Search Results - "Denefle, P."

A Wide Variety of Mutations in the Parkin Gene Are Responsible for Autosomal Recessive Parkinsonism in Europe by Abbas, Nacer, Lücking, Christoph B., Ricard, Sylvain, Dürr, Alexandra, Bonifati, Vincenzo, De Michele, Giuseppe, Bouley, Sandrine, Vaughan, Jenny R., Gasser, Thomas, Marconi, Roberto, Broussolle, Emmanuel, Brefel-Courbon, Christine, Harhangi, Biswadjiet S., Oostra, Ben A., Fabrizio, Edito, Böhme, Georg A., Pradier, Laurent, Wood, Nick W., Filla, Alessandro, Meco, Giuseppe, Denefle, Patrice, Agid, Yves, Brice, Alexis

“…Autosomal recessive juvenile parkinsonism (AR-JP, PARK2; OMIM 602544), one of the monogenic forms of Parkinson's disease (PD), was initially described in…”
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Ensemble Of Neural Networks For High Endothelial Venules Detection In Meca-79 Immunohistochemistry Images by Abreu, A., Franchet, C., Frenois, F-X., Brousset, P., Girard, J. P., Denefle, P., Naegel, B., Wemmert, C.

“…The presence of high endothelial venules (HEVs) in the tumor micro-environment is associated with favorable clinical out-come in breast cancer and other human…”
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Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-I-transgenic rabbits by DUVERGER, N, KRUTH, H, DENEFLE, P, EMMANUEL, F, CAILLAUD, J.-M, VIGLIETTA, C, CASTRO, G, TAILLEUX, A, FIEVET, C, FRUCHART, J. C, HOUDEBINE, L. M

“…Prospective epidemiological studies support the hypothesis that high levels of high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) A-I limit…”
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Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit by Yeh, P, Dedieu, J F, Orsini, C, Vigne, E, Denefle, P, Perricaudet, M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations by VAN DE WARRENBURG, B. P. C, LAMMENS, M, LÜCKING, C. B, DENEFLE, P, WESSELING, P, BOOIJ, J, PRAAMSTRA, P, QUINN, N, BRICE, A, HORSTINK, M. W. I. M

“…A Dutch family with autosomal recessive early-onset parkinsonism showed a heterozygous missense mutation in combination with a heterozygous exon deletion in…”
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Tracking Cancer Genetic Evolution using OncoTrack by Talukder, Asoke K., Agarwal, Mahima, Buetow, Kenneth H., Denèfle, Patrice P.

“…It is difficult for existing methods to quantify, and track the constant evolution of cancers due to high heterogeneity of mutations. However, structural…”
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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1 by Piette, Jean-Charles, Rust, Stephan, Denèfle, Patrice, Funke, Harald, Brewer, H. Bryan, Real, José, Assmann, Gerd, Rosier, Marie, Duverger, Nicolas, Deleuze, Jean-Francois, Amoura, Zahir

“…Tangier disease (TD) was first discovered nearly 40 years ago in two siblings living on Tangier Island. This autosomal co-dominant condition is characterized…”
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Liraglutide has potent anti-inflammatory and anti-catabolic activity in two cell-types implicated in osteoarthritis by Berenbaum, F., Meurot, C., Sudre, L., Bismuth, K., Rattenbach, R., Denefle, P., Martin, C., Jacques, C.

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Association between Early-Onset Parkinson's Disease and Mutations in the Parkin Gene by Lücking, Christoph B, Dürr, Alexandra, Bonifati, Vincenzo, Vaughan, Jenny, De Michele, Giuseppe, Gasser, Thomas, Harhangi, Biswadjiet S, Meco, Giuseppe, Denèfle, Patrice, Wood, Nicholas W, Agid, Yves, Nicholl, D, Breteler, M.M.B, Oostra, B.A, De Mari, M, Marconi, R, Filla, A, Bonnet, A.-M, Broussolle, E, Pollak, P, Rascol, O, Rosier, M, Arnould, Arnould, Brice, Alexis

“…Parkinson's disease is one of the most frequent neurodegenerative disorders, with a prevalence of 1 to 2 percent among persons older than 65 years of age. 1 It…”
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Phosphorylation of human recombinant tyrosine hydroxylase isoforms 1 and 2: an additional phosphorylated residue in isoform 2, generated through alternative splicing by LE BOURDELLES, B, HORELLOU, P, LE CAER, J.-P, DENEFLE, P, LATTA, M, HAAVIK, J, GUIBERT, B, MAYAUX, J.-F, MALLET, J

“…The single human tyrosine hydroxylase (TH) gene generates four different mRNA species through alternative splicing events. TH-1 and TH-2 mRNAs are expressed…”
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Mechanism of Inhibition of Protein Phosphatase 1 by DARPP-32: Studies with Recombinant DARPP-32 and Synthetic Peptides by Desdouits, F., Cheetham, J.J., Huang, H.B., Kwon, Y.G., Silva, E.F.D.E., Denefle, P., Ehrlich, M.E., Nairn, A.C., Greengard, P., Girault, J.A.

