Search Results - "Demozay, Damien"

Placental nutrient transporters adapt during persistent maternal hypoglycaemia in rats by Jensen, Vivi F H, Mølck, Anne-Marie, Nowak, Jette, Wohlfarth, Maria, Nüsken, Eva, Demozay, Damien, Nüsken, Kai-Dietrich, Bøgh, Ingrid B

“…Maternal malnutrition is associated with decreased nutrient transfer to the foetus, which may lead to foetal growth restriction, predisposing children to a…”
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FALDH Reverses the Deleterious Action of Oxidative Stress Induced by Lipid Peroxidation Product 4-Hydroxynonenal on Insulin Signaling in 3T3-L1 Adipocytes by DEMOZAY, Damien, MAS, Jean-Christophe, ROCCHI, Stephane, VAN OBBERGHEN, Emmanuel

“…FALDH Reverses the Deleterious Action of Oxidative Stress Induced by Lipid Peroxidation Product 4-Hydroxynonenal on Insulin Signaling in 3T3-L1 Adipocytes…”
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Formation of a Human β-Cell Population within Pancreatic Islets Is Set Early in Life by Gregg, Brigid E, Moore, Patrick C, Demozay, Damien, Hall, Ben A, Li, Mei, Husain, Aliya, Wright, Amy J, Atkinson, Mark A, Rhodes, Christopher J

“…Context: Insulin resistance can be compensated by increased functional pancreatic β-cell mass; otherwise, diabetes ensues. Such compensation depends not only…”
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Fatty Aldehyde Dehydrogenase by Demozay, Damien, Rocchi, Stéphane, Mas, Jean-Christophe, Grillo, Sophie, Pirola, Luciano, Chavey, Carine, Van Obberghen, Emmanuel

“…Phosphatidylinositol 3-kinase signaling regulates the expression of several genes involved in lipid and glucose homeostasis; deregulation of these genes may…”
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802-P: Beneficial Effects of a Functionally Selective Insulin on Vascular Function and Liver Triglycerides by OLSEN, GRITH S., PEDERSEN, THOMAS A., SLAABY, RITA, HANSEN, BO F., GLENDORF, TINE, DEMOZAY, DAMIEN, HVID, HENNING, NISHIMURA, ERICA, BRANDT, JAKOB, POVLEN, GRO

“…Selective insulin resistance, where insulin's ability to lower blood glucose via the Akt signaling pathway gradually decreases while retaining its…”
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β-Cell Control of Insulin Production During Starvation-Refeeding in Male Rats by Boland, Brandon B, Brown, Charles, Alarcon, Cristina, Demozay, Damien, Grimsby, Joseph S, Rhodes, Christopher J

“…Abstract Mammalian metabolism has evolved to adapt to changes in nutrient status. Insulin, the key anabolic hormone, facilitates intracellular storage of…”
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Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells by Demozay, Damien, Tsunekawa, Shin, Briaud, Isabelle, Shah, Ramila, Rhodes, Christopher J

“…Insulin receptor substrate-2 (IRS-2) plays an essential role in pancreatic islet β-cells by promoting growth and survival. IRS-2 turnover is rapid in primary…”
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215-LB: Silencing of Fructose 1,6-Bisphosphatase (FBP1) in Liver Improves Glucose Homeostasis in Insulin-Resistant Rodent and Human Models by FLEDELIUS, CHRISTIAN, IVERSEN, HELLE, INGVORSEN, RIKKE S., ERIKSEN, LISBETH B., BLOIS, ANNA, MONTAUBAN, YVENET, RIJNBRAND, RENE, HAN, WEN, JEPPESEN, JACOB F., DEMOZAY, DAMIEN

“…Insulin resistant individuals display elevated fasting and post-prandial glucose levels which are mainly driven by inadequate inhibition of gluconeogenesis…”
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FoxO feedback control of basal IRS-2 expression in pancreatic β-cells is distinct from that in hepatocytes by Tsunekawa, Shin, Demozay, Damien, Briaud, Isabelle, McCuaig, Jill, Accili, Domenico, Stein, Roland, Rhodes, Christopher J

