Search Results - "Deneyer, Noémie"
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Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1
Published in PloS one (2015)“…The homeodomain transcription factor Hoxa2 interacts with the RING-finger type E3 ubiquitin ligase RCHY1 and induces its proteasomal degradation. In this work,…”
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HOXA1 Is an Antagonist of ERα in Breast Cancer
Published in Frontiers in oncology (18-08-2021)“…Breast cancer is a heterogeneous disease and the leading cause of female cancer mortality worldwide. About 70% of breast cancers express ERα. HOX proteins are…”
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KPC2 relocalizes HOXA2 to the cytoplasm and decreases its transcriptional activity
Published in Biochimica et biophysica acta (01-10-2015)“…Regulation of transcription factor activity relies on molecular interactions or enzymatic modifications which influence their interaction with DNA…”
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HOXA2 activity regulation by cytoplasmic relocation, protein stabilization and post-translational modification
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-09-2019)“…HOX proteins are homeodomain transcription factors critically involved in patterning animal embryos and controlling organogenesis. While the functions of HOX…”
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Historical evaluation of the in vivo adventitious virus test and its potential for replacement with next generation sequencing (NGS)
Published in Biologicals (01-02-2023)“…The Consortium on Adventitious Agent Contamination in Biomanufacturing (CAACB) collected historical data from 20 biopharmaceutical industry members on their…”
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