Search Results - "Deng, Senyi"

Artificial intelligence in cancer target identification and drug discovery by You, Yujie, Lai, Xin, Pan, Yi, Zheng, Huiru, Vera, Julio, Liu, Suran, Deng, Senyi, Zhang, Le

“…Artificial intelligence is an advanced method to identify novel anticancer targets and discover novel drugs from biology networks because the networks can…”
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A review of artificial intelligence applications for antimicrobial resistance by Lv, Ji, Deng, Senyi, Zhang, Le

“…The wide use and abuse of antibiotics could make antimicrobial resistance (AMR) an increasingly serious issue that threatens global health and imposes an…”
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Cationic nanocarriers induce cell necrosis through impairment of Na^＋/K^＋-ATPase and cause subsequent inflammatory response by Wei, Xiawei, Shao, Bin, He, Zhiyao, Ye, Tinghong, Luo, Min, Sang, Yaxiong, Liang, Xiao, Wang, Wei, Luo, Shuntao, Yang, Shengyong, Zhang, Shuang, Gong, Changyang, Gou, Maling, Deng, Hongxing, Zhao, Yinglan, Yang, Hanshuo, Deng, Senyi, Zhao, Chengjian, Yang, Li, Qian, Zhiyong, Li, Jiong, Sun, Xun, Han, Jiahuai, Jiang, Chengyu, Wu, Min, Zhang, Zhirong

“…Nanocarriers with positive surface charges are known for their toxicity which has limited their clinical appli- cations. The mechanism underlying their…”
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Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles by Gong, Changyang, Deng, Senyi, Wu, Qinjie, Xiang, Mingli, Wei, Xiawei, Li, Ling, Gao, Xiang, Wang, Bilan, Sun, Lu, Chen, Yishan, Li, Yuchen, Liu, Lei, Qian, Zhiyong, Wei, Yuquan

“…Abstract For developing aqueous formulation and improving anti-tumor activity of curcumin (Cur), we prepared Cur encapsulated MPEG-PCL micelles by solid…”
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Predictive value of pretreatment PD-L1 expression in EGFR-mutant non-small cell lung cancer: a meta-analysis by Peng, Zhiyu, Lin, Huahang, Zhou, Ke, Deng, Senyi, Mei, Jiandong

“…To investigate the predictive value of programmed death-ligand 1 (PD-L1) expression in non-small cell lung cancer (NSCLC) patients treated with epidermal…”
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Ectopic bronchogenic cyst arising from the diaphragm: a rare case report and literature review by Tang, Juan, Zeng, Zhen, Deng, Senyi, Lin, Feng

“…Abstract Background Bronchogenic cysts can be caused by errors in the growth of the ventral foregut. Localization of the bronchogenic cyst (BC) varies…”
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Targeting cancer-related inflammation with non-steroidal anti-inflammatory drugs: Perspectives in pharmacogenomics by Lai, Hongjin, Liu, Yi, Wu, Juan, Cai, Jie, Jie, Hui, Xu, Yuyang, Deng, Senyi

“…Inflammatory processes are essential for innate immunity and contribute to carcinogenesis in various malignancies, such as colorectal cancer, esophageal cancer…”
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A Novel Immune-Prognosis Index Predicts the Benefit of Lung Adenocarcinoma Patients by Bai, Yuquan, Pei, Yun, Xia, Liang, Ma, Lin, Deng, Senyi

“…Constructed an immune-prognosis index (IPI) and divided lung adenocarcinoma (LUAD) patients into different subgroups according to IPI score, describe the…”
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Extensive infiltration of CD8+ T cells and M1 macrophages is beneficial for multiple cancer patients undergoing chemotherapy by Bai, Yuquan, Xu, He, Guo, Minzhang, Xia, Liang, Deng, Senyi

“…Not all patients can benefit from chemotherapy due to the various of tumor type, stage, location, and the different distribution of immune cells in tumor…”
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Effect of a genetically engineered interferon-alpha versus traditional interferon-alpha in the treatment of moderate-to-severe COVID-19: a randomised clinical trial by Li, Chuan, Luo, Fengming, Liu, Chengwu, Xiong, Nian, Xu, Zhihua, Zhang, Wei, Yang, Ming, Wang, Ye, Liu, Dan, Yu, Chao, Zeng, Jia, Zhang, Li, Li, Duo, Liu, Yanbin, Feng, Mei, Liu, Ruoyang, Mei, Jiandong, Deng, Senyi, Zeng, Zhen, He, Yuanhong, Liu, Haiyan, Shi, Zhengyu, Duan, Meng, Kang, Deying, Liao, Jiayu, Li, Weimin, Liu, Lunxu

“…There are few effective therapies for coronavirus disease 2019 (COVID-19) upon the outbreak of the pandemic. To compare the effectiveness of a novel…”
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Metformin attenuates chronic lung allograft dysfunction: evidence in rat models by Tian, Dong, Zheng, Xiangyun, Tang, Hongtao, Huang, Heng, Wang, Junjie, Xu, Lin, Li, Caihan, Yan, Haoji, Yu, Ruixuan, Nan, Jinzhu, Liu, Menggen, Guo, Xiaoguang, Jian, Shunhai, Wang, Tao, Deng, Senyi, Pu, Qiang, Liu, Lunxu

