Search Results - "Deng, Caishu"

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells by Ghoreschi, Kamran, Brück, Jürgen, Kellerer, Christina, Deng, Caishu, Peng, Haiyan, Rothfuss, Oliver, Hussain, Rehana Z, Gocke, Anne R, Respa, Annedore, Glocova, Ivana, Valtcheva, Nadejda, Alexander, Eva, Feil, Susanne, Feil, Robert, Schulze-Osthoff, Klaus, Rupec, Rudolf A, Lovett-Racke, Amy E, Dringen, Ralf, Racke, Michael K, Röcken, Martin

“…Fumarates improve multiple sclerosis (MS) and psoriasis, two diseases in which both IL-12 and IL-23 promote pathogenic T helper (Th) cell differentiation…”
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Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer by Zhao, Yingchun, Deng, Caishu, Wang, Jiarui, Xiao, Jing, Gatalica, Zoran, Recker, Robert R., Xiao, Gary Guishan

“…In order to understand how microRNAs (miRNAs) regulate breast cancer tumorigenesis, a miRNA expression microarray screening was performed using RNA from…”
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miR-141 modulates androgen receptor transcriptional activity in human prostate cancer cells through targeting the small heterodimer partner protein by Xiao, Jing, Gong, Ai-Yu, Eischeid, Alex N., Chen, Dongqing, Deng, Caishu, Young, Charles Y.F., Chen, Xian-Ming

“…BACKGROUND Aberrant expressions of microRNAs, including upregulation of miR‐141, are closely associated with the tumorigenesis of prostate cancer (PCa). The…”
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Breast Cancer Migration and Invasion Depend on Proteasome Degradation of Regulator of G-Protein Signaling 4 by YAN XIE, WOLFF, Dennis W, TAOTAO WEI, BO WANG, DENG, Caishu, KIRUI, Joseph K, HAIHONGJIANG, JIANBING QIN, ABEL, Peter W, YAPING TUN

“…Aberrant signaling through G-protein coupled receptors promotes metastasis, the major cause of breast cancer death. We identified regulator of G-protein…”
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Prevalence of Barrett Esophagus in First-Degree Relatives of Patients With Esophageal Adenocarcinoma by Juhasz, Arpad, Mittal, Sumeet K, Lee, Tommy H, Deng, Caishu, Chak, Amitabh, Lynch, Henry T

“…AIMThe aim of this study is to determine the prevalence of Barrett esophagus (BE) in first-degree relatives of patients with esophageal adenocarcinoma (EAC)…”
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Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth by Wolff, Dennis W., Xie, Yan, Deng, Caishu, Gatalica, Zoran, Yang, Mingjie, Wang, Bo, Wang, Jincheng, Lin, Ming-Fong, Abel, Peter W., Tu, Yaping

“…G‐protein‐coupled receptor (GPCR)‐stimulated androgen‐independent activation of androgen receptor (AR) contributes to acquisition of a hormone‐refractory…”
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Animal Models of Myasthenia Gravis by Christadoss, Premkumar, Poussin, Mathilde, Deng, Caishu

“…Myasthenia gravis (MG) is an antibody-mediated, autoimmune neuromuscular disease. Animal models of experimental autoimmune myasthenia gravis (EAMG) can be…”
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IL-1 Receptor-Associated Kinase 1 Regulates Susceptibility to Organ-Specific Autoimmunity by Deng, Caishu, Radu, Caius, Diab, Asim, Tsen, May F, Hussain, Rehana, Cowdery, John S, Racke, Michael K, Thomas, James A

“…Infections often precede the development of autoimmunity. Correlation between infection with a specific pathogen and a particular autoimmune disease ranges…”
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let-7 microRNAs induce tamoxifen sensitivity by downregulation of estrogen receptor α signaling in breast cancer by Zhao, Yingchun, Deng, Caishu, Lu, Weida, Xiao, Jing, Ma, Danjun, Guo, Mingxi, Recker, Robert R, Gatalica, Zoran, Wang, Zhaoyi, Xiao, Gary Guishan

“…MicroRNAs (miRNAs) play an important regulatory role in breast tumorigenesis. Previously, we found that let-7 miRNAs were downregulated significantly in…”
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miR-221 suppresses ICAM-1 translation and regulates interferon-gamma-induced ICAM-1 expression in human cholangiocytes by Hu, Guoku, Gong, Ai-Yu, Liu, Jun, Zhou, Rui, Deng, Caishu, Chen, Xian-Ming

