional proteins. Despite the…”
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10
Development and Validation of a Predictive Nomogram for Possible REM Sleep Behavior Disorders
Published in Frontiers in neurology (29-06-2022)“…Objectives To develop and validate a predictive nomogram for idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) in a community population in…”
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Job Stress and Carotid Intima-media Thickness in Chinese Workers
Published in Journal of Occupational Health (01-09-2010)“…[Abstract]: Job Stress and Carotid Intima-media Thickness in Chinese Workers: Weixian XU, et al. Department of Cardiology, Peking University Third Hospital and…”
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Dual-Channel Adaptive Scale Hypergraph Encoders With Cross-View Contrastive Learning for Knowledge Tracing
Published in IEEE transaction on neural networks and learning systems (23-04-2024)“…Knowledge tracing (KT) refers to predicting learners' performance in the future according to their historical responses, which has become an essential task in…”
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Improving semantic similarity computation via subgraph feature fusion based on semantic awareness
Published in Engineering applications of artificial intelligence (01-10-2024)“…Semantic similarity is a critical aspect of natural language processing, as it evaluates the degree of similarity within a knowledge graph. Various…”
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Subgraph-based feature fusion models for semantic similarity computation in heterogeneous knowledge graphs
Published in Knowledge-based systems (05-12-2022)“…Semantic similarity is a fundamental task in natural language processing that determines the similarity between two concepts within a taxonomy. For example, a…”
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Knowledge-Associated Embedding for Memory-Aware Knowledge Tracing
Published in IEEE transactions on computational social systems (01-06-2024)“…Knowledge tracing (KT) refers to predicting learners' performance in the future according to their historical learning interactions, which has become an…”
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The Ku70-SIX1-GPT2 axis regulates alpha-ketoglutarate metabolism to drive progression of prostate cancer
Published in Oncogene (02-11-2024)“…Sine oculis homeobox homolog 1 (SIX1) is a new identified cancer driver in the development of prostate cancer (PC). However, the upstream regulatory mechanisms…”
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A SIX1 degradation inducer blocks excessive proliferation of prostate cancer
Published in International journal of biological sciences (01-01-2022)“…Prostate cancer (PC) remains a great medical challenge due to its high incidence and the development of castration resistance in patients treated with androgen…”
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LXW7 attenuates inflammation via suppressing Akt/nuclear factor kappa B and mitogen-activated protein kinases signaling pathways in lipopolysaccharide-stimulated BV2 microglial cells
Published in International immunopharmacology (01-12-2019)“…•LXW7 inhibits microglia from releasing proinflammatory cytokines and mediators.•LXW7 modulates Akt/NF-κB and MARK signaling pathway activation.•LXW7 has…”
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TSPAN31 suppresses cell proliferation in human cervical cancer through down‐regulation of its antisense pairing with CDK4
Published in Cell biochemistry and function (01-07-2020)“…Natural antisense transcripts (NAT) are prevalent phenomena in the mammalian genome and play significant regulatory roles in gene expression. While new…”
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20
TSPAN 31 is a critical regulator on transduction of survival and apoptotic signals in hepatocellular carcinoma cells
Published in FEBS letters (01-09-2017)“…Tetraspanins are commonly believed to act as ‘molecular facilitators’, not directly involved in signal transduction. Tetraspanin 31 (TSPAN31), recently…”
Get full text
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