Search Results - "Dempsey, William P."
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1
Structure and Function of an Actin-Based Filter in the Proximal Axon
Published in Cell reports (Cambridge) (05-12-2017)“…The essential organization of microtubules within neurons has been described; however, less is known about how neuronal actin is arranged and the functional…”
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2
PhOTO zebrafish: a transgenic resource for in vivo lineage tracing during development and regeneration
Published in PloS one (14-03-2012)“…Elucidating the complex cell dynamics (divisions, movement, morphological changes, etc.) underlying embryonic development and adult tissue regeneration…”
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3
Adaptive optics improves multiphoton super-resolution imaging
Published in Nature methods (01-09-2017)“…Adaptive optics and two-photon instant structured illumination microscopy are combined to provide improved super-resolution imaging within optically aberrating…”
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4
SHG nanoprobes: Advancing harmonic imaging in biology
Published in BioEssays (01-05-2012)“…Second harmonic generating (SHG) nanoprobes have recently emerged as versatile and durable labels suitable for in vivo imaging, circumventing many of the…”
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5
Probabilistic sensitivity analysis of biochemical reaction systems
Published in The Journal of chemical physics (07-09-2009)“…Sensitivity analysis is an indispensable tool for studying the robustness and fragility properties of biochemical reaction systems as well as for designing…”
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6
Regional synapse gain and loss accompany memory formation in larval zebrafish
Published in Proceedings of the National Academy of Sciences - PNAS (18-01-2022)“…Defining the structural and functional changes in the nervous system underlying learning and memory represents a major challenge for modern neuroscience…”
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7
In vivo single-cell labeling by confined primed conversion
Published in Nature methods (01-07-2015)“…Primed conversion of proteins such as Dendra2 confines photoconversion to a limited 3Dvolume through a sequential absorption process relying on illumination…”
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8
Surface functionalization of barium titanate SHG nanoprobes for in vivo imaging in zebrafish
Published in Nature protocols (01-09-2012)“…To address the need for a bright, photostable labeling tool that allows long-term in vivo imaging in whole organisms, we recently introduced second harmonic…”
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9
In vivo cell tracking using PhOTO zebrafish
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2014)“…By combining the strength of previously described in vivo cell tracking methodologies, we have recently generated a set of transgenic zebrafish lines, called…”
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10
Determination of the source of SHG verniers in zebrafish skeletal muscle
Published in Scientific reports (11-12-2015)“…SHG microscopy is an emerging microscopic technique for medically relevant imaging because certain endogenous proteins, such as muscle myosin lattices within…”
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11
An E3-ligase-based method for ablating inhibitory synapses
Published in Nature methods (01-08-2016)“…When studying neural circuitry, the ablation of synapses may be an alternative to optogenetic manipulation of neurons. A genetically encoded tool called GFE3…”
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12
Sharing Begins at Home: How Continuous and Ubiquitous FAIRness Can Enhance Research Productivity and Data Reuse
Published in Harvard data science review (01-07-2022)“…The broad sharing of research data is widely viewed as critical for the speed, quality, accessibility, and integrity of science. Despite increasing efforts to…”
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13
Resonance sonomanometry for noninvasive, continuous monitoring of blood pressure
Published in PNAS nexus (01-07-2024)“…Cardiovascular disease is the leading cause of death worldwide. Existing methods for continuous, noninvasive blood pressure (BP) monitoring suffer from poor…”
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14
Adaptive optics improves resolution and signal in multiphoton super-resolution imaging
Published in Nature methods (19-06-2017)“…We improve multiphoton structured illumination microscopy using a nonlinear guide-star to determine optical aberrations and a deformable mirror to correct…”
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15
Establishing a genetic and exogenous toolbox for studying multiple stages of vertebrate development in vivo
Published 01-01-2012“…Understanding of cell behavior during vertebrate development and repair has been greatly facilitated by advances in biological imaging. Importantly, more…”
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