Search Results - "Deng, Sophie X."

The application of human amniotic membrane in the surgical management of limbal stem cell deficiency by Le, Qihua, Deng, Sophie X.

“…The application of human amniotic membrane (AM) has a wide spectrum of indications in the treatment of ocular surface disorders. Transplantation of AM has been…”
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Global Consensus on Definition, Classification, Diagnosis, and Staging of Limbal Stem Cell Deficiency by Deng, Sophie X, Borderie, Vincent, Chan, Clara C, Dana, Reza, Figueiredo, Francisco C, Gomes, José A P, Pellegrini, Graziella, Shimmura, Shigeto, Kruse, Friedrich E

“…PURPOSE:Despite extensive knowledge gained over the last 3 decades regarding limbal stem cell deficiency (LSCD), the disease is not clearly defined, and there…”
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Corneal Epithelial Thickness Measured Using Anterior Segment Optical Coherence Tomography as a Diagnostic Parameter for Limbal Stem Cell Deficiency by Liang, Qingfeng, Le, Qihua, Cordova, Daniel W., Tseng, Chi-Hong, Deng, Sophie X.

“…Using anterior segment optical coherence tomography (AS-OCT), we investigated the epithelial thickness (ET) of the central cornea and limbal regions in…”
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Mesenchymal Stem Cells Reduce Corneal Fibrosis and Inflammation via Extracellular Vesicle‐Mediated Delivery of miRNA by Shojaati, Golnar, Khandaker, Irona, Funderburgh, Martha L., Mann, Mary M., Basu, Rohan, Stolz, Donna B., Geary, Moira L., Dos Santos, Aurélie, Deng, Sophie X., Funderburgh, James L.

“…Mesenchymal stem cells from corneal stromal stem cells (CSSC) prevent fibrotic scarring and stimulate regeneration of transparent stromal tissue after corneal…”
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Global Consensus on the Management of Limbal Stem Cell Deficiency by Deng, Sophie X., Kruse, Friedrich, Gomes, José A. P., Chan, Clara C., Daya, Sheraz, Dana, Reza, Figueiredo, Francisco C., Kinoshita, Shigeru, Rama, Paolo, Sangwan, Virender, Slomovic, Allan R., Tan, Donald

“…PURPOSE:In recent decades, the medical and surgical treatment of limbal stem cell deficiency (LSCD) has evolved significantly through the incorporation of…”
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Assessment of corneal epithelial thickness in dry eye patients by Cui, Xinhan, Hong, Jiaxu, Wang, Fei, Deng, Sophie X, Yang, Yujing, Zhu, Xiaoyu, Wu, Dan, Zhao, Yujin, Xu, Jianjiang

“…To investigate the features of corneal epithelial thickness topography with Fourier-domain optical coherence tomography (OCT) in dry eye patients. In this…”
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Regulation of Limbal Epithelial Stem Cells: Importance of the Niche by Robertson, Sarah Y T, Roberts, JoAnn S, Deng, Sophie X

“…Limbal epithelial stem/progenitor cells (LSCs) reside in a niche that contains finely tuned balances of various signaling pathways including Wnt, Notch, BMP,…”
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Classification of Limbal Stem Cell Deficiency Using Clinical and Confocal Grading by Aravena, Carolina, Bozkurt, Kansu, Chuephanich, Pichaya, Supiyaphun, Chantaka, Yu, Fei, Deng, Sophie X

“…PURPOSE:To grade the severity of limbal stem cell deficiency (LSCD) based on the extent of clinical presentation and central corneal basal epithelial cell…”
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Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency by Bonnet, Clémence, González, Sheyla, Deng, Sophie X., Zheng, Jie J.

“…Limbal epithelial stem/progenitor cells (LSCs) are adult stem cells located at the limbus, tightly regulated by their niche involving numerous signaling…”
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Stability and Function of Extracellular Vesicles Derived from Immortalized Human Corneal Stromal Stem Cells: A Proof of Concept Study by Lyu, Ning, Knight, Robert, Robertson, Sarah Y. T., Dos Santos, Aurelie, Zhang, Chi, Ma, Chao, Xu, Jianjiang, Zheng, Jie, Deng, Sophie X.