“…Appropriate regulation of insulin receptor substrate 2 (IRS-2) expression in pancreatic β-cells is essential to adequately compensate for insulin resistance…”
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Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models by Hvid, Henning, Brand, Christian L., Hummelshøj, Tina, Jensen, Sanne, Bouman, Stephan D., Bowler, Andrew, Poulsen, Bjarne R., Tiainen, Peter, Åkertröm, Thorbjörn, Demozay, Damien, Hoeg-Jensen, Thomas, Ingvorsen, Camilla, Pedersen, Thomas Å., McGuire, Jim, Egebjerg, Thomas, Cappelen, Karen A., Eliasen, Ina P., Hansen, Bo F., Hennen, Stephanie, Stidsen, Carsten E., Olsen, Grith S., Roed, Nikolaj K.

“…Aims/hypothesis Normalisation of blood glucose in individuals with diabetes is recommended to reduce development of diabetic complications. However, risk of…”
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Toward once-monthly insulin therapy via synergy in two pharmacokinetic protractors: Fc-conjugation and fatty acid acylation by Zaykov, Alexander N, Gelfanov, Vasily M, Tagmose, Tina M, Demozay, Damien, Manfè, Valentina, Rohlfs, Rebecca, Rivir, Marita, Perez-Tilve, Diego, Finan, Brian, DiMarchi, Richard D

“…Pharmacokinetic properties and duration of therapeutic action of a pharmaceutical agent can be significantly extended through the combination of two distinct…”
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Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via [Ca.sup.2+]-dependent calcineurin/NFAT signaling in primary pancreatic islet [beta]-cells.(ORIGINAL ARTICLE) by Demozay, Damien, Tsunekawa, Shin, Briaud, Isabelle, Shah, Ramila, Rhodes, Christopher J

“…OBJECTIVE--Insulin receptor substrate-2 (IRS-2) plays an essential role in pancreatic islet [beta]-cells by promoting growth and survival. IRS-2 turnover is…”
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Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via [Ca.sup.2+]-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells by Demozay, Damien, Tsunekawa, Shin, Briaud, Isabelle, Shah, Ramila, Rhodes, Christopher J

“…OBJECTIVE--Insulin receptor substrate-2 (IRS-2) plays an essential role in pancreatic islet β-cells by promoting growth and survival. IRS-2 turnover is rapid…”
Get full text

FoxO feedback control of basal IRS-2 expression in pancreatic [beta]-cells is distinct from that in hepatocytes.(ORIGINAL ARTICLE) by Tsunekawa, Shin, Demozay, Damien, Briaud, Isabelle, McCuaig, Jill, Accili, Domenico, Stein, Roland, Rhodes, Christopher J

“…OBJECTIVE--Appropriate regulation of insulin receptor substrate 2 (IRS-2) expression in pancreatic [beta]-cells is essential to adequately compensate for…”
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Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca2+-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet β-cells by DEMOZAY, Damien, TSUNEKAWA, Shin, BRIAUD, Isabelle, SHAH, Ramila, RHODES, Christopher J

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FoxO Feedback Control of Basal IRS-2 Expression in Pancreatic β-Cells Is Distinct From That in Hepatocytes by TSUNEKAWA, Shin, DEMOZAY, Damien, BRIAUD, Isabelle, MCCUAIG, Jill, ACCILI, Domenico, STEIN, Roland, RHODES, Christopher J

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Fatty aldehyde dehydrogenase: potential role in oxidative stress protection and regulation of its gene expression by insulin by Demozay, Damien, Rocchi, Stéphane, Mas, Jean-Christophe, Grillo, Sophie, Pirola, Luciano, Chavey, Carine, Van Obberghen, Emmanuel

“…Phosphatidylinositol 3-kinase signaling regulates the expression of several genes involved in lipid and glucose homeostasis; deregulation of these genes may…”
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Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca^sup 2+^-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet [Beta]-Cells by Demozay, Damíen, Tsunekawa, Shin, Briaud, Isabelle, Shah, Ramila, Rhodes, Christopher J

“…Insulin receptor substrate-2 (IRS-2) plays an essential role in pancreatic islet [beta]-cells by promoting growth and survival. IRS-2 turnover is rapid in…”
Get full text