Search Results - "Deng, Xiu ling"

Cardiac β‐adrenergic receptor activation mediates distinct and cell type‐dependent changes in the expression and distribution of connexin 43 by Zhang, Yi, Hou, Meng‐Chen, Li, Jing‐Jing, Qi, Ying, Zhang, Yu, She, Gang, Ren, Yu‐Jie, Wu, Wei, Pang, Zheng‐Da, Xie, Wenjun, Deng, Xiu‐Ling, Du, Xiao‐Jun

“…Activation of the sympatho‐β‐adrenergic receptors (β‐ARs) system is a hallmark of heart failure, leading to fibrosis and arrhythmias. Connexin 43 (Cx43) is the…”
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Rhodiola and salidroside in the treatment of metabolic disorders by Bai, Xiang-Li, Deng, Xiu-Ling, Wu, Guang-Jie, Li, Wen-Jing, Jin, Si

“…Over the past three decades, the knowledge gained about the mechanisms that underpin the potential use of Rhodiola in stress- and ageing-associated disorders…”
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Activation of Hippo signaling pathway mediates mitochondria dysfunction and dilated cardiomyopathy in mice by Wu, Wei, Ziemann, Mark, Huynh, Kevin, She, Gang, Pang, Zheng-Da, Zhang, Yi, Duong, Thy, Kiriazis, Helen, Pu, Tian-Tian, Bai, Ru-Yue, Li, Jing-Jing, Zhang, Yu, Chen, Ming-Xia, Sadoshima, Junichi, Deng, Xiu-Ling, Meikle, Peter J, Du, Xiao-Jun

“…Mitochondrial dysfunction facilitates heart failure development forming a therapeutic target, but the mechanism involved remains unclear. We studied whether…”
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Hippo pathway activation mediates chemotherapy-induced anti-cancer effect and cardiomyopathy through causing mitochondrial damage and dysfunction by She, Gang, Du, Jin-Chan, Wu, Wei, Pu, Tian-Tian, Zhang, Yu, Bai, Ru-Yue, Zhang, Yi, Pang, Zheng-Da, Wang, Hui-Fang, Ren, Yu-Jie, Sadoshima, Junichi, Deng, Xiu-Ling, Du, Xiao-Jun

“…Chemotherapy is a common clinical strategy for cancer treatment. However, the accompanied cardiomyopathy renders cancer patients under risk of another…”
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Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy by Ziemann, Mark, Wu, Wei, Deng, Xiu-Ling, Du, Xiao-Jun

“…Background: Mitochondrial dysfunction is implicated in the development of cardiomyopathy and heart failure. Transcription of mitochondrial DNA (mtDNA) encoded…”
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Effects of equol on multiple K+ channels stably expressed in HEK 293 cells by Deng, Xiu-Ling, Wang, Yan, Xiao, Guo-Sheng

“…The present study investigated the effects of equol on cardiovascular K+ channel currents. The cardiovascular K+ channel currents were determined in HEK 293…”
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K Ca 3.1 Channels Promote Cardiac Fibrosis Through Mediating Inflammation and Differentiation of Monocytes Into Myofibroblasts in Angiotensin II -Treated Rats by She, Gang, Ren, Yu-Jie, Wang, Yan, Hou, Meng-Chen, Wang, Hui-Fang, Gou, Wei, Lai, Bao-Chang, Lei, Ting, Du, Xiao-Jun, Deng, Xiu-Ling

“…Background Cardiac fibrosis is a core pathological process associated with heart failure. The recruitment and differentiation of primitive fibroblast precursor…”
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KCa3.1 channel mediates inflammatory signaling of pancreatic β cells and progression of type 2 diabetes mellitus by Pang, Zheng‐Da, Wang, Yan, Wang, Xiao‐Jing, She, Gang, Ma, Xiao‐Zhen, Song, Zheng, Zhao, Li‐Mei, Wang, Hui‐Fang, Lai, Bao‐Chang, Gou, Wei, Du, Xiao‐Jun, Deng, Xiu‐Ling

“…Chronic islet inflammation is associated with development of type 2 diabetes mellitus (T2DM). Intermediate‐conductance calcium‐activated K+ (KCa3.1) channel…”
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Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts by Zhang, Yu, Li, Jing-Jing, Xu, Rui, Wang, Xin-Pei, Zhao, Xin-Yi, Fang, Yuan, Chen, Yu-Peng, Ma, Shan, Di, Xiao-Hui, Wu, Wei, She, Gang, Pang, Zheng-Da, Wang, Yi-Dong, Zhang, Xing, Xie, Wenjun, Deng, Xiu-Ling, Du, Xiao-Jun, Zhang, Yi

“…Endothelial dysfunction plays a pivotal role in atherosclerosis, but the detailed mechanism remains incomplete understood. Nogo-B is an endoplasmic reticulum…”
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Liraglutide protects β-cell function by reversing histone modification of Pdx-1 proximal promoter in catch-up growth male rats by Gao, Ming, Deng, Xiu-Ling, Liu, Zhen-Hua, Song, Hui-Jie, Zheng, Juan, Cui, Zhen-Hai, Xiao, Kang-Li, Chen, Lu-Lu, Li, Hui-Qing

