Search Results - "Den Blaauwen, Tanneke"
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Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli
Published in eLife (21-10-2016)“…The target of β-lactam antibiotics is the D,D-transpeptidase activity of penicillin-binding proteins (PBPs) for synthesis of 4→3 cross-links in the…”
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The Escherichia coli Outer Membrane β-Barrel Assembly Machinery (BAM) Anchors the Peptidoglycan Layer by Spanning It with All Subunits
Published in International journal of molecular sciences (12-02-2021)“…Gram-negative bacteria possess a three-layered envelope composed of an inner membrane, surrounded by a peptidoglycan (PG) layer, enclosed by an outer membrane…”
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Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division
Published in eLife (07-05-2015)“…To maintain cellular structure and integrity during division, Gram-negative bacteria must carefully coordinate constriction of a tripartite cell envelope of…”
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Early midcell localization of Escherichia coli PBP4 supports the function of peptidoglycan amidases
Published in PLoS genetics (23-05-2022)“…Insertion of new material into the Escherichia coli peptidoglycan (PG) sacculus between the cytoplasmic membrane and the outer membrane requires a…”
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Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB
Published in mBio (11-09-2018)“…Most bacteria and archaea use the tubulin homologue FtsZ as its central organizer of cell division. In Gram-negative bacteria, FtsZ recruits cytosolic,…”
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Validation of FRET Assay for the Screening of Growth Inhibitors of Escherichia coli Reveals Elongasome Assembly Dynamics
Published in International journal of molecular sciences (31-07-2015)“…The increase in antibiotic resistant bacteria demands the development of new antibiotics against preferably new targets. The common approach is to test…”
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The Bacterial DNA Binding Protein MatP Involved in Linking the Nucleoid Terminal Domain to the Divisome at Midcell Interacts with Lipid Membranes
Published in mBio (28-05-2019)“…Division ring formation at midcell is controlled by various mechanisms in , one of them being the linkage between the chromosomal Ter macrodomain and the…”
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PBP4 Is Likely Involved in Cell Division of the Longitudinally Dividing Bacterium Candidatus Thiosymbion Oneisti
Published in Antibiotics (Basel) (09-03-2021)“…Peptidoglycan (PG) is essential for bacterial survival and maintaining cell shape. The rod-shaped model bacterium has a set of seven endopeptidases that…”
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An Updated Model of the Divisome: Regulation of the Septal Peptidoglycan Synthesis Machinery by the Divisome
Published in International journal of molecular sciences (24-03-2022)“…The synthesis of a peptidoglycan septum is a fundamental part of bacterial fission and is driven by a multiprotein dynamic complex called the divisome. FtsW…”
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Differential bacterial surface display of peptides by the transmembrane domain of OmpA
Published in PloS one (25-08-2009)“…Peptide libraries or antigenic determinants can be displayed on the surface of bacteria through insertion in a suitable outer membrane scaffold protein. Here,…”
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Peptidoglycan Endopeptidase PBP7 Facilitates the Recruitment of FtsN to the Divisome and Promotes Peptidoglycan Synthesis in Escherichia coli
Published in Molecular microbiology (30-09-2024)“…Escherichia coli has many periplasmic hydrolases to degrade and modify peptidoglycan (PG). However, the redundancy of eight PG endopeptidases makes it…”
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Checks and Balances in Bacterial Cell Division
Published in mBio (26-02-2019)“…Assembly of the division machinery in Gram-negative and Gram-positive bacteria occurs in two time-dependent steps. First, the FtsZ proto-ring localizes at…”
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NlpI-Prc Proteolytic Complex Mediates Peptidoglycan Synthesis and Degradation via Regulation of Hydrolases and Synthases in Escherichia coli
Published in International journal of molecular sciences (15-11-2023)“…Balancing peptidoglycan (PG) synthesis and degradation with precision is essential for bacterial growth, yet our comprehension of this intricate process…”
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Is Longitudinal Division in Rod-Shaped Bacteria a Matter of Swapping Axis?
Published in Frontiers in microbiology (08-05-2018)“…The morphology of bacterial species shows a wealth of variation from star-shaped to spherical and rod- to spiral-shaped, to mention a few. Their mode of growth…”
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The Escherichia coli Outer Membrane β-Barrel Assembly Machinery (BAM) Crosstalks with the Divisome
Published in International journal of molecular sciences (09-11-2021)“…The BAM is a macromolecular machine responsible for the folding and the insertion of integral proteins into the outer membrane of diderm Gram-negative…”
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MreC and MreD balance the interaction between the elongasome proteins PBP2 and RodA
Published in PLoS genetics (28-12-2020)“…Rod-shape of most bacteria is maintained by the elongasome, which mediates the synthesis and insertion of peptidoglycan into the cylindrical part of the cell…”
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Toward a hyperstructure taxonomy
Published in Annual review of microbiology (01-01-2007)“…Bacterial cells contain many large, spatially extended assemblies of ions, molecules, and macromolecules, called hyperstructures, that are implicated in…”
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The Longitudinal Dividing Bacterium Candidatus Thiosymbion Oneisti Has a Natural Temperature-Sensitive FtsZ Protein with Low GTPase Activity
Published in International journal of molecular sciences (10-03-2022)“…FtsZ, the bacterial tubulin-homolog, plays a central role in cell division and polymerizes into a ring-like structure at midcell to coordinate other cell…”
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Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi‐enzyme complexes in Escherichia coli
Published in The EMBO journal (02-03-2020)“…The peptidoglycan (PG) sacculus provides bacteria with the mechanical strength to maintain cell shape and resist osmotic stress. Enlargement of the mesh‐like…”
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Timing of FtsZ Assembly in Escherichia coli
Published in Journal of Bacteriology (01-09-1999)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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