Search Results - "Deng, Ganlu"
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Ferroptosis: insight into the treatment of hepatocellular carcinoma
Published in Cancer cell international (13-11-2024)“…Hepatocellular carcinoma (HCC) is one of the most common malignances in the world, with high morbidity and mortality. Due to the hidden onset of symptoms,…”
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BMP4 promotes oxaliplatin resistance by an induction of epithelial-mesenchymal transition via MEK1/ERK/ELK1 signaling in hepatocellular carcinoma
Published in Cancer letters (28-12-2017)“…Bone morphogenetic protein-4 (BMP4) is a key regulator of epithelial-mesenchymal transition (EMT), which is crucial for cancer cells to acquire…”
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3
Influence of Hashimoto thyroiditis on diagnosis and treatment of thyroid nodules
Published in Frontiers in endocrinology (Lausanne) (23-12-2022)“…As the prevalence of Hashimoto's thyroiditis (HT) and thyroid cancer (TC) has been increasing dramatically in recent years, the association between the two…”
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Identification of a novel lncRNA prognostic signature and analysis of functional lncRNA AC115619.1 in hepatocellular carcinoma
Published in Frontiers in pharmacology (08-08-2023)“…Background: Hepatocellular carcinoma (HCC) is the deadliest malignancy. Long non-coding RNAs (lncRNAs) are involved in the development of multiple human…”
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FOXC2 Promotes Oxaliplatin Resistance by Inducing Epithelial-Mesenchymal Transition via MAPK/ERK Signaling in Colorectal Cancer
Published in OncoTargets and therapy (01-02-2020)“…Chemoresistance is a major obstacle to improving the survival rate of colorectal cancer (CRC) patients. Forkhead box protein C2 (FOXC2), a member of the…”
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BMP4 promotes metastasis of hepatocellular carcinoma by an induction of epithelial–mesenchymal transition via upregulating ID2
Published in Cancer letters (01-04-2017)“…Abstract The role of bone morphogenetic protein 4 (BMP4), a crucial epithelial–mesenchymal transition (EMT) mediator, in the progression of hepatocellular…”
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BMP4 enhances hepatocellular carcinoma proliferation by promoting cell cycle progression via ID2/CDKN1B signaling
Published in Molecular carcinogenesis (01-10-2017)“…Bone morphogenetic protein‐4 (BMP4) plays a crucial role in carcinogenesis, but the effects and signaling mechanisms of BMP4 in hepatocellular carcinoma (HCC)…”
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BMP4 promotes hepatocellular carcinoma proliferation by autophagy activation through JNK1-mediated Bcl-2 phosphorylation
Published in Journal of experimental & clinical cancer research (16-07-2018)“…Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP4), a member of the transforming…”
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ZEB1 Promotes Oxaliplatin Resistance through the Induction of Epithelial - Mesenchymal Transition in Colon Cancer Cells
Published in Journal of Cancer (01-01-2017)“…Oxaliplatin (OXA) chemotherapy is widely used in the clinical treatment of colon cancer. However, chemo-resistance is still a barrier to effective chemotherapy…”
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10
A cancer-associated fibroblast subtypes-based signature enables the evaluation of immunotherapy response and prognosis in bladder cancer
Published in iScience (15-09-2023)“…Bladder cancer (BLCA) is one of the most prevalent and heterogeneous urinary malignant tumors. Previous researches have reported a significant association…”
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The anti-tumor activities of Neferine on cell invasion and oxaliplatin sensitivity regulated by EMT via Snail signaling in hepatocellular carcinoma
Published in Scientific reports (30-01-2017)“…Tumor invasion and chemotherapy resistance, which are associated with epithelial-mesenchymal transition (EMT), remain as major challenges in hepatocellular…”
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12
Knockdown of Beclin‐1 impairs epithelial‐mesenchymal transition of colon cancer cells
Published in Journal of cellular biochemistry (01-08-2018)“…Activation of autophagy significantly affects cancer cell behaviors, such as proliferation, differentiation, and invasiveness. Epithelial‐to‐mesenchymal…”
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13
Honokiol induces ferroptosis in colon cancer cells by regulating GPX4 activity
Published in American journal of cancer research (01-01-2021)“…Colon cancer (CC) is a prevalent malignancy worldwide. Approaches to specifically induce tumor cell death have historically been a popular research topic…”
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14
BMP4 promotes the metastasis of gastric cancer by inducing epithelial-mesenchymal transition via ID1
Published in Journal of cell science (01-06-2020)“…Epithelial-mesenchymal transition (EMT) is a crucial process for cancer cells to acquire metastatic potential, which primarily causes death in gastric cancer…”
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15
Role of CCR1/5/7 in hepatocellular carcinoma: a study on prognostic evaluation, molecular subtyping, and association with immune infiltration
Published in Aging (Albany, NY.) (28-03-2024)“…This study aims to assess the prognostic value of the C-C motif chemokine receptor (CCR) gene family in hepatocellular carcinoma (HCC) and its relationship…”
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Increased long noncoding RNA LASP1‐AS is critical for hepatocellular carcinoma tumorigenesis via upregulating LASP1
Published in Journal of cellular physiology (01-08-2019)“…Aberrant long noncoding RNAs (lncRNA) have been proved to be associated with the many types of malignant tumors (including hepatocellular carcinoma [HCC]). In…”
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Nestin overexpression in hepatocellular carcinoma associates with epithelial-mesenchymal transition and chemoresistance
Published in Journal of experimental & clinical cancer research (13-07-2016)“…Nestin expression has been reported to be associated with the prognosis of many solid tumors including human hepatocellular carcinoma (HCC). The present study…”
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18
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC
Published in American journal of cancer research (01-01-2024)“…Diabetes mellitus (DM) is recognized as a risk factor for hepatocellular carcinoma (HCC). High glucose levels have been implicated in inducing…”
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A prognostic analysis of 895 cases of stage III colon cancer in different colon subsites
Published in International journal of colorectal disease (01-09-2015)“…Purpose Stage III colon cancer is currently treated as an entity with a unified therapeutic principle. The aim of the retrospective study is to explore the…”
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The Role of Type 2 Diabetes Mellitus-Related Risk Factors and Drugs in Hepatocellular Carcinoma
Published in Journal of hepatocellular carcinoma (01-01-2024)“…With changes in modern lifestyles, type 2 diabetes mellitus (T2DM) has become a global epidemic metabolic disease, and hepatocellular carcinoma (HCC) is one of…”
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