“…With significant advancement and development of extracellular vesicle (EV)-based therapies, there is a growing need to understand how their storage affects…”
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Ultrastructure of the Posterior Corneal Stroma by Schlötzer-Schrehardt, Ursula, PhD, Bachmann, Bjoern O., MD, Tourtas, Theofilos, MD, Torricelli, Andre A.M., MD, Singh, Arun, MD, González, Sheyla, PhD, Mei, Hua, PhD, Deng, Sophie X., MD, PhD, Wilson, Steven E., MD, Kruse, Friedrich E., MD

“…Purpose To reinvestigate the ultrastructure of the posterior stroma of the human cornea and to correlate the findings with the stromal behavior after…”
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Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells by Bonnet, Clémence, Oh, Denise, Mei, Hua, Robertson, Sarah, Chang, Derek, Bourges, Jean-Louis, Behar-Cohen, Francine, Zheng, Jie J., Deng, Sophie X.

“…The corneal epithelium is consistently regenerated by limbal stem/progenitor cells (LSCs), a very small population of adult stem cells residing in the limbus…”
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Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells by Chen, Yinyin, Huang, Kevin, Nakatsu, Martin N, Xue, Zhigang, Deng, Sophie X, Fan, Guoping

“…The corneal endothelium is composed of a monolayer of corneal endothelial cells (CECs), which is essential for maintaining corneal transparency. To better…”
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Generation of Functional Immortalized Human Corneal Stromal Stem Cells by Dos Santos, Aurelie, Lyu, Ning, Balayan, Alis, Knight, Rob, Zhuo, Katherine Sun, Sun, Yuzhao, Xu, Jianjiang, Funderburgh, Martha L, Funderburgh, James L, Deng, Sophie X

“…In addition to their therapeutic potential in regenerative medicine, human corneal stromal stem cells (CSSCs) could serve as a powerful tool for drug discovery…”
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Expansion of Human Limbal Epithelial Stem/Progenitor Cells Using Different Human Sera: A Multivariate Statistical Analysis by Hernáez-Moya, Raquel, González, Sheyla, Urkaregi, Arantza, Pijoan, Jose Ignacio, Deng, Sophie X, Andollo, Noelia

“…Transplantation of human cultured limbal epithelial stem/progenitor cells (LESCs) has demonstrated to restore the integrity and functionality of the corneal…”
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THz and mm-Wave Sensing of Corneal Tissue Water Content: In Vivo Sensing and Imaging Results by Taylor, Zachary D., Garritano, James, Shijun Sung, Bajwa, Neha, Bennett, David B., Nowroozi, Bryan, Tewari, Priyamvada, Sayre, James W., Hubschman, Jean-Pierre, Deng, Sophie X., Brown, Elliott R., Grundfest, Warren S.

“…A pulsed terahertz (THz) imaging system and millimeter-wave reflectometer were used to acquire images and point measurements, respectively, of five rabbit…”
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Genome-wide analysis suggests a differential microRNA signature associated with normal and diabetic human corneal limbus by Kulkarni, Mangesh, Leszczynska, Aleksandra, Wei, Gabbie, Winkler, Michael A., Tang, Jie, Funari, Vincent A., Deng, Nan, Liu, Zhenqiu, Punj, Vasu, Deng, Sophie X., Ljubimov, Alexander V., Saghizadeh, Mehrnoosh

“…Small non-coding RNAs, in particular microRNAs (miRNAs), regulate fine-tuning of gene expression and can impact a wide range of biological processes. However,…”
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Human adipose-derived stem cells support the growth of limbal stem/progenitor cells by Mei, Hua, González, Sheyla, Nakatsu, Martin N, Baclagon, Elfren R, Chen, Felix V, Deng, Sophie X

“…The most efficient method to expand limbal stem cells (LSCs) in vitro for clinical transplantation is to culture single LSCs directly on growth-arrested mouse…”
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Corneal epithelial thickness map in long-term soft contact lenses wearers by Hong, Jiaxu, Qian, Tingting, Yang, Yujing, Jiang, Chunhui, Liu, Zuguo, Sun, Xinghuai, Deng, Sophie X, Xu, Jianjiang

“…To map the corneal epithelial thickness in vivo with Fourier-domain optical coherence tomography in long-term soft contact lens (SCL) wearers. This is a…”
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Submillimeter-wave cornea phantom sensing over an extended depth of field with an axicon-generated Bessel beam by Baggio, Mariangela, Tamminen, Aleksi, Lamberg, Joel, Grigorev, Roman, Palli, Samu-Ville, Ala-Laurinaho, Juha, Nefedova, Irina, Bourges, Jean-Louis, Deng, Sophie X., Brown, Elliott R., Wallace, Vincent P., Taylor, Zachary D.

“…The feasibility of a 220 - 330 GHz zero order axicon generated Bessel beam for corneal water content was explored. Simulation and experimental data from the…”
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