“…Chronic lung allograft dysfunction (CLAD) directly causes an abysmal long-term prognosis after lung transplantation (LTx), but effective and safe drugs are not…”
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Non-coding RNA and its network in the pathogenesis of Myasthenia Gravis by Wang, Fuqiang, Mei, Xiaoli, Yang, Yunhao, Zhang, Hanlu, Li, Zhiyang, Zhu, Lei, Deng, Senyi, Wang, Yun

“…Myasthenia Gravis (MG) is a chronic autoimmune disease that primarily affects the neuromuscular junction, leading to muscle weakness in patients with this…”
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SKLB1002, a Novel Potent Inhibitor of VEGF Receptor 2 Signaling, Inhibits Angiogenesis and Tumor Growth In Vivo by Zhang, Shuang, Cao, Zhixing, Tian, Hongwei, Shen, Guobo, Ma, Yongping, Xie, Huanzhang, Liu, Yalin, Zhao, Chengjian, Deng, Senyi, Yang, Yang, Zheng, Renlin, Li, Weiwei, Zhang, Na, Liu, Shengyong, Wang, Wei, Dai, Lixia, Shi, Shuai, Cheng, Lin, Pan, Youli, Feng, Shan, Zhao, Xia, Deng, Hongxin, Yang, Shengyong, Wei, Yuquan

“…VEGF receptor 2 (VEGFR2) inhibitors, as efficient antiangiogenesis agents, have been applied in the cancer treatment. However, currently most of these…”
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Tet methylcytosine dioxygenase 2 (TET2) deficiency elicits EGFR-TKI (tyrosine kinase inhibitors) resistance in non-small cell lung cancer by Zhang, Jian, Zhao, Kejia, Zhou, Wenjing, Kang, Ran, Wei, Shiyou, Shu, Yueli, Yu, Cheng, Ku, Yin, Mao, Yonghong, Luo, Hao, Yang, Juqin, Mei, Jiandong, Pu, Qiang, Deng, Senyi, Zha, Zhengyu, Yuan, Gang, Shen, Shensi, Chen, Yaohui, Liu, Lunxu

“…Despite epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) have shown remarkable efficacy in patients with EGFR -mutant non-small cell…”
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A six-long noncoding RNA model predicts prognosis in lung adenocarcinoma by Bai, Yuquan, Deng, Senyi

“…The incidence and mortality of lung cancer rank first among various malignant tumors. The lack of clear molecular classification and effective individualized…”
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Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer by Bai, Yuquan, Zhou, Lu, Zhang, Chuanfen, Guo, Minzhang, Xia, Liang, Tang, Zhenying, Liu, Yi, Deng, Senyi

“…The drug therapy for non-small cell lung cancer (NSCLC) have always been issues of poisonous side effect, acquired drug resistance and narrow applicable…”
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Perioperative ctDNA-Based Molecular Residual Disease Detection for Non-Small Cell Lung Cancer: A Prospective Multicenter Cohort Study (LUNGCA-1) by Xia, Liang, Mei, Jiandong, Kang, Ran, Deng, Senyi, Chen, Yaohui, Yang, Ying, Feng, Gang, Deng, Yulan, Gan, Fanyi, Lin, Yidan, Pu, Qiang, Ma, Lin, Lin, Feng, Yuan, Yong, Hu, Yang, Guo, Chenglin, Liao, Hu, Liu, Chengwu, Zhu, Yunke, Wang, Wenping, Liu, Zheng, Xu, Yuyang, Li, Kaidi, Li, Chuan, Li, Qingyun, He, Ji, Chen, Weizhi, Zhang, Xiaolong, Kou, Yingli, Wang, Yun, Wu, Zhu, Che, Guowei, Chen, Longqi, Liu, Lunxu

“…We assessed whether perioperative circulating tumor DNA (ctDNA) could be a biomarker for early detection of molecular residual disease (MRD) and prediction of…”
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Association between postoperative radiotherapy for young-onset nonsmall cell lung cancer and risk of second primary malignancies: comparative study by Li, Zuwei, Guo, Minzhang, Liu, Lunxu, Deng, Senyi

“…The most common form of therapy for nonsmall cell lung cancer (NSCLC) in early stage is surgery-based combination therapy, including radiotherapy and…”
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Association between postoperative radiotherapy for young-onset non–small cell lung cancer and risk of second primary malignancies ----Comparative study by Li, Zuwei, Guo, Minzhang, Liu, Lunxu, Deng, Senyi

“…Background: The most common form of therapy for non–small cell lung cancer (NSCLC) in early stage is surgery-based combination therapy, including radiotherapy…”
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Tumor-endogenous PD-1 promotes cell proliferation and predicts poor survival in non-small cell lung cancer by Gan, Fanyi, Zhang, Chuanfen, Xia, Liang, Deng, Senyi

“…Immunotherapy has emerged as a promising treatment strategy in malignant tumors. Inhibitors and neutralizing antibodies targeted PD-1 or PD-L1 show improved…”
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