Search Results - "Deng, Junpeng"

Structural biology of the IL‐1 superfamily: Key cytokines in the regulation of immune and inflammatory responses by Krumm, Brian, Xiang, Yan, Deng, Junpeng

“…Interleukin‐1 superfamily of cytokines (IL‐1, IL‐18, IL‐33) play key roles in inflammation and regulating immunity. The mechanisms of agonism and antagonism in…”
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Crystal structure of Manduca sexta prophenoloxidase provides insights into the mechanism of type 3 copper enzymes by Li, Yongchao, Wang, Yang, Jiang, Haobo, Deng, Junpeng

“…Arthropod phenoloxidase (PO) generates quinones and other toxic compounds to sequester and kill pathogens during innate immune responses. It is also involved…”
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Identification of PANoptosis-related signature reveals immune infiltration characteristics and immunotherapy responses for renal cell carcinoma by Xu, Yan, Hua, Jingqi, Que, Hongliang, Zeng, Tengyue, Li, Quan, Deng, Junpeng, Xie, Jianjun

“…PANoptosis is a specific type of inflammatory programmed cell death (PCD) modality that can be involved in three key modes of cellular programmed cell…”
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Evaluation of prostate cancer antigen 3 for detecting prostate cancer: a systematic review and meta-analysis by Cui, Yong, Cao, Wenzhou, Li, Quan, Shen, Hua, Liu, Chao, Deng, Junpeng, Xu, Jiangfeng, Shao, Qiang

“…Previous studies indicate that prostate cancer antigen 3 (PCA3) is highly expressed in prostatic tumors. However, its clinical value has not been…”
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Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor by Khandelwal, Anuj, Kent, Caitlin N., Balch, Maurie, Peng, Shuxia, Mishra, Sanket J., Deng, Junpeng, Day, Victor W., Liu, Weiya, Subramanian, Chitra, Cohen, Mark, Holzbeierlein, Jeffery M., Matts, Robert, Blagg, Brian S. J.

“…The 90 kDa heat shock protein (Hsp90) is a molecular chaperone responsible for folding proteins that are directly associated with cancer progression…”
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A review of system topologies, key operation and control technologies for offshore wind power transmission based on HVDC by Deng, Junpeng, Cheng, Fan, Yao, Liangzhong, Xu, Jian, Mao, Beilin, Li, Xianyu, Chen, Rusi

“…Offshore wind farm (OWF) is considered as a perfect zero‐carbon energy source for the future power system. However, the growing offshore distance and water…”
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Identification of small molecule inhibitors of Interleukin-18 by Krumm, Brian, Meng, Xiangzhi, Xiang, Yan, Deng, Junpeng

“…Interleukin-18 (IL-18) is a pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. IL-18 plays an important role in host innate and adaptive…”
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Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L by Peng, Shuxia, Meng, Xiangzhi, Zhang, Fushun, Pathak, Prabhat Kumar, Chaturvedi, Juhi, Coronado, Jaime, Morales, Marisol, Mao, Yuanhui, Qian, Shu-Bing, Deng, Junpeng, Xiang, Yan

“…SAMD9 and SAMD9L (SAMD9/9L) are antiviral factors and tumor suppressors, playing a critical role in innate immune defense against poxviruses and the…”
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Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins by Meng, Xiangzhi, Krumm, Brian, Li, Yongchao, Deng, Junpeng, Xiang, Yan

“…Human sterile alpha motif domain-containing 9 (SAMD9) protein is a host restriction factor for poxviruses, but it can be overcome by some poxvirus host-range…”
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EF-hand protein, EfhP, specifically binds Ca2+ and mediates Ca2+ regulation of virulence in a human pathogen Pseudomonas aeruginosa by Kayastha, Biraj B., Kubo, Aya, Burch-Konda, Jacob, Dohmen, Rosalie L., McCoy, Jacee L., Rogers, Rendi R., Mares, Sergio, Bevere, Justin, Huckaby, Annalisa, Witt, William, Peng, Shuxia, Chaudhary, Bharat, Mohanty, Smita, Barbier, Mariette, Cook, Gabriel, Deng, Junpeng, Patrauchan, Marianna A.

“…Calcium (Ca 2+ ) is well known as a second messenger in eukaryotes, where Ca 2+ signaling controls life-sustaining cellular processes. Although bacteria…”
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Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase by Deng, Junpeng, Lewis, Patrick A, Greggio, Elisa, Sluch, Eli, Beilina, Alexandra, Cookson, Mark R

“…Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of Parkinson's disease (PD). LRRK2 contains a Ras of complex proteins (ROC) domain…”
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Bladder Cancer: Immunotherapy and Pelvic Lymph Node Dissection by Fan, Zhongru, Deng, Junpeng, Wang, Yutao, Fan, Xin, Xie, Jianjun

“…Bladder cancer, a common malignancy of the urinary system, is routinely treated with radiation, chemotherapy, and surgical excision. However, these strategies…”
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Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer by Pathak, Prabhat Kumar, Peng, Shuxia, Meng, Xiangzhi, Han, Yue, Zhang, Bing, Zhang, Fushun, Xiang, Yan, Deng, Junpeng

“…Cellular membranes are maintained as closed compartments, broken up only transiently during membrane reorganization or lipid transportation. However,…”
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Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein by Krumm, Brian, Meng, Xiangzhi, Li, Yongchao, Xiang, Yan, Deng, Junpeng

“…Human interleukin-18 (hIL-18) is a cytokine that plays an important role in inflammation and host defense against microbes. Its activity is regulated in vivo…”
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The Advanced Applications of 2D Materials in SERS by Liu, Yansheng, Qin, Zhenle, Deng, Junpeng, Zhou, Jin, Jia, Xiaobo, Wang, Guofu, Luo, Feng

“…Surface-enhanced Raman scattering (SERS) as a label-free, non-contact, highly sensitive, and powerful technique has been widely applied in determining bio- and…”
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Structure-function analysis of vaccinia virus H7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication by Kolli, Swapna, Meng, Xiangzhi, Wu, Xiang, Shengjuler, Djoshkun, Cameron, Craig E, Xiang, Yan, Deng, Junpeng

“…Phosphoinositides and phosphoinositide binding proteins play a critical role in membrane and protein trafficking in eukaryotes. Their critical role in…”
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A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein by Krumm, Brian, Meng, Xiangzhi, Wang, Zhixin, Xiang, Yan, Deng, Junpeng

“…Interleukin 18 (IL18) is a cytokine that plays an important role in inflammation as well as host defense against microbes. Mammals encode a soluble inhibitor…”
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Analysis of the Role of Vaccinia Virus H7 in Virion Membrane Biogenesis with an H7-Deletion Mutant by Meng, Xiangzhi, Wu, Xiang, Yan, Bo, Deng, Junpeng, Xiang, Yan

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structure Function Studies of Vaccinia Virus Host Range Protein K1 Reveal a Novel Functional Surface for Ankyrin Repeat Proteins by Li, Yongchao, Meng, Xiangzhi, Xiang, Yan, Deng, Junpeng

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Research on a novel STATCOM based on hybrid cascaded multi-level converter and its coordination control strategy by Du, Yi, Hu, Pengfei, Deng, Junpeng, Lin, Hongyang, Li, Meng

“…A novel static synchronous compensator (STATCOM) based on hybrid cascaded multi-level converter (HCMC) is presented in this study, i.e HCMC-STATCOM, which…”
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