Search Results - "Dencker, Lennart"

Refine Results
  1. 1

    Faced with inequality: chicken do not have a general dosage compensation of sex-linked genes by Ellegren, Hans, Hultin-Rosenberg, Lina, Brunström, Björn, Dencker, Lennart, Kultima, Kim, Scholz, Birger

    Published in BMC biology (20-09-2007)
    “…The contrasting dose of sex chromosomes in males and females potentially introduces a large-scale imbalance in levels of gene expression between sexes, and…”
    Get full text
    Journal Article
  2. 2

    Effects of the histone deacetylase inhibitor valproic acid on human pericytes in vitro by Karén, Jakob, Rodriguez, Alejandro, Friman, Tomas, Dencker, Lennart, Sundberg, Christian, Scholz, Birger

    Published in PloS one (22-09-2011)
    “…Microvascular pericytes are of key importance in neoformation of blood vessels, in stabilization of newly formed vessels as well as maintenance of angiostasis…”
    Get full text
    Journal Article
  3. 3

    Exposure to brominated flame retardant PBDE-99 affects cytoskeletal protein expression in the neonatal mouse cerebral cortex by Alm, Henrik, Kultima, Kim, Scholz, Birger, Nilsson, Anna, Andrén, Per E., Fex-Svenningsen, Åsa, Dencker, Lennart, Stigson, Michael

    Published in Neurotoxicology (Park Forest South) (01-07-2008)
    “…Polybrominated diphenyl ethers (PBDEs) are environmental contaminants found in human and animal tissues worldwide. Neonatal exposure to the flame retardant…”
    Get full text
    Journal Article
  4. 4

    Valproic Acid Teratogenicity: A Toxicogenomics Approach by Kultima, Kim, Nyström, Anna-Maja, Scholz, Birger, Gustafson, Anne-Lee, Dencker, Lennart, Stigson, Michael

    Published in Environmental health perspectives (15-08-2004)
    “…Embryonic development is a highly coordinated set of processes that depend on hierarchies of signaling and gene regulatory networks, and the disruption of such…”
    Get full text
    Journal Article
  5. 5

    Sex-dependent gene expression in early brain development of chicken embryos by Scholz, Birger, Kultima, Kim, Mattsson, Anna, Axelsson, Jeanette, Brunström, Björn, Halldin, Krister, Stigson, Michael, Dencker, Lennart

    Published in BMC neuroscience (15-02-2006)
    “…Differentiation of the brain during development leads to sexually dimorphic adult reproductive behavior and other neural sex dimorphisms. Genetic mechanisms…”
    Get full text
    Journal Article
  6. 6

    Valproic Acid Teratogenicity: A Toxicogenomics Approach by Kultima, Kim, Nyström, Anna-Maja, Scholz, Birger, Gustafson, Anne-Lee, Dencker, Lennart, Stigson, Michael

    Published in Environmental health perspectives (01-08-2004)
    “…Embryonic development is a highly coordinated set of processes that depend on hierarchies of signaling and gene regulatory networks, and the disruption of such…”
    Get full text
    Journal Article
  7. 7

    The Identification of a 9-cis Retinol Dehydrogenase in the Mouse Embryo Reveals a Pathway for Synthesis of 9-cis Retinoic Acid by Romert, Anna, Tuvendal, Paulina, Simon, Andras, Dencker, Lennart, Eriksson, Ulf

    “…The ligand-controlled retinoic acid (RA) receptors and retinoid X receptors are important for several physiological processes, including normal embryonic…”
    Get full text
    Journal Article
  8. 8

    The cellular retinoic acid binding proteins by Donovan, Mark, Olofsson, Birgitta, Gustafson, Anne-Lee, Dencker, Lennart, Eriksson, Ulf

    “…The two cellular retinoic acid binding proteins, CRABP I and CRABP II, belong to a family of small cytosolic lipid binding proteins and are highly conserved…”
    Get full text
    Journal Article Conference Proceeding
  9. 9

    Valproic Acid–Induced Deregulation In Vitro of Genes Associated In Vivo with Neural Tube Defects by Jergil, Måns, Kultima, Kim, Gustafson, Anne-Lee, Dencker, Lennart, Stigson, Michael

    Published in Toxicological sciences (01-03-2009)
    “…The utility of an in vitro system to search for molecular targets and markers of developmental toxicity was explored, using microarrays to detect genes…”
    Get full text
    Journal Article
  10. 10

    Metabolism of arsenobetaine in mice, rats and rabbits by Vahter, M, Marafante, E, Dencker, L

    Published in The Science of the total environment (01-09-1983)
    “…The distribution, retention and biotransformation of arsenobetaine, the most common organic arsenic compound in fish and crustacea, have been studied in mice,…”
    Get more information
    Journal Article
  11. 11

    Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells by Jergil, Måns, Forsberg, Maud, Salter, Hugh, Stockling, Kenneth, Gustafson, Anne-Lee, Dencker, Lennart, Stigson, Michael

    Published in Toxicological sciences (01-06-2011)
    “…Prediction of developmental toxicity in vitro could be based on short-time toxicogenomic endpoints in embryo-derived cell lines. Microarray studies in P19…”
    Get full text
    Journal Article
  12. 12

    Mercury in the Spinal Cord After Inhalation of Mercury by Roos, Per M., Dencker, Lennart

    Published in Basic & clinical pharmacology & toxicology (01-08-2012)
    “…Amyotrophic lateral sclerosis (ALS) affects anterior horn cells of the spinal cord causing an indolent slow and steady deterioration of muscle strength leading…”
    Get full text
    Journal Article
  13. 13
  14. 14

    Towards a European Strategy for Medicines Research (2014–2020): The EUFEPS Position Paper on Horizon 2020 by Gaspar, Rogério, Aksu, Buket, Cuine, Alain, Danhof, Meindert, Takac, Milena Jadrijevic-Mladar, Linden, Hans H., Link, Andreas, Muchitsch, Eva-Maria, Wilson, Clive G., Öhrngren, Per, Dencker, Lennart

    “…Executive summary: As to the alignment of “Horizon 2020”, ir is a more integrated approach to European science policy than expressed in the proposals…”
    Get full text
    Journal Article
  15. 15

    Network on veterinary medicines initiated by the European Federation For Pharmaceutical Sciences by Mochel, J. P., Tyden, E., Hellmann, K., Vendrig, J. C., Şenel, S., Dencker, L., Cristina, R. T., Linden, H., Schmerold, I.

    “…The European Federation for Pharmaceutical Sciences (EUFEPS) was founded 25 years ago by more than 20 national pharmaceutical societies and faculty members. As…”
    Get full text
    Journal Article
  16. 16

    Metabolism of arsenocholine in mice, rats and rabbits by Marafante, E, Vahter, M, Dencker, L

    Published in The Science of the total environment (01-01-1984)
    “…The distribution, retention and biotransformation of arsenocholine, an organic arsenic compound present in certain seafood, have been studied in rats, mice and…”
    Get more information
    Journal Article
  17. 17

    Early transcriptional responses in mouse embryos as a basis for selection of molecular markers predictive of valproic acid teratogenicity by Kultima, Kim, Jergil, Måns, Salter, Hugh, Gustafson, Anne-Lee, Dencker, Lennart, Stigson, Michael

    Published in Reproductive toxicology (Elmsford, N.Y.) (01-11-2010)
    “…Cell-based in vitro assays would potentially reduce animal testing in preclinical drug development. Mouse embryos exposed to the teratogenic drug valproic acid…”
    Get full text
    Journal Article
  18. 18

    Proteomic Evaluation of Neonatal Exposure to 2,2′,4,4′,5-Pentabromodiphenyl Ether by Alm, Henrik, Scholz, Birger, Fischer, Celia, Kultima, Kim, Viberg, Henrik, Eriksson, Per, Dencker, Lennart, Stigson, Michael

    Published in Environmental health perspectives (01-02-2006)
    “…Exposure to the brominated flame retardant 2,2′,4,4′,5-pentabromodiphenyl ether (PBDE-99) during the brain growth spurt disrupts normal brain development in…”
    Get full text
    Journal Article
  19. 19

    In Vitro Neurotoxicity of PBDE-99: Immediate and Concentration-Dependent Effects on Protein Expression in Cerebral Cortex Cells by Alm, Henrik, Scholz, Birger, Kultima, Kim, Nilsson, Anna, Andrén, Per E, Savitski, Mikhail M, Bergman, Åke, Stigson, Michael, Fex-Svenningsen, Åsa, Dencker, Lennart

    Published in Journal of proteome research (05-03-2010)
    “…Polybrominated diphenyl ethers (PBDEs) are commonly used flame retardants in various consumer products. Pre- and postnatal exposure to congeners of PBDEs…”
    Get full text
    Journal Article
  20. 20

    A novel infrastructure for chemical safety predictions with focus on human health by Spjuth, Ola, Willighagen, Egon, Hammerling, Ulf, Dencker, Lennart, Grafström, Roland

    Published in TOXICOLOGY LETTERS (2012)
    “…A major objective of Computational Toxicology is to provide reliable and useful estimates in silico of (potentially) harmful actions of chemicals in humans…”
    Get full text
    Journal Article Conference Proceeding