Search Results - "Deng, Yibin"
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Ultrastable Near‐Infrared Conjugated‐Polymer Nanoparticles for Dually Photoactive Tumor Inhibition
Published in Advanced materials (Weinheim) (01-08-2017)“…It is highly desired that satisfactory photoactive agents with ideal photophysical characteristics are explored for potent cancer phototherapeutics. Herein,…”
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Destruction of Full-Length Androgen Receptor by Wild-Type SPOP, but Not Prostate-Cancer-Associated Mutants
Published in Cell reports (Cambridge) (27-02-2014)“…The SPOP E3 ubiquitin ligase gene is frequently mutated in human prostate cancers. Here, we demonstrate that SPOP recognizes a Ser/Thr-rich degron in the hinge…”
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3
Size-Dependent Ag2S Nanodots for Second Near-Infrared Fluorescence/Photoacoustics Imaging and Simultaneous Photothermal Therapy
Published in ACS nano (28-02-2017)“…Ag2S nanoparticles are increasingly important in biomedicine, such as in cancer imaging. However, there has been only limited success in the exploration of…”
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Photoconversion‐Tunable Fluorophore Vesicles for Wavelength‐Dependent Photoinduced Cancer Therapy
Published in Advanced materials (Weinheim) (01-05-2017)“…Photoconversion tunability of fluorophore dye is of great interest in cancer nanomedicine such as fluorescence imaging, photodynamic therapy (PDT), and…”
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Bifunctional Tellurium Nanodots for Photo-Induced Synergistic Cancer Therapy
Published in ACS nano (24-10-2017)“…Elemental tellurium (Te) nanoparticles are increasingly important in a variety of applications such as thermoelectricity, photoconductivity, and…”
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Bifunctional Platinated Nanoparticles for Photoinduced Tumor Ablation
Published in Advanced materials (Weinheim) (01-12-2016)“…Bifunctional self‐assembled nanoparticles with a platinated fluorophore core with ultralow radiative transition are developed, which can generate both singlet…”
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7
Multiple roles for MRE11 at uncapped telomeres
Published in Nature (London) (13-08-2009)“…Progressive telomere attrition or uncapping of the shelterin complex elicits a DNA damage response as a result of a cell’s inability to distinguish…”
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8
Visualization of two architectures in class-II CAP-dependent transcription activation
Published in PLoS biology (20-04-2020)“…Transcription activation by cyclic AMP (cAMP) receptor protein (CAP) is the classic paradigm of transcription regulation in bacteria. CAP was suggested to…”
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Nanoparticle-mediated TRPV1 channel blockade amplifies cancer thermo-immunotherapy via heat shock factor 1 modulation
Published in Nature communications (29-04-2023)“…The survival of malignant tumors is highly dependent on their intrinsic self-defense pathways such as heat shock protein (HSP) during cancer therapy. However,…”
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Dually pH/Reduction-Responsive Vesicles for Ultrahigh-Contrast Fluorescence Imaging and Thermo-Chemotherapy-Synergized Tumor Ablation
Published in ACS nano (25-08-2015)“…Smart nanocarriers are of particular interest as nanoscale vehicles of imaging and therapeutic agents in the field of theranostics. Herein, we report dually…”
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Mutually Synergistic Nanoparticles for Effective Thermo‐Molecularly Targeted Therapy
Published in Advanced functional materials (19-10-2017)“…Photothermal therapy (PTT) is of particular importance as a highly potent therapeutic modality in cancer therapy. However, a critical challenge still remains…”
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Inhibition of miR‐148a‐3p resists hepatocellular carcinoma progress of hepatitis C virus infection through suppressing c‐Jun and MAPK pathway
Published in Journal of cellular and molecular medicine (01-02-2019)“…Objectives The present study was committed to investigate the role of miR‐148a‐3p in HCC infected with hepatitis C virus (HCV) and the regulatory mechanism of…”
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Hexokinase 2-Mediated Warburg Effect Is Required for PTEN- and p53-Deficiency-Driven Prostate Cancer Growth
Published in Cell reports (Cambridge) (11-09-2014)“…Accumulating evidence suggests that codeletion of the tumor suppressor genes Pten and p53 plays a crucial role in the development of castration-resistant…”
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14
Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth
Published in Cancer cell international (16-02-2016)“…The most common genetic changes identified in human NSCLC are Kras mutations (10-30 %) and p53 mutation or loss (50-70 %). Moreover, NSCLC with mutations in…”
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Role of telomeres and telomerase in genomic instability, senescence and cancer
Published in Laboratory investigation (01-11-2007)“…Telomeres are ribonucleoprotein structures that protect the end of linear chromosomes from recognition as DNA double-stranded breaks and activation of a DNA…”
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Displacement Values Calculation Method for Ship Multi-Support Shafting Based on Transfer Learning
Published in Journal of marine science and engineering (01-01-2024)“…Deviations between the design and actual shafting occur due to limitations in ship construction accuracy. Consequently, accurately obtaining the relationship…”
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TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
Published in Genes & development (01-01-2002)“…Recent reports suggest that a cross-talk exists between apoptosis pathways mediated by mitochondria and cell death receptors. In the present study, we report…”
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Mre11 Nuclease Activity Has Essential Roles in DNA Repair and Genomic Stability Distinct from ATM Activation
Published in Cell (03-10-2008)“…The Mre11/Rad50/NBS1 (MRN) complex maintains genomic stability by bridging DNA ends and initiating DNA damage signaling through activation of the ATM kinase…”
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The Efficacy and Safety of 5-Aminolevulinic Acid Photodynamic Therapy for Lichen Sclerosus: A Meta Analysis
Published in Indian journal of dermatology (01-01-2023)“…Lichen sclerosus (LS) is a chronic inflammatory dermatosis that occurs mainly in the anogenital area and causes itching, soreness, atrophy and scarring, which…”
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Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis
Published in Journal of translational medicine (12-01-2024)“…Lung cancer is the most prevalent cancer worldwide, with non-small cell lung cancer (NSCLC) accounting for 85% of all cases. Circular RNAs(circRNA) play…”
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