“…Catch-up growth after a period of nutritional deprivation in adulthood is related to the onset of metabolic disorders. This process involves chromatin…”
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Cholesterol down-regulates BK channels stably expressed in HEK 293 cells by Wu, Wei, Wang, Yan, Deng, Xiu-Ling, Sun, Hai-Ying, Li, Gui-Rong

“…Cholesterol is one of the major lipid components of the plasma membrane in mammalian cells and is involved in the regulation of a number of ion channels. The…”
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AGEs-RAGE-KCa3.1 pathway mediates palmitic acid-induced migration of PBMCs from patients with type 2 diabetes by Zhang, Yi, Ma, Xiao-Zhen, Zhao, Xin-Yi, Li, Jing-Jing, Ma, Shan, Pang, Zheng-Da, Xu, Jing, Du, Xiao-Jun, Deng, Xiu-Ling, Wang, Jun-Hong

“…Type 2 diabetes mellitus (T2DM) is characterized by chronic low-grade systemic inflammation. Tissue infiltration by monocyte migration contributes to the…”
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Pathogenetic Link of Cardiac Rupture and Left Ventricular Thrombus Following Acute Myocardial Infarction: A Joint Preclinical and Clinical Study by Ma, Shan, Bai, Ling, Liu, Ping, She, Gang, Deng, Xiu-Ling, Song, An-Qi, Du, Xiao-Jun, Lu, Qun

“…BackgroundCardiac rupture (CR) and left ventricular thrombus (LVT) remain important complications of acute myocardial infarction (MI), and they are currently…”
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Indoor renovation and diabetes mellitus: Evidence from a cohort study by Zhang, Nan, Hu, Xiang, Zeng, Tian Shu, Zhang, Jiao‐Yue, Tian, Sheng‐Hua, Min, Jie, Huang, Han‐Tao, Zheng, Juan, Deng, Xiu‐Ling, Chen, Lu‐Lu

“…Highlights Household or workplace renovations increase 2hPG levels and diabetes risk Stratified analysis by age, gender, BMI, and hypertension showed that the…”
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Ion Channels in Mesenchymal Stem Cells from Rat Bone Marrow by Li, Gui‐Rong, Deng, Xiu‐Ling, Sun, Haiying, Chung, Stephen S.M., Tse, Hung‐Fat, Lau, Chu‐Pak

“…Mesenchymal stem cells (MSCs) from bone marrow are believed to be an ideal cell source for cardiomyoplasty; however, cellular electrophysiology is not…”
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Downregulation of human Wnt3 in gastric cancer suppresses cell proliferation and induces apoptosis by Wang, Hai-Sheng, Nie, Xiaobo, Wu, Rui-Bing, Yuan, Hong-Wei, Ma, Yue-Hong, Liu, Xiu-Lan, Zhang, Jian-Yu, Deng, Xiu-Ling, Na, Qin, Jin, Hai-Yan, Bian, Yan-Chao, Gao, Yu-Min, Wang, Yan-Dong, Chen, Wei-Dong

“…Aberrant activation of Wnt/β-catenin signaling pathways is closely involved in the occurrence and progression of several types of human malignancies. However,…”
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KCa3.1 Channels Promote Cardiac Fibrosis Through Mediating Inflammation and Differentiation of Monocytes Into Myofibroblasts in Angiotensin II–Treated Rats by She, Gang, Ren, Yu‐Jie, Wang, Yan, Hou, Meng‐Chen, Wang, Hui‐Fang, Gou, Wei, Lai, Bao‐Chang, Lei, Ting, Du, Xiao‐Jun, Deng, Xiu‐Ling

“…Background Cardiac fibrosis is a core pathological process associated with heart failure. The recruitment and differentiation of primitive fibroblast precursor…”
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Stretch-induced sarcoplasmic reticulum calcium leak is causatively associated with atrial fibrillation in pressure-overloaded hearts by Zhang, Yi, Qi, Ying, Li, Jing-Jing, He, Wen-Jin, Gao, Xiao-Hang, Zhang, Yu, Sun, Xia, Tong, Jie, Zhang, Jianbao, Deng, Xiu-Ling, Du, Xiao-Jun, Xie, Wenjun

“…Abstract Aims Despite numerous reports documenting an important role of hypertension in the development of atrial fibrillation (AF), the detailed mechanism…”
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Integrative analysis of the molecular signature of target genes involved in the antitumor effects of cantharidin on hepatocellular carcinoma by Yan, Jia, Gao, Yu min, Deng, Xiu ling, Wang, Hai sheng, Shi, Gui tao

“…Background Cantharidin (CTD) is the active ingredient of Chinese medicine, which has been traditionally used in multiple cancers treatment, especially in…”
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Evaluation of Coenzyme Q10 (CoQ10) Deficiency and Therapy in Mouse Models of Cardiomyopathy by Pu, Tian-Tian, Wu, Wei, Liang, Pei-Da, Du, Jin-Chan, Han, Sheng-Li, Deng, Xiu-Ling, Du, Xiao-Jun

“…Mitochondrial dysfunction plays a key role in the development of heart failure, but targeted therapeutic interventions remain elusive. Previous studies have…”
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