Search Results - "Deng, Wanyin"
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A rare case of an esophageal mass with varices: esophageal metastasis of hepatocellular carcinoma
Published in The American journal of gastroenterology (01-08-2023)Get full text
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Quantitative proteomic screen identifies annexin A2 as a host target for Salmonella pathogenicity island-2 effectors SopD2 and PipB2
Published in Scientific reports (08-12-2021)“…Intracellular pathogens need to establish an intracellular replicative niche to promote survival and replication within the hostile environment inside the host…”
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Both pathogen and host dynamically adapt pH responses along the intestinal tract during enteric bacterial infection
Published in PLoS biology (15-08-2024)“…Enteric pathogens navigate distinct regional microenvironments within the intestine that cue important adaptive behaviors. We investigated the response of…”
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Role of Inflammasomes in Host Defense against Citrobacter rodentium Infection
Published in The Journal of biological chemistry (11-05-2012)“…Citrobacter rodentium is an enteric bacterial pathogen of the mouse intestinal tract that triggers inflammatory responses resembling those of humans infected…”
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GrlR, a negative regulator in enteropathogenic E. coli , also represses the expression of LEE virulence genes independently of its interaction with its cognate partner GrlA
Published in Frontiers in microbiology (16-02-2023)“…Enteropathogenic (EPEC), enterohemorrhagic (EHEC) and (CR) belong to a group of pathogens that share the ability to form "attaching and effacing" (A/E) lesions…”
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Quantitative Proteomic Analysis of Type III Secretome of Enteropathogenic Escherichia coli Reveals an Expanded Effector Repertoire for Attaching/Effacing Bacterial Pathogens
Published in Molecular & cellular proteomics (01-09-2012)“…Type III secretion systems are central to the pathogenesis and virulence of many important Gram-negative bacterial pathogens, and elucidation of the secretion…”
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A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system
Published in Nature structural & molecular biology (01-05-2009)“…The type III secretion system (T3SS) of pathogenic bacteria is composed of a series of rings in the inner and outer bacterial membranes. Crystallographic…”
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Quorum sensing modulates bacterial virulence and colonization dynamics of the gastrointestinal pathogen Citrobacter rodentium
Published in Gut microbes (18-12-2023)“…Quorum Sensing (QS) is a form of cell-to-cell communication that enables bacteria to modify behavior according to their population density. While QS has been…”
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Attaching and Effacing Bacterial Effector NleC Suppresses Epithelial Inflammatory Responses by Inhibiting NF-κB and p38 Mitogen-Activated Protein Kinase Activation
Published in Infection and Immunity (01-09-2011)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly
Published in Nature microbiology (01-11-2019)“…The bacterial injectisome is a syringe-shaped macromolecular nanomachine utilized by many pathogenic Gram-negative bacteria, including the causative agents of…”
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EscI: a crucial component of the type III secretion system forms the inner rod structure in enteropathogenic Escherichia coli
Published in Biochemical journal (15-02-2012)“…The T3SS (type III secretion system) is a multi-protein complex that plays a central role in the virulence of many gram-negative bacterial pathogens. This…”
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Simultaneous Recognition of Atrophic Gastritis and Intestinal Metaplasia on White Light Endoscopic Images Based on Convolutional Neural Networks: A Multicenter Study
Published in Clinical and translational gastroenterology (03-08-2021)“…Patients with atrophic gastritis (AG) or gastric intestinal metaplasia (GIM) have elevated risk of gastric adenocarcinoma. Endoscopic screening and…”
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Dissecting Virulence: Systematic and Functional Analyses of a Pathogenicity Island
Published in Proceedings of the National Academy of Sciences - PNAS (09-03-2004)“…Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host…”
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Structural analysis of a prototypical ATPase from the type III secretion system
Published in Nature structural & molecular biology (01-02-2007)“…The type III secretion system (T3SS) ATPase is the conserved and essential inner-membrane component involved in the initial stages of selective secretion of…”
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A Novel Subcellular Machine Contributes to Basal Junction Remodeling in the Seminiferous Epithelium
Published in Biology of reproduction (01-03-2013)“…Tubulobulbar complexes are cytoskeleton-related membrane structures that develop at sites of intercellular attachment in mammalian seminiferous epithelium. At…”
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Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS
Published in Nature (01-05-2008)“…During infection by Gram-negative pathogenic bacteria, the type III secretion system (T3SS) is assembled to allow for the direct transmission of bacterial…”
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Quantitative Proteomic Analysis Reveals Formation of an EscL-EscQ-EscN Type III Complex in Enteropathogenic Escherichia coli
Published in Journal of Bacteriology (01-10-2011)“…We characterized Orf5 and SepQ, two type III secretion (T3S) system proteins in enteropathogenic Escherichia coli, and showed that they are essential for T3S,…”
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A Comprehensive Proteomic Analysis of the Type III Secretome of Citrobacter rodentium
Published in The Journal of biological chemistry (26-02-2010)“…Enteropathogenic Escherichia coli, enterohemorrhagic E. coli, and Citrobacter rodentium belong to the family of attaching and effacing (A/E) bacterial…”
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The Type III System-Secreted Effector EspZ Localizes to Host Mitochondria and Interacts with the Translocase of Inner Mitochondrial Membrane 17b
Published in Infection and Immunity (01-12-2011)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Attaching and effacing pathogen‐induced tight junction disruption in vivo
Published in Cellular microbiology (01-04-2006)“…Summary Diarrhoea is a hallmark of infections by the human attaching and effacing (A/E) pathogens, enterohaemorrhagic Escherichia coli (EHEC) and…”
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