Search Results - "Deng, Jenny"
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Protocol to fabricate elastomer microwells for three-dimensional culture of primary adipocytes
Published in STAR protocols (20-09-2024)“…Our understanding of how adipocytes influence metabolic signaling, immune function, and cancer progression remains limited as the culture of primary adipocytes…”
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1251 SERUM BIOMARKER SIGNATURE IS PREDICTIVE OF THE RISK OF HEPATOCELLULAR CANCER IN PATIENTS WITH CIRRHOSIS
Published in Gastroenterology (New York, N.Y. 1943) (18-05-2024)Get full text
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The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response
Published in Cancer research (Chicago, Ill.) (16-08-2022)“…African-American (AA) men are more likely to be diagnosed with and die from prostate cancer than European American (EA) men. Despite the central role of the…”
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Postnatal induction of transforming growth factor β signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma
Published in Arthritis and rheumatism (01-01-2007)“…Objective Increased signaling by transforming growth factor β (TGFβ) has been implicated in systemic sclerosis (SSc; scleroderma), a complex disorder of…”
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Abstract A008: Elucidating the effects of the Alzheimer's disease associated gene BIN1 on cancer tumorigenesis
Published in Cancer research (Chicago, Ill.) (02-06-2023)“…Abstract Purpose- BIN1 is in deleted in ~5% of all prostate cancer (PC) patients and interestingly is highly enriched in the Speckle-type POZ protein (SPOP)…”
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Inhibition of GATA2 in prostate cancer by a clinically available small molecule
Published in Endocrine-related cancer (01-01-2022)“…Castration-resistant prostate cancer (CRPC) remains highly lethal and in need of novel, actionable therapeutic targets. The pioneer factor GATA2 is a…”
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Abstract 2077: Exploring the multifaceted efficacy of de novo lipogenesis inhibitor in cancer therapy
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Cancer cells frequently exhibit altered lipid metabolism to sustain their rapid growth and proliferation.Sterol Regulatory Element-Binding Proteins…”
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Abstract 3406: GATA2 a novel potential therapeutic target for treatment of neuroendocrine prostate cancer
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Neuroendocrine Prostate Cancer (NEPC) is a lethal and aggressive variant of prostate cancer (PC), arises from prostate adenocarcinoma, mainly as a…”
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Abstract 3013: Alzheimer’s-linked gene BIN1: Unraveling its unexpected role as a tumor suppressor in prostate cancer and influence on androgen receptor signaling
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Androgen-receptor signaling inhibitors (ARSI) have been shown to significantly alter the natural history of castration-resistant PCa (CRPC)…”
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Abstract 442: Developing a lipogenesis inhibitor for prostate cancer
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background: Prostate cancer (PC) is the single most common and second most lethal cancer in men. Despite therapeutic advances in androgen receptor…”
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Transcriptomic insights into the genetic basis of mammalian limb diversity
Published in BMC evolutionary biology (23-03-2017)“…From bat wings to whale flippers, limb diversification has been crucial to the evolutionary success of mammals. We performed the first transcriptome-wide study…”
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Postnatal ablation of Sox9 in mouse cartilage
Published in Matrix biology (01-12-2008)Get full text
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Smooth muscle cell differentiation: Mechanisms and models for vascular diseases
Published in Frontiers in biology (01-12-2017)“…BACKGROUND: Vascular smooth muscle cells (VSMCs) are mature cells that play critical roles in both normal and aberrantcardiovascular conditions. In response to…”
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