Search Results - "Deng, Meichun"

Roles of Phosphorylation of N-Methyl-d-Aspartate Receptor in Chronic Pain by Pan, Liangyu, Li, Tiansheng, Wang, Rui, Deng, Weiheng, Pu, Huangsheng, Deng, Meichun

“…Phosphorylation of N-methyl- d -aspartate receptor (NMDAR) is widely regarded as a vital modification of synaptic function. Various protein kinases are…”
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Structure and Function of Sodium Channel Nav1.3 in Neurological Disorders by Liao, Sheng, Liu, Tao, Yang, Ruozhu, Tan, Weitong, Gu, Jiaqi, Deng, Meichun

“…Nav1.3, encoded by the SCN3A gene, is a voltage-gated sodium channel on the cell membrane. It is expressed abundantly in the fetal brain but little in the…”
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A Novel Peptide from Polypedates megacephalus Promotes Wound Healing in Mice by Fu, Siqi, Du, Canwei, Zhang, Qijian, Liu, Jiayu, Zhang, Xushuang, Deng, Meichun

“…Amphibian skin contains wound-healing peptides, antimicrobial peptides, and insulin-releasing peptides, which give their skin a strong regeneration ability to…”
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The Functional Role of Voltage-Gated Sodium Channel Nav1.5 in Metastatic Breast Cancer by Luo, Qianxuan, Wu, Ting, Wu, Wenfang, Chen, Gong, Luo, Xuan, Jiang, Liping, Tao, Huai, Rong, Mingqiang, Kang, Shuntong, Deng, Meichun

“…Voltage-gated sodium channels (VGSCs), which are abnormally expressed in various types of cancers such as breast cancer, prostate cancer, lung cancer, and…”
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Protein Kinase C-Mediated Phosphorylation and α2δ-1 Interdependently Regulate NMDA Receptor Trafficking and Activity by Zhou, Meng-Hua, Chen, Shao-Rui, Wang, Li, Huang, Yuying, Deng, Meichun, Zhang, Jixiang, Zhang, Jiyuan, Chen, Hong, Yan, Jiusheng, Pan, Hui-Lin

“…-methyl-d-aspartate receptors (NMDARs) are important for synaptic plasticity associated with many physiological functions and neurologic disorders. Protein…”
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Spider venom peptides as potential drug candidates due to their anticancer and antinociceptive activities by Wu, Ting, Wang, Meng, Wu, Wenfang, Luo, Qianxuan, Jiang, Liping, Tao, Huai, Deng, Meichun

“…Spider venoms are known to contain proteins and polypeptides that perform various functions including antimicrobial, neurotoxic, analgesic, cytotoxic,…”
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Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels by Wu, Wenfang, Yin, Yuan, Feng, Peihao, Chen, Gong, Pan, Liangyu, Gu, Panyang, Zhou, Siqin, Lin, Fulong, Ji, Siyu, Zheng, Chunbing, Deng, Meichun

“…Nav1.5 channel is crucial for the proliferation and migration of breast cancer cells. In this study, we investigated the anticancer effect of JZTX-14, a…”
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Modalities and Mechanisms of Treatment for Coronavirus Disease 2019 by Zuo, Zhihong, Wu, Ting, Pan, Liangyu, Zuo, Chenzhe, Hu, Yingchuo, Luo, Xuan, Jiang, Liping, Xia, Zanxian, Xiao, Xiaojuan, Liu, Jing, Ye, Mao, Deng, Meichun

“…Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading rapidly throughout the…”
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Jingzhaotoxin-X, a gating modifier of Kv4.2 and Kv4.3 potassium channels purified from the venom of the Chinese tarantula Chilobrachys jingzhao by Deng, Meichun, Jiang, Liping, Luo, Xuan, Tao, Huai, Liang, Songping

“…The tarantula is one of the largest venomous spiders in China. In previous studies, we purified and characterized at least eight peptides from venom. In this…”
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Anti- Toxoplasma gondii Effects of a Novel Spider Peptide XYP1 In Vitro and In Vivo by Liu, Yuan, Tang, Yaqin, Tang, Xing, Wu, Mengqi, Hou, Shengjie, Liu, Xiaohua, Li, Jing, Deng, Meichun, Huang, Shuaiqin, Jiang, Liping