“…The mechanism of inhibition of protein phosphatase-1 catalytic subunit (PP-1c) by recombinant DARPP-32 and synthetic peptides was studied. DARPP-32 was…”
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Introduction to gene therapy: a clinical aftermath by Denèfle, Patrice P

“…Despite three decades of huge progress in molecular genetics, in cloning of disease causative gene as well as technology breakthroughs in viral biotechnology,…”
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Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice by Berthou, L, Duverger, N, Emmanuel, F, Langouët, S, Auwerx, J, Guillouzo, A, Fruchart, J C, Rubin, E, Denèfle, P, Staels, B, Branellec, D

“…The regulation of liver apolipoprotein (apo) A-I gene expression by fibrates was studied in human apo A-I transgenic mice containing a human genomic DNA…”
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Endothelial Derived Vasorelaxation Is Impaired in Human APO A-I Transgenic Rabbits by Lebuffe, G., Boullier, A., Tailleux, A., Delfly, B., Dupuis, B., Fruchart, J.C., Duverger, N., Emmanuel, F., Denefle, P., Vallet, B., Duriez, P.

“…Endothelium-derived relaxing factor (nitric oxide: NO) may provide an endogenous defence against atherosclerosis which impairs endothelium-dependent vascular…”
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Complete Genomic Sequence of the Human ABCA1 Gene: Analysis of the Human and Mouse ATP-Binding Cassette A Promoter by Santamarina-Fojo, Silvia, Peterson, Katherine, Knapper, Catherine, Qiu, Yang, Freeman, Lita, Cheng, Jan-Fang, Osorio, Jose, Remaley, Alan, Yang, Xiao-Ping, Haudenschild, Changting, Prades, Catherine, Chimini, Giovanna, Blackmon, Eunice, Francois, Teena, Duverger, Nicholas, Rubin, Edward M., Rosier, Marie, Denefle, Patrice, Fredrickson, Donald S., Brewer, H. Bryan

“…The ABCA1 gene, a member of the ATP-binding cassette A (ABCA1) transporter superfamily, encodes a membrane protein that facilitates the cellular efflux of…”
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Regulation of Rat Liver Apolipoprotein A‐I, Apolipoprotein A‐II and Acyl‐Coenzyme A Oxidase Gene Expression by Fibrates and Dietary Fatty Acids by Berthou, Laurence, Saladin, Régis, Yaqoob, Parveen, Branellec, Didier, Calder, Philip, Fruchart, Jean‐Charles, Denèfle, Patrice, Auwerx, Johan, Staels, Bart

“…The regulation by fibrates and dietary fatty acids of the hepatic gene expression of apolipoproteins (apo) A‐I and A‐II, the major protein constituents of…”
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Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34 by Annilo, T, Shulenin, S, Chen, Z Q, Arnould, I, Prades, C, Lemoine, C, Maintoux-Larois, C, Devaud, C, Dean, M, Denèfle, P, Rosier, M

“…The ABCA subfamily of ABC transporters includes ten members to date. In this study, we describe an additional gene, ABCA12. Four full-length cDNA sequences…”
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Efficient adenovirus-mediated ectopic gene expression of human lipoprotein lipase in human hepatic (HepG2) cells by Liu, G, Excoffon, K J, Benoit, P, Ginzinger, D G, Miao, L, Ehrenborg, E, Duverger, N, Denefle, P P, Hayden, M R, Lewis, M E

“…Gene therapy to deliver and express a corrective lipoprotein lipase (LPL) gene may improve the lipid profile and reduce the morbidity and potential atherogenic…”
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Apolipoprotein A-I(R151C)Paris is defective in activation of lecithin : cholesterol acyltransferase but not in initial lipid binding, formation of reconstituted lipoproteins, or promotion of cholesterol efflux by DAUM, U, LANGER, C, ASSMANN, G, VON ECKARDSTEIN, A, DUVERGER, N, EMMANUEL, F, BENOIT, P, DENEFLE, P, CHIRAZI, A, CULLEN, P, PRITCHARD, P. H, BRUCKERT, E

“…ApoA-I(R151)Paris is a natural apolipoprotein (apo) A-I variant that is associated with low levels of high-density lipoprotein cholesterol (HDL-cholesterol)…”
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Protection Against Atherogenesis in Mice Mediated by Human Apolipoprotein A-IV by Duverger, Nicolas, Tremp, Günter, Caillaud, Jean-Michel, Emmanuel, Florence, Castro, Graciela, Fruchart, Jean-Charles, Steinmetz, Armin, Denèfle, Patrice

“…Apollpoproteins are protein constituents of plasma lipid transport particles. Human apolipoprotein A-IV (apoA-IV) was expressed in the liver of C57BL/6 mice…”
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