Search Results - "Denbigh, Joanna"

3D DESI-MS lipid imaging in a xenograft model of glioblastoma: a proof of principle by Henderson, Fiona, Jones, Emrys, Denbigh, Joanna, Christie, Lidan, Chapman, Richard, Hoyes, Emmy, Claude, Emmanuelle, Williams, Kaye J., Roncaroli, Federico, McMahon, Adam

“…Desorption electrospray ionisation mass spectrometry (DESI-MS) can image hundreds of molecules in a 2D tissue section, making it an ideal tool for mapping…”
Get full text

Fatty-Acid Uptake in Prostate Cancer Cells Using Dynamic Microfluidic Raman Technology by Tang, Nga-Tsing, D Snook, Richard, Brown, Mick D, Haines, Bryan A, Ridley, Andrew, Gardner, Peter, Denbigh, Joanna L

“…It is known that intake of dietary fatty acid (FA) is strongly correlated with prostate cancer progression but is highly dependent on the type of FAs. High…”
Get full text

Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques by Denbigh, Joanna L., Perez-Guaita, David, Vernooij, Robbin R., Tobin, Mark J., Bambery, Keith R., Xu, Yun, Southam, Andrew D., Khanim, Farhat L., Drayson, Mark T., Lockyer, Nicholas P., Goodacre, Royston, Wood, Bayden R.

“…Acute myeloid leukaemia (AML) is a life threatening cancer for which there is an urgent clinical need for novel therapeutic approaches. A redeployed drug…”
Get full text

Analysis of Fixed and Live Single Cells Using Optical Photothermal Infrared with Concomitant Raman Spectroscopy by Spadea, Alice, Denbigh, Joanna, Lawrence, M. Jayne, Kansiz, Mustafa, Gardner, Peter

“…This paper reports the first use of a novel completely optically based photothermal method (O-PTIR) for obtaining infrared spectra of both fixed and living…”
Get full text

Tunicamycin induced endoplasmic reticulum changes in endothelial cells investigated in vitro by confocal Raman imaging by Bik, Ewelina, Mielniczek, Nikola, Jarosz, Magdalena, Denbigh, Joanna, Budzynska, Renata, Baranska, Malgorzata, Majzner, Katarzyna

“…This paper describes how tunicamycin (Tu), the most widely used pharmacological agent for inducing endoplasmic reticulum (ER) stress, interacts with…”
Get more information

Increased optical pathlength through aqueous media for the infrared microanalysis of live cells by Doherty, James, Zhang, Zhe, Wehbe, Katia, Cinque, Gianfelice, Gardner, Peter, Denbigh, Joanna

“…The study of live cells using Fourier transform infrared spectroscopy (FTIR) and FTIR microspectroscopy (FT-IRMS) intrinsically yields more information about…”
Get full text

Abstract 203: Automated, high throughput mass spectrometry imaging of serial sections for investigation of tumor heterogeneity in three dimensions by Jones, Emrys A., Henderson, Fiona, Coope, David, Denbigh, Joanna, Pringle, Steven, McMahon, Adam, Williams, Kaye

“…Abstract For the purpose of investigating the potential of automation and high throughput mass spectrometry imaging, we have combined a desorption electrospray…”
Get full text

Lipidomic and Metabolomic Analysis of Biological Response Mechanisms in Cancer Cells: A Multidisciplinary Approach by Denbigh, Joanna L

“…The 21st Century has seen a rise in incidence of complex diseases such as cancer and in the quest to develop essential new therapeutic options, the study of…”
Get full text