“…Aberrant cholangiocyte reactions in response to inflammatory stimuli are important pathogenic factors for the persistent biliary inflammation in patients with…”
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Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion by Xie, Yan, Abel, Peter W., Kirui, Joseph K., Deng, Caishu, Sharma, Poonam, Wolff, Dennis W., Toews, Myron L., Tu, Yaping

“…Metastasis is the major cause of breast cancer mortality. We recently reported that aberrant G-protein coupled receptor (GPCR) signaling promotes breast cancer…”
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A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion by Rao, V H, Kandel, A, Lynch, D, Pena, Z, Marwaha, N, Deng, C, Watson, P, Hansen, L A

“…Increased activation of epidermal growth factor receptor (EGFR) family members such as HER2/Erbb2 can result in more aggressive disease, resistance to…”
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Phosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations by Jiang, Haihong, Abel, Peter W, Toews, Myron L, Deng, Caishu, Casale, Thomas B, Xie, Yan, Tu, Yaping

“…Phosphoinositide 3-kinase gamma (PI3Kgamma) has been implicated in the pathogenesis of asthma, but its mechanism has been considered indirect, through release…”
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Identification of upregulated phosphoinositide 3-kinase I3 as a target to suppress breast cancer cell migration and invasion by Xie, Yan, Abel, Peter, Kirui, Joseph, Deng, Caishu, Sharma, Poonam, Wolff, Dennis, Toews, Myron, Tu, Yaping

“…Metastasis is the major cause of breast cancer mortality. We recently reported that aberrant G-protein coupled receptor (GPCR) signaling promotes breast cancer…”
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Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis by Diab, Asim, Deng, Caishu, Smith, Jeff D, Hussain, Rehana Z, Phanavanh, Bounleut, Lovett-Racke, Amy E, Drew, Paul D, Racke, Michael K

“…Peroxisome proliferator-activated receptors (PPAR) are members of a nuclear hormone receptor superfamily that includes receptors for steroids, retinoids, and…”
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Inhibition of Protein Phosphorylation in MIA Pancreatic Cancer Cells: Confluence of Metabolic and Signaling Pathways by Zhang, Hengwei, Cao, Rui, Lee, Wai-Nang Paul, Deng, Caishu, Zhao, Yingchun, Lappe, Joan, Recker, Robert, Yen, Yun, Wang, Qi, Tsai, Ming-Ying, Go, Vay Liang, Xiao, Gary Guishan

“…Oxythiamine (OT), a transketolase inhibitor, is known to inhibit pancreatic cancer cell proliferation. In this study, we investigated the effect of inhibition…”
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Prevalence of Barrett's Esophagus in first degree relatives of patients with esophageal adenocarcinoma by Juhasz, Arpad, Mittal, Sumeet K, Lee, Tommy H, Deng, Caishu, Chak, Amitabh, Lynch, Henry T

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Abstract 5188: Phosphoinositide 3-kinase γ: Implications in breast cancer metastasis by Xie, Yan, Kirui, Joseph K., Jiang, Haihong, Deng, Caishu, Tu, Yaping

“…Abstract Metastasis is the major cause of breast cancer mortality. Type I phosphatidylinositol 3-kinases (PI3Ks), including α, β, γ and δ, play a pivotal role…”
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Targeting G protein‐coupled receptor signaling to suppress breast cancer metastasis by Tu, Yaping, Xie, Yan, Wolff, Dennis W., Kirui, Joseph K., Jiang, Haihong, Deng, Caishu, Abel, Peter W.

“…Excessive signaling from G protein‐coupled receptors (GPCRs) promotes metastasis, the major cause of breast cancer death. Since breast cancer metastasis could…”
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Gβγ‐activated phosphoinositide 3‐kinase γ regulates airway smooth muscle contraction by modulating calcium oscillations by Jiang, Haihong, Abel, Peter W, Toews, Myron L, Deng, Caishu, Casale, Thomas B, Xie, Yan, Tu, Yaping

“…Airway smooth muscle (ASM) contractile hyper‐responsiveness plays a critical role in asthma. Muscarinic receptors in ASM convey bronchoconstrictor signals by…”
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