Search Results - "Dempster, Niall"

AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease by Nikolaou, Nikolaos, Gathercole, Laura L., Marchand, Lea, Althari, Sara, Dempster, Niall J., Green, Charlotte J., van de Bunt, Martijn, McNeil, Catriona, Arvaniti, Anastasia, Hughes, Beverly A., Sgromo, Bruno, Gillies, Richard S., Marschall, Hanns-Ulrich, Penning, Trevor M., Ryan, John, Arlt, Wiebke, Hodson, Leanne, Tomlinson, Jeremy W.

“…Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome. Steroid hormones and bile acids are potent regulators of hepatic…”
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Extensive weight loss reduces glycan age by altering IgG N-glycosylation by Greto, Valentina L., Cvetko, Ana, Štambuk, Tamara, Dempster, Niall J., Kifer, Domagoj, Deriš, Helena, Cindrić, Ana, Vučković, Frano, Falchi, Mario, Gillies, Richard S., Tomlinson, Jeremy W., Gornik, Olga, Sgromo, Bruno, Spector, Tim D., Menni, Cristina, Geremia, Alessandra, Arancibia-Cárcamo, Carolina V., Lauc, Gordan

“…Background Obesity, a major global health problem, is associated with increased cardiometabolic morbidity and mortality. Protein glycosylation is a frequent…”
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Alterations in plasma protein N-glycosylation after caloric restriction and bariatric surgery by Štambuk, Tamara, Kifer, Domagoj, Greto, Valentina L., Dempster, Niall J., Cvetko, Ana, Gillies, Richard S., Tomlinson, Jeremy W., Sgromo, Bruno, Mineo, Chieko, Shaul, Philip W., Lauc, Gordan, Lingvay, Ildiko, Geremia, Alessandra, Arancibia-Cárcamo, Carolina V.

“…Protein glycosylation is an enzymatic process known to reflect an individual’s physiologic state and changes thereof. The impact of metabolic interventions on…”
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Differential activity and expression of human 5β-reductase (AKR1D1) splice variants by Appanna, Nathan, Gibson, Hylton, Gangitano, Elena, Dempster, Niall J, Morris, Karen, George, Sherly, Arvaniti, Anastasia, Gathercole, Laura L, Keevil, Brian, Penning, Trevor M, Storbeck, Karl-Heinz, Tomlinson, Jeremy W, Nikolaou, Nikolaos

“…Steroid hormones, including glucocorticoids and androgens, exert a wide variety of effects in the body across almost all tissues. The steroid A-ring…”
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Outcomes following renal transplantation in older people: a retrospective cohort study by Dempster, Niall J, Ceresa, Carlo D L, Aitken, Emma, Kingsmore, David

“…The mean age of renal transplant recipients is rising, with age no longer considered a contraindication. Outcomes in older patients have not, however, been…”
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Urologists' usage and perceptions of urological apps by Dempster, Niall J, Risk, Rachel, Clark, Ross, Meddings, Robert N

“…We conducted a survey of urologists to document their patterns of app usage and perceptions of app quality, and to assess their interest in future app usage…”
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Effects of Caloric Restriction and Bariatric Surgery on Non-Alcoholic Fatty Liver Disease by Dempster, Niall

“…Non-alcoholic fatty liver disease (NAFLD) represents the hepatic manifestation of the metabolic syndrome. It encompasses a broad spectrum of severity, from…”
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PYY plays a key role in the resolution of diabetes following bariatric surgery in humans by Guida, Claudia, Stephen, Sam D., Watson, Michael, Dempster, Niall, Larraufie, Pierre, Marjot, Thomas, Cargill, Tamsin, Rickers, Lisa, Pavlides, Michael, Tomlinson, Jeremy, Cobbold, Jeremy F.L., Zhao, Chun-Mei, Chen, Duan, Gribble, Fiona, Reimann, Frank, Gillies, Richard, Sgromo, Bruno, Rorsman, Patrik, Ryan, John D., Ramracheya, Reshma D.

“…Bariatric surgery leads to early and long-lasting remission of type 2 diabetes (T2D). However, the mechanisms behind this phenomenon remain unclear. Among…”
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Optimal Treatment Strategies for cT2 Staged Adenocarcinoma of the Esophagus and the Gastroesophageal Junction: A Multinational, High-volume Center Retrospective Cohort Analysis by Wirsik, Naita M, Kooij, Cezanne D, Dempster, Niall, Crnovrsanin, Nerma, Donlon, Noel E, Uzun, Eren, Bhanot, Kunal, Nienhüser, Henrik, Polette, Daniela, Kewani, Kammy, Grimminger, Peter, Reim, Daniel, Seyfried, Florian, Fuchs, Hans F, Gisbertz, Suzanne S, Germer, Christoph-Thomas, Ruurda, Jelle P, Klevebro, Fredrik, Schröder, Wolfgang, Nilsson, Magnus, Reynolds, John V, Van Berge Henegouwen, Mark I, Markar, Sheraz, Van Hillegersberg, Richard, Schmidt, Thomas, Bruns, Christiane J

“…A multi-national high-volume center study was undertaken to evaluate outcomes after primary surgery (PS) or neoadjuvant treatment followed by surgery (NAT/S)…”
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AKR1D1 knockout mice develop a sex-dependent metabolic phenotype by Gathercole, Laura L, Nikolaou, Nikolaos, Harris, Shelley E, Arvaniti, Anastasia, Poolman, Toryn M, Hazlehurst, Jonathan M, Kratschmar, Denise V, Todorčević, Marijana, Moolla, Ahmad, Dempster, Niall, Pink, Ryan C, Saikali, Michael F, Bentley, Liz, Penning, Trevor M, Ohlsson, Claes, Cummins, Carolyn L, Poutanen, Matti, Odermatt, Alex, Cox, Roger D, Tomlinson, Jeremy W

“…Steroid 5β-reductase (AKR1D1) plays important role in hepatic bile acid synthesis and glucocorticoid clearance. Bile acids and glucocorticoids are potent…”
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Delayed graft function is a syndrome rather than a diagnosis by Aitken, Emma, Cooper, Claire, Dempster, Niall, McDermott, Michael, Ceresa, Carlo, Kingsmore, David

“…Delayed graft function is a significant prognostic indicator after renal transplantation. We hypothesized that delayed graft function is not a single entity,…”
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PYY plays a key role in the resolution of diabetes following bariatric surgery in humansResearch in context by Claudia Guida, Sam D. Stephen, Michael Watson, Niall Dempster, Pierre Larraufie, Thomas Marjot, Tamsin Cargill, Lisa Rickers, Michael Pavlides, Jeremy Tomlinson, Jeremy F.L. Cobbold, Chun-Mei Zhao, Duan Chen, Fiona Gribble, Frank Reimann, Richard Gillies, Bruno Sgromo, Patrik Rorsman, John D. Ryan, Reshma D. Ramracheya

“…Background: Bariatric surgery leads to early and long-lasting remission of type 2 diabetes (T2D). However, the mechanisms behind this phenomenon remain…”
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