“…Toxoplasmosis, caused by an obligate intracellular parasite , is one of the most prevalent zoonoses worldwide. Treatments for this disease by traditional drugs…”
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Interaction site for the inhibition of tarantula Jingzhaotoxin-XI on voltage-gated potassium channel Kv2.1 by Tao, Huai, Chen, Xia, Deng, Meichun, Xiao, Yucheng, Wu, Yuanyuan, Liu, Zhonghua, Zhou, Sainan, He, Yingchun, Liang, Songping

“…Jingzhaotoxin-XI (JZTX-XI) is a 34-residue peptide from the Chinese tarantula Chilobrachys jingzhao venom that potently inhibits both voltage-gated sodium…”
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Original Hosts, Clinical Features, Transmission Routes, and Vaccine Development for Coronavirus Disease (COVID-19) by Wu, Ting, Kang, Shuntong, Peng, Wenyao, Zuo, Chenzhe, Zhu, Yuhao, Pan, Liangyu, Fu, Keyun, You, Yaxian, Yang, Xinyuan, Luo, Xuan, Jiang, Liping, Deng, Meichun

“…The pandemic of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to public concern…”
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Correction: Liu et al. Anti- Toxoplasma gondii Effects of a Novel Spider Peptide XYP1 In Vitro and In Vivo. Biomedicines 2021, 9 , 934 by Liu, Yuan, Tang, Yaqin, Tang, Xing, Wu, Mengqi, Hou, Shengjie, Liu, Xiaohua, Li, Jing, Deng, Meichun, Huang, Shuaiqin, Jiang, Liping

“…In the original publication, there were mistakes in Figure 3C, Figure 6B and Figure S2A,B as published [...]…”
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Drosotoxin, a selective inhibitor of tetrodotoxin-resistant sodium channels by Zhu, Shunyi, Gao, Bin, Deng, Meichun, Yuan, Yuzhe, Luo, Lan, Peigneur, Steve, Xiao, Yucheng, Liang, Songping, Tytgat, Jan

“…The design of animal toxins with high target selectivity has long been a goal in protein engineering. Based on evolutionary relationship between the Drosophila…”
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Solution Structure and Functional Characterization of Jingzhaotoxin-XI:  A Novel Gating Modifier of both Potassium and Sodium Channels by Liao, Zhi, Yuan, Chunhua, Deng, Meichun, Li, Jiang, Chen, Jinjun, Yang, Yuejun, Hu, Weijun, Liang, Songping

“…JZTX-XI is a peptide toxin isolated from the venom of the Chinese spider Chilobrachys jingzhao. It contains 34 residues including six cysteine residues with…”
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Isolation and characterization of Jingzhaotoxin-V, a novel neurotoxin from the venom of the spider Chilobrachys jingzhao by Zeng, Xiongzhi, Deng, Meichun, Lin, Ying, Yuan, Chunhua, Pi, Jianhui, Liang, Songping

“…Jingzhaotoxin-V (JZTX-V), a 29-residue polypeptide, is derived from the venom of the spider Chilobrachys jingzhao. Its cDNA determined by rapid amplification…”
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Inhibition of insect calcium channels by huwentoxin-V, a neurotoxin from Chinese tarantula Ornithoctonus huwena venom by Deng, Meichun, Luo, Xuan, Meng, Er, Xiao, Yucheng, Liang, Songping

“…The effects of huwentoxin-V, an insect neurotoxic peptide from Chinese tarantula Ornithoctonus huwena venom, were studied on neuronal voltage-gated ion…”
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Synthesis and characterization of huwentoxin-IV, a neurotoxin inhibiting central neuronal sodium channels by Xiao, Yucheng, Luo, Xuan, Kuang, Fang, Deng, Meichun, Wang, Meichi, Zeng, Xiongzhi, Liang, Songping

“…Our previous work demonstrated that huwentoxin-IV was an inhibitor cystine knot peptide from Chinese tarantula Ornithoctonus huwena venom that blocked…”
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Function and Solution Structure of Huwentoxin-X, a Specific Blocker of N-type Calcium Channels, from the Chinese Bird Spider Ornithoctonus huwena by Liu, Zhonghua, Dai, Jie, Dai, Longjun, Deng, Meichun, Hu, Zhe, Hu, Weijun, Liang, Songping

“…Huwentoxin-X (HWTX-X) is a novel peptide toxin, purified from the venom of the spider Ornithoctonus huwena. It comprises 28 amino acid residues including six…”
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New advances in Nrf2-mediated analgesic drugs by Luan, Yifan, Luo, Yaping, Deng, Meichun

“…Oxidative stress is an inevitable process that occurs during life activities, and it can participate in the development of inflammation. Although great…”
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